Category: dementia

  • When It Comes to Digital Health, Experience Is Everything

    Aniket Singh Rajput, Founder and CEO of Neuroglee Thanks to COVID-19 and numerous other factors, the adoption of digital health technologies used by patients in the home has skyrocketed. Accenture reported in 2021, for example, that remote patient monitoring technology adoption tripled among patients. Whether it is streaming video telehealth appointments with a provider, a […]

  • Eisai’s brain health tool NouKNOW used in Tokyo dementia project

    Eisai’s digital tool to allow self-assessment of cognitive performance – NouKNOW – will be used in a Japanese project aimed at improving the management of dementia. The smartphone app – which uses a cognition-checking algorithm developed by Australian digital health company Cogstate – will be deployed in Bunkyo City, Tokyo in a dementia monitoring programme. […]

  • Single MRI-based brain scan could diagnose Alzheimer’s disease, says study

    Alzheimer’s disease could be diagnosed from a single MRI brain scan, according to a new study by Imperial College London. Using machine learning technology, researchers were able to examine structural features of the brain, including regions that are not traditionally associated with Alzheimer’s. The simplicity of this process, scientists suggest, could aid clinicians in identifying […]

  • 3 Ways Health Plans Can Improve Sleep Health for their Members

    Dr. Melissa Lim, Chief Medical Officer at Somnology Getting a good night’s sleep should have nothing to do with having a great health plan — but it often does.  While some individuals can improve their sleep by making small changes, many who suffer from serious, chronic sleep disorders need a higher level of care and […]

  • Cumulus puts its digital biomarkers for CNS diseases to the test

    Cumulus Neuroscience has started a pair of clinical trials to gauge the value of a panel of physiological and digital biomarkers in tracking the course of neurodegenerative diseases, including Alzheimer’s. The hope is that the toolkit will improve on current measurement tools for dementia and other neurological conditions that have serious limitations, according to the […]

  • Watch: Seniors Share How They’ve Made It Through the Pandemic

    Too often the voices of older people are not heard. Judith Graham, KHN’s Navigating Aging columnist, invited nine seniors from across the country to talk candidly about their highs and lows as they enter Year 3 of the pandemic, with lives reordered by risk and restriction.  How have people handled persistent stress? How have their […]

  • Neuro-focused Arkuda raises $64M as dementia drug moves closer to the clinic

    Eli Lilly is among the new investors joining the Series B round of Arkuda Therapeutics, a biotech developing a drug to treat a rare, inherited form of dementia. If the biotech’s approach works, it could also have applications in other neurodegenerative conditions such as Alzheimer’s and Parkinson’s.

  • Preventing Alzheimer’s Disease with Diet

    What evidence is there that our meat-sweet diets play a cause-and-effect role in dementia? What is behind the dramatic increase in dementia in Japan over recent decades? As you can see at the start of my video How to Prevent Alzheimer’s with Diet, rates have climbed significantly. Is it due to rising obesity rates or […]

  • KHN’s ‘What the Health?’: Dealing With Drug Prices

    Can’t see the audio player? Click here to listen on Acast. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. Medicare officials have preliminarily decided to restrict reimbursement for Aduhelm, the controversial Alzheimer’s drug, to only patients participating in approved clinical trials. The FDA approved the drug […]

  • Digital health’s ‘wow factor’ should focus on the patient

    While the era of using digital health tools to manage MCI and perhaps prevent greater cognitive decline is just beginning, it is a promising new therapeutic direction for a very complex condition. The more these solutions are developed and studied, it seems clear, however, that the most effective technology will be the systems that individuals […]

  • Wartime Trauma Hits Close to Home for Scholar of Dementia

    Oanh Meyer was a postdoctoral fellow studying the experiences of caregivers for those with dementia in 2012 when her research took a very personal turn. That year, her mother, a Vietnamese immigrant, began to show signs of dementia and paranoia that seemed to be linked to the trauma she had suffered during the long war […]

  • When the Eye on Older Patients Is a Camera

    In the middle of a rainy Michigan night, 88-year-old Dian Wurdock walked out the front door of her son’s home in Grand Rapids, barefoot and coatless. Her destination was unknown even to herself. Wurdock was several years into a dementia diagnosis that turned out to be Alzheimer’s disease. By luck, her son woke up and […]

  • Real-world evidence and qualitative research: the ELICIT podcast

    In the first episode of the ELICIT podcast, a new series produced in partnership with Cerner Enviza, the speakers discuss qualitative real-world evidence and a unique dementia project from Singapore. First, they look at why qualitative real-world evidence is important to pharma, what the criteria is for good qualitative research and why stakeholder preference studies […]

  • FDA clears AI-powered digital test for early dementia

    The FDA has approved an artificial intelligence-based test for early detection of dementia that can be carried out on an iPad in five minutes. The CognICA Integrated Cognitive Assessment (ICA) test developed by London, UK-based company Cognetivity Neurosciences has been approved by the FDA as an alternative to traditional pen-and-paper tests with some key advantages, […]

  • Alzheimer’s Drug Targets People With Mild Cognitive Impairment. What Does That Mean?

    The approval of a controversial new drug for Alzheimer’s disease, Aduhelm, is shining a spotlight on mild cognitive impairment — problems with memory, attention, language or other cognitive tasks that exceed changes expected with normal aging. After initially indicating that Aduhelm could be prescribed to anyone with dementia, the Food and Drug Administration now specifies […]

  • Startup Neuroglee raises $10m for virtual neurology clinics

    A digital health company focusing on neurodegenerative disorders – Neuroglee Therapeutics – has raised $10 million in first-round funding to roll out a virtual neurology clinics for people with cognitive problems caused by dementia. The Singapore startup, which is partnering with the Mayo Clinic on the clinics, said the cash injection will also go towards […]

  • Cambridge team says AI could diagnose dementia with one scan

    Researchers at Cambridge University in the UK are trialling an artificial intelligence system that they think could spot the signs of dementