Science

TGA dismisses bid to make contraceptive pill available over the counter in Australia

Two applications were made to amend poisons legislation so that the pill would not need ongoing prescriptions from doctor Download the free Guardian app; get our morning email briefing A push to make the contraceptive pill available over the counter has been dismissed by Australia’s drugs regulator. In an interim decision, now open for further …

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Doctor who advocated Covid-19 therapy including ivermectin applied for patent on same unproven treatment

Exclusive: Australian professor Thomas Borody’s failure to widely declare that he could potentially profit from treatment he is promoting raises ethical concerns Get our free news app; get our morning email briefing A Sydney gastroenterologist who has been enthusiastically promoting an unapproved Covid-19 treatment, including to Australian politicians and general practitioners, has filed a patent …

Doctor who advocated Covid-19 therapy including ivermectin applied for patent on same unproven treatment Read More »

Local Covid vaccines fill gap as UN Covax scheme misses target

India, Egypt and Cuba among first states to develop and make their own vaccines as Covax falls behind Developing countries are increasingly turning to homegrown Covid vaccinations as the UN-backed Covax programme falls behind. While western countries roll out booster jabs to their own populations, Covax, which was set up by UN agencies, governments and …

Local Covid vaccines fill gap as UN Covax scheme misses target Read More »

Pfizer asks US to allow Covid vaccines for children ages five to 11

Jabs could begin within weeks if US government approves request, with children getting a third of dose given to adults Pfizer asked the US government Thursday to allow use of its Covid-19 vaccine in children ages five to 11 – and if regulators agree, shots could begin within a matter of weeks. Many parents and …

Pfizer asks US to allow Covid vaccines for children ages five to 11 Read More »

Covid-19: will there soon be a pill that stops us getting sick? – podcast

Last week the pharmaceutical company Merck released promising early data on a pill for Covid-19, which trials suggest halves hospitalisations and deaths. So what do we know about this experimental treatment? Madeleine Finlay talks to the Guardian’s science correspondent Hannah Devlin about whether this antiviral could be a gamechanger. And as some UK experts warn …

Covid-19: will there soon be a pill that stops us getting sick? – podcast Read More »

WHO endorses use of world’s first malaria vaccine in Africa

World Health Organization’s director general hails ‘historic day’ in fight against parasitic disease The World Health Organization has recommended the widespread rollout of the first malaria vaccine, in a move experts hope could save tens of thousands of children’s lives each year across Africa. Hailing “an historic day”, the WHO’s director general, Dr Tedros Adhanom …

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Coronavirus treatments: the potential ‘game-changers’ in development

After positive clinical trials for antiviral drug Molnupiravir, it joins other medicines that have shown promise Coronavirus – latest updates See all our coronavirus coverage The first clinical trial results showing a positive effect for a pill that can be taken at home has been hailed as a potential gamechanger that could provide a new …

Coronavirus treatments: the potential ‘game-changers’ in development Read More »

Covid antiviral pill halves hospitalisations and deaths, maker says

If approved, Merck’s drug would be first simple oral medication shown to be effective against coronavirus Coronavirus – latest updates See all our coronavirus coverage The first pill to treat coronavirus could be available within months after it was found to cut hospitalisations and deaths by half. If approved, the antiviral drug would be the …

Covid antiviral pill halves hospitalisations and deaths, maker says Read More »

Ministers told to bar EU from UK trial data in vaccines row

England’s deputy medical chief asked for data to be withheld unless British vaccine guinea pigs allowed to travel abroad • Coronavirus – latest updates• See all our coronavirus coverage England’s deputy chief medical officer asked ministers to withhold all UK clinical trial data from the EU if European countries continued to deny entry to British …

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GSK teams with King’s College to use AI to fight cancer

Artificial intelligence will be used to develop personalised treatments while investigating role of genetics The pharmaceuticals firm GSK has struck a five-year partnership with King’s College London to use artificial intelligence to develop personalised treatments for cancer by investigating the role played by genetics in the disease. The tie-up, which involves 10 of the drug …

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A year that changed the world – and medical companies’ fortunes

While Covid sent many firms to the wall, others prospered by spotting opportunities, from test kits to mask coatings The pandemic has taken a heavy toll on business, gutting high streets as familiar names fell into receivership. But for some less well-known firms, the past 18 months have been transformational. Those that have thrived did …

A year that changed the world – and medical companies’ fortunes Read More »

UK approves rollout of ‘first of its kind’ Covid antibody treatment

Ronapreve can be used to treat symptoms of acute infection after successful clinical trials Coronavirus – latest updates See all our coronavirus coverage The medicines regulator has approved use of the first treatment in the UK using artificial antibodies to prevent and fight Covid-19. The health secretary, Sajid Javid, said approval of the first drug …

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Hundreds of UK and EU cosmetics products contain ingredients tested on animals

New analysis finds chemicals tested on animals in moisturisers, lipsticks, hair conditioner and sunscreen, despite ban Hundreds of cosmetic products sold in the UK and Europe contain ingredients that have been tested on animals, despite bans that outlawed such testing years ago, a new analysis has shown. Banned tests were performed on ingredients used in …

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Covid drug could help reduce heavy menstrual bleeding

Trial suggests anti-inflammatory dexamethasone may offer welcome alternative to intra-uterine system Researchers hope a steroid that shot to prominence during the Covid pandemic may help reduce blood loss in those who experience heavy periods. The cheap anti-inflammatory dexamethasone was discovered to improve survival rates among patients critically ill with Covid. It is also used for …

Covid drug could help reduce heavy menstrual bleeding Read More »

As Delta spreads, Pfizer and Moderna get set for a booster shot to profits

The firms are already taking the lion’s share of earnings from the market, as this week’s results will show Praised for preventing hundreds of thousands of deaths and allowing a return to more normal life, Covid vaccines will also substantially benefit some pharmaceutical companies. In June, analysts estimated the global market for the vaccines could …

As Delta spreads, Pfizer and Moderna get set for a booster shot to profits Read More »

AstraZeneca sales of Covid vaccine triple to $1.2bn in first half of 2021

Not-for-profit pledge sees British firm’s sales revenue fall significantly short of US rival Pfizer Coronavirus – latest updates See all our coronavirus coverage AstraZeneca’s Covid-19 vaccine has brought in $1.2bn (£900m) in the first half of this year, with sales tripling in the second quarter from the first – but its earnings remained significantly below …

AstraZeneca sales of Covid vaccine triple to $1.2bn in first half of 2021 Read More »

Is medical cannabis really a magic bullet?

Research increasingly suggests that extracts from the plant are effective in treating pain, anxiety, epilepsy and more, but experts still preach caution around recreational use In 2017, Mikael Sodergren, a liver and pancreatic cancer surgeon at Imperial College healthcare NHS trust, was finding himself becoming increasingly interested in the potential role of medical cannabis in …

Is medical cannabis really a magic bullet? Read More »

GSK plans £400m life sciences campus in Stevenage

Pharmaceuticals firm thinks creating cluster of companies at its site could result in up to 5,000 jobs GlaxoSmithKline is seeking to create a £400m campus in Stevenage for new life sciences companies that it believes could result in up to 5,000 jobs over the next decade. The pharmaceuticals company has kicked off a process to …

GSK plans £400m life sciences campus in Stevenage Read More »

Oxford drugs firm gains $1.5m Gates grant for Covid-19 therapy

Exclusive: Exscientia to use AI in proposed fast-track development of ‘low-cost’ pill for Sars viruses Coronavirus – latest updates See all our coronavirus coverage Exscientia, an Oxford-based firm that uses artificial intelligence to develop medicines, has won a $1.5m grant from the Bill & Melinda Gates Foundation to create a Covid-19 treatment that also works …

Oxford drugs firm gains $1.5m Gates grant for Covid-19 therapy Read More »

UK supercomputer Cambridge-1 to hunt for medical breakthroughs

Computer – the most powerful in Britain – will use AI to find new cures and deepen understanding of diseases The UK’s most powerful supercomputer, which its creators hope will make the process of preventing, diagnosing and treating disease better, faster and cheaper, is operational. Christened Cambridge-1, the supercomputer represents a $100m investment by US-based …

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Centre Court ovations, limbo-dancing grans – it’s all been humbling, say Oxford vaccine creators

Sarah Gilbert and Catherine Green tell of their pioneering vaccine work but warn the battle is far from over Coronavirus – latest updates See all our coronavirus coverage Sarah Gilbert’s experiences at Wimbledon last week clearly had a profound impact on the medical researcher – though it was not the standing ovation that the vaccine …

Centre Court ovations, limbo-dancing grans – it’s all been humbling, say Oxford vaccine creators Read More »

The Oxford vaccine: the trials and tribulations of a world-saving jab

Amid bemusement from scientists at the deluge of often undeserved criticism, the Guardian pieces together the story behind the vaccine’s successes and failures Coronavirus – latest updates See all our coronavirus coverage In January 2020, when most of the world slept soundly in ignorance of the pandemic coming its way, a group of scientists at …

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Moderna, Pfizer or AstraZeneca? The ridiculous, diverting rise of vaccine envy

Casual vaccine chat is today’s only form of small talk, so it’s not surprising it would take a lightheartedly tribal turn. Ultimately, of course, gratitude is at the heart of the conversation Last week, I had cause to go searching for images of men getting vaccinated (it’s not a fetish – it was for work) …

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Covid jabs for billions of humans will earn their makers billions of dollars

We look at the drug firms – led by Pfizer and Moderna – that are set to profit most in an unprecedented global vaccination drive Coronavirus – latest updates See all our coronavirus coverage Drugmakers led by US firms Pfizer and Moderna stand to make tens of billions of dollars from their Covid-19 vaccines this …

Covid jabs for billions of humans will earn their makers billions of dollars Read More »

Ronald Cresswell obituary

Pharmaceutical researcher with a flair for business who brought a string of vital drugs to market In 1960 the chemist Ronald Cresswell, who has died aged 86, had a lucky break. As a result of travelling from Glasgow to take up a post in New York he attended a conference of the American Chemical Society, …

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More research funding needed to avoid drug-resistant pandemic, warns report

Smaller firms are developing most antibiotics targeting superbugs but often at risk of bankruptcy Small drugmakers and biotech firms that are developing the bulk of new antibiotics need far more financial support, according to a new report, which warned that without these life-saving medicines there could be a pandemic of drug-resistant infections, worse than Covid-19. …

More research funding needed to avoid drug-resistant pandemic, warns report Read More »

Helen Murray Free obituary

Chemist who transformed medical screening by developing glucose dipsticks In the 1950s the US chemist Helen Murray Free, who has died aged 98, was responsible for developing glucose dipsticks. Their use led to much simpler medical screening methods that are still widely used today for pregnancy tests, the diagnosis and monitoring of diabetes, and to …

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German scientists say they can help improve Covid vaccines to prevent blood clots

AstraZeneca and Johnson & Johnson jabs have caused rare blood clots but scientists say they can be redesigned to avoid problem Coronavirus – latest updates See all our coronavirus coverage A team of German scientists believe that they have worked out why some people given the AstraZeneca and Johnson & Johnson vaccines against Covid-19 develop …

German scientists say they can help improve Covid vaccines to prevent blood clots Read More »

Investors flock to life sciences as UK sector breaks funding record

Covid crisis spurs growing interest in drugmakers, diagnostics and medical equipment firms UK drugmakers, diagnostics, medical equipment and other life sciences companies have raised £10.6bn from private funding rounds and stock market flotations in the first three months of the year, more than half of last year’s record total, according to a report. Last year, …

Investors flock to life sciences as UK sector breaks funding record Read More »

What Covid vaccines does the UK have and which are in the works?

As Valneva recruits volunteers for final stage trials of its vaccine, here is the current state of play in Britain Coronavirus – latest updates See all our coronavirus coverage Vaccines to protect against the coronavirus were designed, tested and manufactured in record time, and several have been approved for use in the UK vaccination programme, …

What Covid vaccines does the UK have and which are in the works? Read More »

Oxford/AstraZeneca Covid vaccine research ‘was 97% publicly funded’

Analysis rebuts claim by Boris Johnson that jab was developed ‘because of greed’ Coronavirus – latest updates See all our coronavirus coverage At least 97% of the funding for the development of the Oxford/AstraZeneca Covid-19 vaccine has been identified as coming from taxpayers or charitable trusts, according to the first attempt to reconstruct who paid …

Oxford/AstraZeneca Covid vaccine research ‘was 97% publicly funded’ Read More »

Will Covid vaccines protect us against new variants? | Julian Tang

New strains such as the South African variant that’s emerged in south London will require constant vigilance as lockdown eases All viruses mutate. They do this to adapt and survive better in their specific host. The virus that causes Covid-19 is no different: it has moved from the animal realm, where it most likely originated …

Will Covid vaccines protect us against new variants? | Julian Tang Read More »

UK strategy of backing several Covid vaccines seems to be paying off

Analysis: buying new and existing technologies ensured alternatives if a vaccine failed or had supply issues Coronavirus – latest updates See all our coronavirus coverage The government has said the decision by Johnson & Johnson to delay the supply of its Covid vaccine to Europe, while the US investigates reports of six cases of unusual …

UK strategy of backing several Covid vaccines seems to be paying off Read More »

Global Covid vaccine rollout threatened by shortage of vital components

Pharmaceutical firms warn of delays to items such as the large bags in which vaccine cells are grown Coronavirus – latest updates See all our coronavirus coverage Vaccine-makers around the world face shortages of vital components including large plastic growbags, according to the head of the firm that is manufacturing a quarter of the UK’s …

Global Covid vaccine rollout threatened by shortage of vital components Read More »

Clarity and openness are key to vaccine confidence | Letters

Readers respond to the latest recommendations about the AstraZeneca Covid vaccine Your editorial calling for clarity on the AstraZeneca vaccine’s side-effects risks both being unclear and undermining confidence (The Guardian view on the AstraZeneca vaccine: confidence from clarity, 7 April). You imply that the rate of potentially serious cerebral venous sinus thrombosis is 0.0001%. The …

Clarity and openness are key to vaccine confidence | Letters Read More »

Medicines watchdog says no decision made AstraZeneca jab for under-30s

Medicines Healthcare products Regulatory Authority was considering restricting vaccine amid concerns over rare blood clots Coronavirus – latest updates See all our coronavirus coverage The UK’s medicines regulatory body has said that no decision has been made on any regulatory action relating to the Oxford/AstraZeneca vaccine following reports it is considering restricting use of the …

Medicines watchdog says no decision made AstraZeneca jab for under-30s Read More »

Two new vaccines on the way – with more to follow this year

Half of UK adults have had a first jab, and future supplies of millions of doses look assured Coronavirus – latest updates See all our coronavirus coverage Two very different jabs have been responsible for inoculating Britain’s strikingly high number of vaccine recipients – with more than half of the country’s adult population having now …

Two new vaccines on the way – with more to follow this year Read More »

Pfizer vaccine has 91% efficacy for up to six months, trial shows

Findings based on two doses three weeks apart are first to show shot remains effective for many months Coronavirus – latest updates See all our coronavirus coverage The coronavirus vaccine developed by Pfizer and its German partner BioNTech protects against symptomatic Covid for up to six months, an updated analysis of clinical trial data has …

Pfizer vaccine has 91% efficacy for up to six months, trial shows Read More »

Canada suspends use of AstraZeneca Covid vaccine for those under 55

Immunisation panel says there is ‘substantial uncertainty about the benefit’ of the vaccine given risk of rare type of blood clot See all our coronavirus coverage Canada on Monday suspended the use of the Oxford/AstraZeneca coronavirus vaccine for people under 55 following concerns it might be linked to rare blood clots. The pause was recommended …

Canada suspends use of AstraZeneca Covid vaccine for those under 55 Read More »

Safe, stable, sold at cost: AstraZeneca’s vaccine deserves celebration, not scorn

The company has struggled, like its rivals, to keep up with demand. But it has achieved great things at low prices AstraZeneca is one of the shining stars of the pandemic. Not only did it produce a vaccine where other big players failed, the UK-Swedish company has pledged to sell it at cost until it …

Safe, stable, sold at cost: AstraZeneca’s vaccine deserves celebration, not scorn Read More »

US agency questions AstraZeneca’s Covid vaccine trial data

Drug firm may have provided incomplete view of efficacy data from US trial, says safety monitor Coronavirus – latest updates See all our coronavirus coverage The Oxford/AstraZeneca vaccine against Covid has been dealt another blow within hours of AstraZeneca posting excellent results from its long-awaited big trial in the US. Questions have been raised in …

US agency questions AstraZeneca’s Covid vaccine trial data Read More »

Patrick Vallance: the adviser who spoke scientific truth to power

The UK’s chief scientific adviser loves good food, enjoys a Scandi drama – and has been called ‘the richest civil servant in history’ Sir Patrick Vallance spent his 60th birthday at a podium in Downing Street, flanking Boris Johnson. Whatever plans he had were scrapped. Continue reading…

Patrick Vallance: the adviser who spoke scientific truth to power

The UK’s chief scientific adviser loves good food, enjoys a Scandi drama – and has been called ‘the richest civil servant in history’ Sir Patrick Vallance spent his 60th birthday at a podium in Downing Street, flanking Boris Johnson. Whatever plans he had were scrapped. Continue reading…

Benefits of Oxford/AstraZeneca vaccine outweigh any risk, says EMA

European agency seeks to allay blood clot fears as Germany, France and Italy temporarily suspend use Coronavirus – latest updates See all our coronavirus coverage Europe’s medicines regulator has moved to stifle spiralling concern about the Oxford/AstraZeneca vaccine, saying the shot’s benefits outweigh the risks after four major EU countries announced they were suspending its …

Benefits of Oxford/AstraZeneca vaccine outweigh any risk, says EMA Read More »

Harris Poll Finds Large Boost in Pharma Industry Reputation

As the COVID-19 vaccine roll-out gains in intensity, it has become common to hear people toss out the names of pharmaceutical companies like Pfizer, Moderna and AstraZeneca with the same ease that they refer to their favorite brands of ketchup or peanut butter. This isn’t typical. While direct-to-consumer advertising has perhaps increased some awareness of …

Harris Poll Finds Large Boost in Pharma Industry Reputation Read More »

What price a child’s life? India’s quest to make rare disease drugs affordable

Parents whose only hope was finding foreign sponsorship or a clinical trial are now looking for homegrown breakthroughs For three years, Vidya tried to find the cause of her son’s recurrent fevers and low cognitive development. When she found out, she was devastated. Vineeth, 10, has an incurable illness – mucopolysaccharidosis type 2 – that …

What price a child’s life? India’s quest to make rare disease drugs affordable Read More »

Ireland suspends AstraZeneca Covid vaccine over blood clot concerns

Deployment of Oxford vaccine temporarily deferred after latest reports from Norway Coronavirus – latest updates See all our coronavirus coverage Ireland is suspending use of the Oxford/AstraZeneca vaccine against Covid as a precautionary measure following further reports of blood clots in people who have received it, this time from Norway. The deputy chief medical officer, …

Ireland suspends AstraZeneca Covid vaccine over blood clot concerns Read More »

At AstraZeneca, we know that until everyone is safe from Covid, no one is safe | Pascal Soriot

The scientific community are rising to the challenge, undertaking an unprecedented global health programme Pascal Soriot is the chief executive officer of AstraZeneca Coronavirus – latest updates See all our coronavirus coverage Covid-19 is a virus that knows no boundaries and has inflicted terrible suffering across the world. Now more than ever, we must remember …

At AstraZeneca, we know that until everyone is safe from Covid, no one is safe | Pascal Soriot Read More »

From Pfizer to Moderna: who’s making billions from Covid vaccines?

The companies in line for the biggest gains – and the shareholders who have already made fortunes Coronavirus – latest updates See all our coronavirus coverage The arrival of Covid-19 vaccines promises a return to more normal life – and has created a global market worth tens of billions of dollars in annual sales for …

From Pfizer to Moderna: who’s making billions from Covid vaccines? Read More »

Covid: Germany and France under pressure to shift Oxford vaccine

Both countries urged to take action to avoid pile-up of unused AstraZeneca vaccine doses Coronavirus – latest updates See all our coronavirus coverage Authorities in Germany and France are under pressure to come up with creative solutions to shift the AstraZeneca vaccine at higher speed in order to avoid a pile-up of unused doses over …

Covid: Germany and France under pressure to shift Oxford vaccine Read More »

Drug companies look to AI to end ‘hit and miss’ research

Technology that speeded the development of Covid vaccines has potential to transform the pharmaceutical industry The hunt for new medicines has often been more like a game of roulette than high-end science. But now the pharmaceutical sector is on the cusp of a transformation, as it delves into cutting-edge technology to come up with new …

Drug companies look to AI to end ‘hit and miss’ research Read More »

German politicians counter AstraZeneca vaccine scepticism with show of support

Oxford Covid vaccine described in German media as ‘shelf warmer’ with only 17% of doses administered so far Coronavirus – latest updates See all our coronavirus coverage Politicians in Germany are stepping out in support of the AstraZeneca vaccine as public scepticism around the Oxford-developed product is threatening to hamper Europe’s Covid-19 immunisation programme. The …

German politicians counter AstraZeneca vaccine scepticism with show of support Read More »

Life savers: the amazing story of the Oxford/AstraZeneca Covid vaccine

A year ago, two scientists began work on the response to a new virus. Now, as their vaccine is being given to millions, they tell of their incredible 12 months Exactly a year ago, Oxford University scientists launched a joint enterprise that is set to have a profound impact on the health of our planet. …

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AstraZeneca says vaccine against new Covid variants may take six months

Anglo-Swedish pharmaceutical firm’s profits rise to $7.4bn as main business ‘remains strong’ Coronavirus – latest updates See all our coronavirus coverage AstraZeneca has said it could take between six and nine months to produce Covid-19 vaccines that are effective against new variants of the coronavirus. The company’s vaccine, developed jointly with scientists at the University …

AstraZeneca says vaccine against new Covid variants may take six months Read More »

A series of knocks: Oxford/AstraZeneca’s bumpy road to Covid vaccine confidence

From doubts about safety in older people to questions about variants, scientists have faced a battle to convince the public and regulators Coronavirus – latest updates See all our coronavirus coverage The Oxford University/AstraZeneca vaccine against Covid has barely been out of the news from the moment the race to protect the world’s population from …

A series of knocks: Oxford/AstraZeneca’s bumpy road to Covid vaccine confidence Read More »

AstraZeneca set to weather Covid in better health than rivals

The Anglo-Swedish firm already had a strong lineup of cancer drugs when vaccine success gave it a further boost Before the pandemic, AstraZeneca was highly regarded in the business and pharmaceutical world – seen as one of the UK’s best companies. Now, thanks to Britain’s successful vaccine programme, it is a household name. The Anglo-Swedish …

AstraZeneca set to weather Covid in better health than rivals Read More »

Oxford Covid vaccine just as effective against Kent variant, trials suggest

Scientists behind AstraZeneca vaccine say it has similar efficacy against variant as against original Covid Coronavirus – latest updates See all our coronavirus coverage The Oxford/AstraZeneca coronavirus vaccine is just as effective at fighting the UK variant as it is the original virus, new research suggests. Oxford University researchers who developed the vaccine say it …

Oxford Covid vaccine just as effective against Kent variant, trials suggest Read More »

GSK and CureVac sign £132m deal to develop multi-variant Covid vaccine

Companies hope to have next generation of vaccines against emerging variants by next year GlaxoSmithKline and Germany’s CureVac have reached a €150m (£132m) agreement to develop a next generation of Covid-19 vaccines targeting new emerging variants in the pandemic. The two companies said they they plan to work jointly to develop a vaccine that can …

GSK and CureVac sign £132m deal to develop multi-variant Covid vaccine Read More »

Even with vaccines, we still need treatments for Covid. So what works?

Analysis: death rates in intensive care are falling as doctors identify more ways to help those with the disease Coronavirus – latest updates See all our coronavirus coverage Vaccines may have been described as the great escape route from the Covid pandemic – but treatments, which are bringing down death rates, will be needed as …

Even with vaccines, we still need treatments for Covid. So what works? Read More »

UK vaccine strategy ‘paying off’ as latest trials boost stockpiles

Pre-ordering of Janssen and Novavax means Britain has procured 247m successfully trialled jabs Coronavirus – latest updates See all our coronavirus coverage Britain has cemented its status as one of the world’s leading buyers of effective Covid vaccines after two more pharmaceutical companies reported positive trial results – potentially growing the UK stockpile by 90m …

UK vaccine strategy ‘paying off’ as latest trials boost stockpiles Read More »

How effective is the Novavax Covid vaccine and will it work against variants?

Everything you need to know about the trial results for a new coronavirus vaccine Coronavirus – latest updates See all our coronavirus coverage In an interim analysis of a phase 3 clinical trial conducted in the UK, the vaccine has been shown to be nearly 89% effective, with 27% of participants in the trial – …

How effective is the Novavax Covid vaccine and will it work against variants? Read More »

How effective is the Novavax Covid vaccine and will it work against variants?

Everything you need to know about the trial results for a new coronavirus vaccine Coronavirus – latest updates See all our coronavirus coverage In an interim analysis of a phase 3 clinical trial conducted in the UK, the vaccine has been shown to be nearly 89% effective, with 27% of participants in the trial – …

How effective is the Novavax Covid vaccine and will it work against variants? Read More »

AstraZeneca denies pulling out of talks as EU Covid vaccine row deepens

Latest round of crunch talks to discuss breakdown in supplies still happening, says spokesman Coronavirus – latest updates See all our coronavirus coverage A row over coronavirus vaccine shortages in the EU has descended into farce as AstraZeneca denied claims by the European commission that it had pulled out of a crunch meeting over a …

AstraZeneca denies pulling out of talks as EU Covid vaccine row deepens Read More »

EU means business over Covid vaccine exports, says Von der Leyen

Commission president says firms must deliver on orders after AstraZeneca warns of shortfall Coronavirus – latest updates See all our coronavirus coverage The EU “means business”, Ursula von der Leyen has said, as the bloc doubled down on plans for tighter monitoring of vaccine exports to countries outside of the union, such as the UK. …

EU means business over Covid vaccine exports, says Von der Leyen Read More »

German government challenges AstraZeneca Covid vaccine efficacy reports

Newspaper had reported that government was expecting European regulator’s assessment to show that vaccine was only 8% effective among over-65 The German government has challenged reports of a lower-than-expected efficacy rate of the AstraZeneca vaccine for older people, while reiterating concerns about the British-Swedish pharmaceutical giant’s data reporting. An article in German business daily Handelsblatt …

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Germany to administer Covid drugs used to treat Donald Trump

Country will be first in EU to use antibody cocktails after government buys 200,000 doses Specialist clinics in Germany will this week become the first hospitals in the EU to treat Covid-19 patients with expensive and experimental antibody cocktails used to treat the former US president Donald Trump after he caught the virus last October. …

Germany to administer Covid drugs used to treat Donald Trump Read More »

Vaccine experts call for clarity on UK’s 12-week Covid jab interval

British Society for Immunology calls for a robust programme monitoring the body’s immune response Experts have called for greater clarity on the monitoring in place to assess the 12-week dosing interval for Covid-19 vaccines, as the row over delayed second doses continues. The UK’s coronavirus vaccination programme was shifted late last year to prioritise administering …

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Vaccine experts call for clarity on UK’s 12-week Covid jab interval

British Society for Immunology calls for a robust programme monitoring the body’s immune response Experts have called for greater clarity on the monitoring in place to assess the 12-week dosing interval for Covid-19 vaccines, as the row over delayed second doses continues. The UK’s coronavirus vaccination programme was shifted late last year to prioritise administering …

Vaccine experts call for clarity on UK’s 12-week Covid jab interval Read More »

I’ve had my first vaccine jab. It gives me hope of liberation… but not yet

Exactly a year after his first story about coronavirus, our science editor received the Pfizer injection last week. Here he reflects on a remarkable scientific achievement Coronavirus – latest updates See all our coronavirus coverage I marked a grim anniversary in an unexpected manner last week. On 18 January last year, I wrote my first …

I’ve had my first vaccine jab. It gives me hope of liberation… but not yet Read More »

WHO platform for pharmaceutical firms unused since pandemic began

Exclusive: ‘pool’ to share Covid-19 information has received no contributions since May 2020 Coronavirus – latest updates See all our coronavirus coverage A World Health Organization program for pharmaceutical companies to voluntarily share Covid-19 related knowledge, treatments and technology so they can be more widely distributed has attracted zero contributions in the eight months since …

WHO platform for pharmaceutical firms unused since pandemic began Read More »

UK to face short term delay in delivery of Pfizer vaccine

Overall number of doses delivered between January and March will remain the same, the firm says Coronavirus – latest updates See all our coronavirus coverage The UK is set to face short-term delays in delivery of the Pfizer/BioNTech coronavirus vaccine as the pharmaceutical company upgrades its production capacity. Pfizer is upscaling production at its plant …

UK to face short term delay in delivery of Pfizer vaccine Read More »

Second shots of Covid vaccine could be delayed further in England

Evidence growing that spacing doses of Pfizer vaccine improves effectiveness Coronavirus – latest updates See all our coronavirus coverage Second shots of coronavirus vaccine could be delayed even further amid growing evidence that spacing out the doses improves their effectiveness. The NHS vaccination programme aims to immunise about 14 million people at greatest risk of …

Second shots of Covid vaccine could be delayed further in England Read More »

Britain could be mass-producing its Covid shot. Shame we junked our industrial base | Aditya Chakrabortty

The dire state of UK manufacturing has left us dependent on other nations. We may soon find out why some call this a ‘national security risk’ Everything now hinges on a vaccine: how many more Britons die, whether the NHS finally breaks, how long the UK stays locked down. All depends on how fast the …

Britain could be mass-producing its Covid shot. Shame we junked our industrial base | Aditya Chakrabortty Read More »

UK vaccine minister vows ‘massive uplift’ in number of jabs this week

Nadhim Zahawi says ‘absolute focus’ is to get 13.9 million people inoculated by mid-February Coronavirus – latest updates See all our coronavirus coverage The UK vaccine minister, Nadhim Zahawi, has pledged a “massive uplift” in the number of coronavirus vaccinations carried out this week as he said reaching the government’s target of 13.9m jabs offered …

UK vaccine minister vows ‘massive uplift’ in number of jabs this week Read More »

Medical Writing Landscape Advancement Summit | Virtual

The Lincoln Health Network is excited to announce our 2nd Medical Writing Landscape Advancement Summit, March 3-4, 2021. Join us virtually, on the LHN virtual event platform to improve your medical writing strategies by understanding evolving regulatory protocols and submission guidelines, and learn how to improve quality and content optimizations. Visit our website for our …

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Analysis: is it wise for England to mix and match Covid vaccines?

US experts warn against plan to give different second jab if supplies run low Coronavirus – latest updates See all our coronavirus coverage The UK is setting the pace around the world in the approval and use of Covid vaccines but, while other countries watch intently, not all are yet prepared to embrace what looks …

Analysis: is it wise for England to mix and match Covid vaccines? Read More »

What difference will Oxford/AstraZeneca vaccine make in UK?

We look at how the introduction of a new vaccine in the fight against Covid will work Coronavirus – latest updates See all our coronavirus coverage The Oxford/AstraZeneca vaccine is central to the government’s plans for ending social distancing in the UK and returning to some sort of normality. It has invested in seven different …

What difference will Oxford/AstraZeneca vaccine make in UK? Read More »

Change in vaccine policy is a high-stakes gamble | Letters

The effectiveness of delaying the second dose of Covid vaccines must be carefully monitored, argues Dr Grizelda George, while Jan Mortimer and Jenny van Tinteren fear the move will increase distrust and uncertainty The manufacturer of the Pfizer/BioNTech vaccine has said its efficacy has only been assessed for two doses given three weeks apart. Therefore …

Change in vaccine policy is a high-stakes gamble | Letters Read More »

Questions hang over UK’s rollout of Oxford/AstraZeneca jab

Analysis: regulator surprises by approving 12-week gap between first and second shots of vaccine as well as Pfizer/BioNTech shot Coronavirus – latest updates See all our coronavirus coverage It’s a pragmatic solution to an incredibly urgent problem – how to immunise very large numbers of people at risk from a rampaging variant of Covid-19 in …

Questions hang over UK’s rollout of Oxford/AstraZeneca jab Read More »

UK scientists trial drug to prevent coronavirus infection leading to disease

Exclusive: antibody therapy could confer instant immunity against Covid-19 to at-risk groups See all our coronavirus coverage British scientists are trialling a new drug that could prevent someone who has been exposed to coronavirus from going on to develop the disease Covid-19, which experts say could save many lives. The antibody therapy would confer instant …

UK scientists trial drug to prevent coronavirus infection leading to disease Read More »

Government ‘operated illegal buy British policy’ over Covid contracts

Other firms better placed to supply antibody tests, argues case against health secretary Matt Hancock Coronavirus – latest updates See all our coronavirus coverage The government was operating an illegal “buy British” policy when it signed contracts with a small UK firm to supply Covid antibody tests, claim lawyers who have filed a case against …

Government ‘operated illegal buy British policy’ over Covid contracts Read More »

British American Tobacco wins approval to test Covid vaccine on humans

Treatment grown on tobacco plants gets US backing for clinical study Coronavirus – latest updates See all our coronavirus coverage British American Tobacco has moved a step closer to producing a vaccine for coronavirus using tobacco plants, as it won approval in the US to begin testing on humans. The company behind cigarette brands including …

British American Tobacco wins approval to test Covid vaccine on humans Read More »

Can the UK deliver on the Covid vaccine rollout? | Stephen Buranyi

The challenge of delivering vaccines on this scale are hard, but are firmly within the world of logistics, engineering, and politics Coronavirus – latest updates See all our coronavirus coverage The UK has become the first country to approve one of the coronavirus vaccines that the entire world has been desperately waiting for. And on …

Can the UK deliver on the Covid vaccine rollout? | Stephen Buranyi Read More »

Covid vaccines: US regulator sceptical over AstraZeneca model

Vaccine developed in Oxford criticised by FDA with efficacy rates and trials delaying official take-up Coronavirus – latest updates See all our coronavirus coverage For a man presenting landmark results from trials of a vaccine that it is hoped will save the world from a devastating pandemic, Sir Menelas Pangalos did not look cheerful on …

Covid vaccines: US regulator sceptical over AstraZeneca model Read More »

NHS told not to give Pfizer vaccine to extreme allergy sufferers after two people have reaction

Anyone scheduled to receive vaccine will be asked about history of allergic reactions Coronavirus – latest updates See all our coronavirus coverage Regulators have issued a warning that people who have a history of “significant” allergic reactions should not currently receive the Pfizer/BioNTech Covid-19 vaccine after two people who had the jab on Tuesday had …

NHS told not to give Pfizer vaccine to extreme allergy sufferers after two people have reaction Read More »

Covid-19 vaccine ‘very safe and highly effective’, UK health chief says

Vaccine safety message ‘vitally important’, head of medicines regulator tells Andrew Marr Show Coronavirus – latest updates See all our coronavirus coverage Public health messaging that people can have faith in the safety of coronavirus vaccines is “vitally important”, the leader of the body that has approved the Pfizer jab has said. Dr June Raine, …

Covid-19 vaccine ‘very safe and highly effective’, UK health chief says Read More »

The vaccine miracle: how scientists waged the battle against Covid-19

We trace the extraordinary research effort, from the discovery of the virus’s structure to the start of inoculations this week Coronavirus – latest updates See all our coronavirus coverage In the early afternoon of 3 January this year, a small metal box was delivered to the Shanghai Public Health Clinical Centre addressed to virus expert …

The vaccine miracle: how scientists waged the battle against Covid-19 Read More »

Covid vaccines offer chance for big pharma to improve its image

They make life-saving medicines, but no one likes them. Could this year be a turning point? Coronavirus – latest updates See all our coronavirus coverage Never before has the world awaited a new medicine with such bated breath. A vaccine for Covid-19 has the potential to unlock society and save millions of people from death …

Covid vaccines offer chance for big pharma to improve its image Read More »

How does the Pfizer/BioNTech vaccine work and who will get it?

Covid vaccine with an efficacy of almost 95% has been authorised by the UK medicines regulator Coronavirus – latest updates See all our coronavirus coverage The Pfizer/BioNTech Covid vaccine, which has an efficacy of almost 95%, has been authorised by the UK medicines regulator, making the UK the first western country to license a vaccine …

How does the Pfizer/BioNTech vaccine work and who will get it? Read More »

Oxford controversy is the first shot in international battle over vaccine efficiency

Trials will not reveal all the facts on prevention for each new drug – that process could last for years Coronavirus – latest updates See all our coronavirus coverage In a few days, researchers plan to solve a medical mystery that threatens to erupt into a major transatlantic battle. Scientists at Oxford University say they …

Oxford controversy is the first shot in international battle over vaccine efficiency Read More »

Different age groups may get different Covid vaccines, experts say

Oxford/AstraZeneca planning new trial of lower-dose jab to see how well it works in older people Coronavirus – latest updates See all our coronavirus coverage Concerns around the efficacy of the Oxford University/AstraZeneca coronavirus jab in older people could lead to different age groups being given different vaccines, experts have said. The partners announced last …

Different age groups may get different Covid vaccines, experts say Read More »

BioNTech’s Covid vaccine is a triumph of innovation and immigration | Hans-Werner Sinn

Pioneered by a Turkish-German couple, its significance exceeds its practical value The world took note when the German startup BioNTech announced its breakthrough in the development of a new type of vaccine to combat Covid-19. After testing tens of thousands of people, BioNTech’s vaccine has been shown to be 95% effective in providing protection for …

BioNTech’s Covid vaccine is a triumph of innovation and immigration | Hans-Werner Sinn Read More »

Here’s how to tackle the Covid-19 anti-vaxxers | Will Hanmer-Lloyd

Do not demonise. To optimise the vaccine rollout, all of us must show respect to those who are unsure about inoculations Will Hanmer-Lloyd is a behavioural strategist The Covid-19 vaccines, which are up to 95% effective, have the potential to save millions of lives in the UK and many more around the world. Yet creating …

Here’s how to tackle the Covid-19 anti-vaxxers | Will Hanmer-Lloyd Read More »

A vaccine revolution | podcast

Results from clinical trials have shown that the world has three apparently highly effective vaccines for Covid-19. With the race now on for regulatory approval, production and distribution, is the end of the pandemic within reach? After a gruelling year of successive waves of Covid-19 infections and national lockdowns there has been a burst of …

A vaccine revolution | podcast Read More »

Vaccine results bring us a step closer to ending Covid, says Oxford scientist

Latest breakthrough comes as PM says he hopes most at-risk could be immunised by Easter Coronavirus – latest updates See all our coronavirus coverage The world is moving a step closer to ending the coronavirus pandemic, the scientist behind Britain’s first vaccine has declared, as Boris Johnson said he hoped the majority of those most …

Vaccine results bring us a step closer to ending Covid, says Oxford scientist Read More »

‘It’s a great day’: Oxford coronavirus vaccine volunteers on trial data

Trial participants react to news that Oxford AstraZeneca Covid vaccine has up to 90% efficacy Coronavirus – latest updates See all our coronavirus coverage Dan McAteer describes his reaction more as a sense of relief than elation when his phone pinged on Monday morning with a push alert reporting that the Oxford AstraZeneca vaccine has …

‘It’s a great day’: Oxford coronavirus vaccine volunteers on trial data Read More »

Oxford AstraZeneca results open up Covid vaccine to developing countries

Jab can be kept in fridge and is part of global initiative to distribute doses at limited cost Coronavirus – latest updates See all our coronavirus coverage The efficacy of the Oxford University/AstraZeneca vaccine opens the way for a cheap and more easily transportable vaccine to be made available to some of the world’s poorest …

Oxford AstraZeneca results open up Covid vaccine to developing countries Read More »

The Guardian view on coronavirus and vaccine scepticism: time to act | Editorial

Plans for mass immunisation against Covid-19 are developing fast, but concerns must be addressed In the 1960s, academics studying rumours drew inspiration from epidemiology. They noted how such stories spread through communities, “infecting” some individuals while others seemed immune, and how more resistant populations could stop their spread. Their insights have in turn been taken …

The Guardian view on coronavirus and vaccine scepticism: time to act | Editorial Read More »

Do mRNA vaccines for Covid signal a new era in disease prevention? | Adam Finn

No one knew whether mRNA technology would work against this virus – but it does. It’s an extraordinary moment for science Coronavirus – latest updates See all our coronavirus coverage The past few months have brought a number of scientific terms to public attention. We’ve had to digest R (a virus’s reproduction number) and PCR …

Do mRNA vaccines for Covid signal a new era in disease prevention? | Adam Finn Read More »

UK faces calls to drop opposition to patent-free Covid vaccines

Request will be made at WTO meeting in order to allow mass production of treatments Coronavirus – latest updates See all our coronavirus coverage The UK will be asked to reconsider its opposition to waiving intellectual property rights for Covid-19 vaccines and treatments at a World Trade Organization meeting on Friday, a move that would …

UK faces calls to drop opposition to patent-free Covid vaccines Read More »

Pfizer Covid-19 vaccine has 95% efficacy and is safe, further analysis shows

Among first 170 Covid cases in trial, eight had received vaccine and 162 were in placebo group Coronavirus – latest updates See all our coronavirus coverage The Pfizer/BioNTech vaccine against Covid-19 performs even better than previously thought, with 95% efficacy, equalling the early results from Moderna on Monday, according to an analysis of the final …

Pfizer Covid-19 vaccine has 95% efficacy and is safe, further analysis shows Read More »

Moderna vaccine’s effectiveness bodes well for Oxford/AstraZeneca jab

Phase 3 success rate of 95% for US firm’s treatment is promising for UK vaccine trial Coronavirus – latest updates See all our coronavirus coverage Hopes are rising for the Covid jab being developed by Oxford University, after Moderna became the second company to reveal impressive results from its vaccine trials. Interim results from phase …

Moderna vaccine’s effectiveness bodes well for Oxford/AstraZeneca jab Read More »

UK in ‘advanced discussions’ to buy Moderna Covid vaccine

Britain decided not to buy US vaccine and earliest it could be supplied to UK is spring 2021 Coronavirus – latest updates See all our coronavirus coverage The UK has not acquired the Moderna vaccine but is in “advanced discussions” to ensure British access, officials have said, while cautioning that no one in the UK …

UK in ‘advanced discussions’ to buy Moderna Covid vaccine Read More »

Moderna Covid vaccine candidate almost 95% effective, trials show

US-based biotech firm is latest to reveal impressive results from phase 3 trials of jab Coronavirus – latest updates See all our coronavirus coverage The race for a coronavirus vaccine has received another shot in the arm with the US biotech firm Moderna becoming the latest to reveal impressive results from phase 3 trials of …

Moderna Covid vaccine candidate almost 95% effective, trials show Read More »

BioNTech vaccine scientist says jab could halve Covid transmission

Uğur Şahin ‘very confident’ vaccine candidate developed with Pfizer will cause big reduction in cases Coronavirus – latest updates See all our coronavirus coverage The scientist behind the first potential Covid-19 vaccine to clear interim clinical trials says he is “very confident” the jab will reduce transmission of the disease, perhaps by 50%, resulting in …

BioNTech vaccine scientist says jab could halve Covid transmission Read More »

Vaccination hesitancy is about lack of trust. Compulsion is not the answer | Kenan Malik

Better to build social solidarity than to dismiss reluctance to be immunised as ignorance Coronavirus – latest updates See all our coronavirus coverage “If a strain as deadly as the 1918 influenza emerges and people’s hesitancy to get vaccinated remains at the level it is today, a debilitating and fatal disease will spread.” So wrote …

Vaccination hesitancy is about lack of trust. Compulsion is not the answer | Kenan Malik Read More »

Speedy work on Covid gives the vaccine industry a shot in the arm

Pfizer was first with the news, but biotech firms, governments, banks and NGOs are all involved in the search for a jab to prevent coronavirus infectionThe leading candidate to become the world’s first Covid-19 vaccine, developed by the US pharmaceutical company Pfizer and Germany’s BioNTech, had its genesis in late January 2020. Uğur Şahin, chief …

Speedy work on Covid gives the vaccine industry a shot in the arm Read More »

Scientist behind BioNTech/Pfizer vaccine says it can end pandemic

Exclusive: BioNTech’s CEO Uğur Şahin says he is confident vaccine can ‘bash the virus over the head’ Coronavirus – latest updates See all our coronavirus coverage The scientist behind the first Covid-19 vaccine to clear interim clinical trials says he is confident his product can “bash the virus over the head” and put an end …

Scientist behind BioNTech/Pfizer vaccine says it can end pandemic Read More »

The Covid vaccine will benefit humanity – we should all own the patent | Owen Jones

The pharmaceutical industry has long made exorbitant profits by free-riding on research carried out by the public sector Hooray for Pfizer! As news of a vaccine potentially offering 90% protection against Covid-19 offers a life raft for lockdown-weary humanity, perhaps those home-drawn posters on people’s windows thanking the NHS will soon be applauding big pharma …

The Covid vaccine will benefit humanity – we should all own the patent | Owen Jones Read More »

Why a Covid vaccine doesn’t mean the end of face masks yet | David Salisbury

Despite the Pfizer breakthrough, social distancing and remote working won’t disappear overnight Coronavirus – latest updates See all our coronavirus coverage The news this week that the Pfizer/BioNTech vaccine protected more than 90% of recipients is of huge importance. The vaccine efficacy is higher than we had hoped for. There appear to be no safety …

Why a Covid vaccine doesn’t mean the end of face masks yet | David Salisbury Read More »

Where will poorer countries stand in the queue for a Covid-19 vaccine? | Clare Wenham and Mark Eccleston-Turner

The lion’s share of the potential Pfizer vaccine is already claimed by high-income nations The news that joint efforts by the US pharmaceutical company Pfizer and the German biotech company BioNtech have produced a vaccine that is 90% effective at protecting people from Covid-19 has been understandably applauded – in spite of the caveats. Pfizer …

Where will poorer countries stand in the queue for a Covid-19 vaccine? | Clare Wenham and Mark Eccleston-Turner Read More »

FTSE 100 recovers to highest level since June after vaccine unveiled

Promising clinical data from Pfizer and BioNTech help the index to a £28bn one-day gain Optimism that a mass rollout of Covid-19 vaccines will lead to an economic recovery lifted stocks in London again on Tuesday, to their highest closing level in over four months. London’s FTSE 100 index of blue-chip shares rallied by nearly …

FTSE 100 recovers to highest level since June after vaccine unveiled Read More »

Pfizer and BioNTech could make $13bn from coronavirus vaccine

Johnson & Johnson and AstraZeneca pledged to make their vaccines available on a not-for-profit basis Coronavirus – latest updates See all our coronavirus coverage The US drugmaker Pfizer and the German biotech firm BioNTech stand to bring in nearly $13bn (£9.8bn) in global sales from their coronavirus vaccine next year, which will be evenly split …

Pfizer and BioNTech could make $13bn from coronavirus vaccine Read More »

Pfizer and BioNTech’s vaccine poses global logistics challenge

Europe and US create vast facilities for Covid-19 vaccine but poorer nations lack infrastructure say experts Coronavirus – latest updates See all our coronavirus coverage Two vast football-pitch-sized facilities equipped with hundreds of large freezers in Kalamazoo, Michigan, and Puurs, Belgium, will be the centres of the huge effort to ship the coronavirus vaccine developed …

Pfizer and BioNTech’s vaccine poses global logistics challenge Read More »

The Guardian view on the Covid vaccine breakthrough: making it work | Editorial

At last, there is hope of an end to this pandemic. Scientists appear to have performed an amazing feat, the rest of us must do our best too Medicine is only partly a matter of science; it is, very much, the business of people. The inspiring news that a Covid vaccine appears within reach, with …

The Guardian view on the Covid vaccine breakthrough: making it work | Editorial Read More »

Will enough people in the UK take the Covid-19 jab?

The UK usually has a high take-up for vaccines, experts say, but there are fears over misinformation and scepticism Coronavirus: anti-vaxxers seek to discredit Pfizer’s vaccine Coronavirus – latest updates See all our coronavirus coverage The spread of scepticism and misinformation about coronavirus and the development of a vaccine for it has raised questions about …

Will enough people in the UK take the Covid-19 jab? Read More »

Cautious optimism over Covid-19 vaccine trials | Letters

Readers respond to news that an interim analysis has shown Pfizer/BioNTech’s vaccine candidate was 90% effective in protecting people from transmission of the virus in global trials The media have been awash with stories about the apparent success of the Pfizer Covid vaccine following the publication of preliminary trial outcomes (Hopes rise for end of …

Cautious optimism over Covid-19 vaccine trials | Letters Read More »

6 key questions about the Pfizer/BioNTech Covid-19 vaccine

There are grounds for optimism but also several unknowns around this coronavirus vaccine Coronavirus – latest updates See all our coronavirus coverage Hopes that the end of the coronavirus pandemic has become nearer have soared after the news that a coronavirus vaccine was found to be 90% effective in global trials. Although there is definite …

6 key questions about the Pfizer/BioNTech Covid-19 vaccine Read More »

Despite the fine print, we can still feel optimistic about a Covid vaccine | Charlotte Summers

Pfizer’s preliminary results are a huge development, although hurdles still lie ahead Dr Charlotte Summers is a lecturer in intensive care medicine at the University of Cambridge Coronavirus – latest updates We could all do with some good news right now. After a long and difficult year of multiple lockdowns and numerous sacrifices, the announcement …

Despite the fine print, we can still feel optimistic about a Covid vaccine | Charlotte Summers Read More »

BioNTech’s Covid vaccine: a shot in the arm for Germany’s Turkish community

Couple who set up and run firm are children of long-maligned ‘guest workers’ from Turkey Coronavirus – latest updates See all our coronavirus coverage When the German biotechnology company BioNTech picked a street called An der Goldgrube or At the Goldmine in the western city of Mainz for its headquarters, the couple behind it could …

BioNTech’s Covid vaccine: a shot in the arm for Germany’s Turkish community Read More »

What has Pfizer’s Covid vaccine trial found and is this a breakthrough?

Early results from phase 3 trial look promising but there are still many questions to be answered Coronavirus – latest updates See all our coronavirus coverage Pfizer and the German biotech company Biontech said on Monday that they had had encouraging early results from a phase 3 clinical trial of their coronavirus vaccine. The trial …

What has Pfizer’s Covid vaccine trial found and is this a breakthrough? Read More »

Oxford Covid vaccine works in all ages, trials suggest

Vaccine being trialled by Oxford University and AstraZeneca offers hope for all age groups Coronavirus – latest updates See all our coronavirus coverage One of the world’s leading Covid-19 experimental vaccines produces an immune response in both older and young adults, raising hopes of a path out of the gloom and economic destruction wrought by …

Oxford Covid vaccine works in all ages, trials suggest Read More »

NHS coronavirus tests threatened by Roche supply chain glitch

Pharmaceutical firm reports ‘significant drop in processing capacity’ of reagents, kits and swabs Coronavirus – latest updates See all our coronavirus coverage Concerns have been raised over the supply of vital testing materials for a range of conditions, including Covid-19, following a supply chain problem with the pharmaceutical company Roche. On Tuesday, Roche said it …

NHS coronavirus tests threatened by Roche supply chain glitch Read More »

Trump’s steroid Covid treatment adds to confusion over health

Dexamethasone ‘normally reserved for people going into respiratory failure’, says expert Trump coronavirus treatment – live updates The latest intervention from Donald Trump’s medical team has been to put the president on dexamethasone, a steroid that is proven, thanks to the UK’s Recovery trial, to benefit Covid-19 patients who are having breathing difficulties. But the …

Trump’s steroid Covid treatment adds to confusion over health Read More »

Anti-Covid treatments being given to Trump are still unproven, say experts

Neither remdesivir nor REGN-COV2 have completed large-scale randomised trials, say UK scientists Coronavirus – latest updates See all our coronavirus coverage Scientists still lack conclusive proof that the two anti-Covid drugs given to Donald Trump are clinically effective. UK researchers point out that both medicines – remdesivir and REGN-COV2 – have still to complete the …

Anti-Covid treatments being given to Trump are still unproven, say experts Read More »

UK doing more than most to help poor get Covid vaccine, study finds

Campaign scoring countries for global access efforts calls for more British transparency Coronavirus – latest updates See all our coronavirus coverage The UK is doing more than most countries to support access to Covid vaccines for the poorest populations in the world, but it is not transparent enough about the deals it is doing at …

UK doing more than most to help poor get Covid vaccine, study finds Read More »

Show more empathy to boost confidence in vaccines, scientists told

Expert behind vaccine confidence report points to halting of Oxford Covid trial as example Doctors and scientists need to show more empathy towards volunteers in coronavirus vaccine trials who fall ill if the public is to have full confidence in the safety of the vaccines being developed, say experts. The temporary halting of the Oxford …

Show more empathy to boost confidence in vaccines, scientists told Read More »

Oxford Covid-19 vaccine is still possible this year, says AstraZeneca chief

Pharmaceutical firm’s boss says 2020 deadline possible if regulators move fast Coronavirus – latest updates See all our coronavirus coverage AstraZeneca’s coronavirus vaccine could still be available by the end of the year, or early next year, according to the company’s chief executive, Pascal Soriot, despite clinical trials being paused after a volunteer fell ill. …

Oxford Covid-19 vaccine is still possible this year, says AstraZeneca chief Read More »

Oxford Covid vaccine trial suspension: what happens next?

Tests have been paused after a UK volunteer became ill. How will it affect the search for a cure? The AstraZeneca vaccine trial has been paused – should we be worried? Coronavirus – latest updates See all our coronavirus coverage One of the volunteers in the UK has become ill and it is crucial that …

Oxford Covid vaccine trial suspension: what happens next? Read More »

The Oxford University AstraZeneca Covid-19 vaccine trial has been paused – should we be worried?

Is this the end for hopes of an early breakthrough in the race to find a coronavirus drug? The halt in development of the University of Oxford’s Covid-19 vaccine due to a possible adverse reaction in a trial participant has triggered fears of a delay in finding a solution to coronavirus restrictions. A spokesman for …

The Oxford University AstraZeneca Covid-19 vaccine trial has been paused – should we be worried? Read More »

Oleandrin: Trump allies pitch extract from poisonous plant to fight Covid

Experts raise concern over compound that has not been proven safe but could reach public as dietary supplement Allies of Donald Trump have promoted a plant extract called oleandrin to people seeking to ward off Covid-19. The plant the extract is derived from, oleander, is poisonous and there is no proof the compound is either …

Oleandrin: Trump allies pitch extract from poisonous plant to fight Covid Read More »

AstraZeneca starts Covid-19 antibody drug trial in UK

Volunteers are receiving doses of drug, which has potential both as a vaccine and a treatment Coronavirus – latest updates See all our coronavirus coverage The pharmaceutical group AstraZeneca has started a clinical trial of a drug to help prevent and treat Covid-19, with the first volunteers already receiving doses. The company, which is separately …

AstraZeneca starts Covid-19 antibody drug trial in UK Read More »

Six of the most promising treatments for Covid-19 so far

While a cure-all drug or therapy is a long way off, there have been some breakthroughs Many different drugs and therapies are being trialled and used on patients with Covid-19. There are some positive results, which may be beginning to bring the hospital death toll down, but there is still a long way to go …

Six of the most promising treatments for Covid-19 so far Read More »

Oxford University Covid-19 vaccine firm denies Trump talks

AstraZeneca says it has not discussed ‘emergency use authorisation’ with the US Coronavirus – latest updates See all our coronavirus coverage The company manufacturing the Oxford University coronavirus vaccine has denied it is in talks with the Trump administration about fast-tracking its vaccine for emergency use ahead of November’s presidential elections. With both Russia and …

Oxford University Covid-19 vaccine firm denies Trump talks Read More »

Honey better treatment for coughs and colds than antibiotics, study claims

Research suggests honey also more effective than many over-the-counter medicines Honey may be better than conventional treatments for coughs, blocked noses and sore throats, researchers have said. The substance is cheap, readily available, and has virtually no side-effects. Doctors can recommend it as a suitable alternative to antibiotics, which are often prescribed for such infections, …

Honey better treatment for coughs and colds than antibiotics, study claims Read More »

UK agrees deals for 90m doses of two potential coronavirus vaccines

Government secures early access to those being developed by Novavax and Janssen Coronavirus – latest updates See all our coronavirus coverage The UK government has reached agreements it says will give British citizens early access to 90m doses of two more potential Covid-19 vaccines. The vaccines are being developed by the US biotech company Novavax …

UK agrees deals for 90m doses of two potential coronavirus vaccines Read More »

The Guardian view on Brexit bureaucracy: tied up in red tape | Editorial

Businesses already struggling with the fallout from Covid-19 will be forced to deal with a mountain of new bureaucracy in the middle of a deep recession The government did not quite achieve the Brexit breakthrough it was seeking on Friday, when there was hope that a fast-tracked trade agreement with Japan might be reached. But …

The Guardian view on Brexit bureaucracy: tied up in red tape | Editorial Read More »

Australia experiencing critical shortage of antidepressants, contraceptives and HRT

Reasons for shortages are often unclear and substitutes, which are not subsidised by PBS, are prohibitively expensive Australia is experiencing a critical shortage of key drugs including antidepressants, contraceptives and hormone replacement therapies, a situation that experts say highlights systemic problems with medicine supply in the country. Most of the shortages appear unrelated to coronavirus …

Australia experiencing critical shortage of antidepressants, contraceptives and HRT Read More »

Covid-19: Gilead Sciences urged to study drug that showed promise with cats

Activists accuse company of pushing remdesivir to boost profit GS-441524 has been used to treat a coronavirus in cats Coronavirus – latest global updates Activists are calling on the pharmaceutical firm Gilead Sciences to study a drug for the treatment of Covid-19 that showed promise in curing cats of a coronavirus. The drug, called GS-441524, …

Covid-19: Gilead Sciences urged to study drug that showed promise with cats Read More »

AstraZeneca signs deal worth up to £4.7bn for cancer treatment

Pharmaceuticals company buys global rights to new technology from Japan’s Daiichi Sankyo Drugmaker AstraZeneca could pay up to $6bn (£4.7bn) for the global rights to a new Japanese cancer treatment. The Anglo-Swedish pharmaceutical company said it would pay $1bn (£800m) up front to its partner Daiichi Sankyo. Related: Covid-19 is Big Pharma’s chance to impress. …

AstraZeneca signs deal worth up to £4.7bn for cancer treatment Read More »

Covid-19 is Big Pharma’s chance to impress. But who’ll do best?

AstraZeneca and GSK both release results this week. But picking winners in the sector may be complicated It was the press announcement heard around the world: a potential Covid-19 vaccine from the University of Oxford and pharmaceutical company AstraZeneca had not only been “tolerated” by patients, but “generated robust immune responses against the Sars-CoV-2 virus …

Covid-19 is Big Pharma’s chance to impress. But who’ll do best? Read More »

‘Major’ breakthrough in Covid-19 drug makes UK professors millionaires

Synairgen’s share price rises 540% on morning of news of successful drugs trial Coronavirus – latest updates See all our coronavirus coverage Three professors at the University of Southampton school of medicine have this week made a “major breakthrough” in the treatment of coronavirus patients and become paper millionaires at the same time. Almost two …

‘Major’ breakthrough in Covid-19 drug makes UK professors millionaires Read More »

The world needs a ‘people’s vaccine’ for coronavirus, not a big-pharma monopoly | Helen Clark and Winnie Byanyima

AstraZeneca and others should not own a lucrative patent on a medicine that is needed by poor as well as rich nations • See all our coronavirus coverage • Helen Clark is a former prime minister of New Zealand and Winnie Byanyima is UN undersecretary general To bring an end to the pandemic, the world …

The world needs a ‘people’s vaccine’ for coronavirus, not a big-pharma monopoly | Helen Clark and Winnie Byanyima Read More »

WHO says trials show malaria and HIV drugs don’t cut Covid-19 hospital deaths

Hydroxychloroquine and lopinavir/ritonavir not found to help patients in hospital Coronavirus – latest updates See all our coronavirus coverage The World Health Organization (WHO) said on Saturday that it was discontinuing its trials of the malaria drug hydroxychloroquine and combination HIV drug lopinavir/ritonavir for patients in hospital with Covid-19 after they failed to reduce mortality. …

WHO says trials show malaria and HIV drugs don’t cut Covid-19 hospital deaths

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Oxford offers best hope for Covid-19 vaccine this year, MPs told

University is leading rivals but first drugs may not work fully, says vaccine taskforce chair Coronavirus – latest updates See all our coronavirus coverage Oxford University is leading the world in developing a vaccine against Covid-19 and offers the best chance of having something protective against the virus as we go into winter, MPs have …

Oxford offers best hope for Covid-19 vaccine this year, MPs told Read More »

US secures world stock of key Covid-19 drug remdesivir

No other country will be able to buy remdesivir, which can help recovery from Covid-19, for next three months at least Coronavirus – latest US updates Coronavirus – latest updates See all our coronavirus coverage The US has bought up virtually all the stocks for the next three months of one of the two drugs …

US secures world stock of key Covid-19 drug remdesivir Read More »

I believe Roundup gave me cancer. The Monsanto settlement is a slap in the face | Christine Sheppard

I have to inject myself with needles just to stay alive. Still, Bayer will continue to sell Roundup, and refused to label it as carcinogenic Last Wednesday was my 71st birthday, a low-key celebration in these Covid-19 times. Then I heard the news that the pharmaceutical conglomerate Bayer has offered a settlement to resolve several …

I believe Roundup gave me cancer. The Monsanto settlement is a slap in the face | Christine Sheppard Read More »

How will the world’s poorest people get a coronavirus vaccine? | Achal Prabhala and Kate Elder

Rich countries’ governments are putting all their trust in a marriage of markets and philanthropy called Gavi Vaccines for Covid-19 are coming. Billions of dollars are flowing in, over 100 efforts are under way, and at least 13 leading candidates are already being tested on humans. But how will these vaccines reach the poorest people …

How will the world’s poorest people get a coronavirus vaccine? | Achal Prabhala and Kate Elder

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‘The wondrous map’: how unlocking human DNA changed the course of science

Thanks to the success of the Human Genome Project, 20 years ago this week, scientists can track biology and disease at a molecular level Twenty years ago this week, an international group of scientists announced it had put together the first genetic blueprint of a human being. After 10 years of effort, the team – …

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Demand for flu vaccine soars as countries plan for second Covid-19 wave

Manufacturers warn they will struggle to meet demand as governments seek to ease pressure on health services Coronavirus – latest updates See all our coronavirus coverage Fears of a second wave of coronavirus have sparked a global scramble for influenza shots from countries that hope to vaccinate great swathes of the population to reduce pressure …

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The Lancet’s editor: ‘The UK’s response to coronavirus is the greatest science policy failure for a generation’

Richard Horton does not hold back in his criticism of the UK’s response to the pandemic and the medical establishment’s part in backing fatal government decisions Coronavirus – latest updates See all our coronavirus coverage There is a school of thought that says now is not the time to criticise the government and its scientific …

The Lancet’s editor: ‘The UK’s response to coronavirus is the greatest science policy failure for a generation’

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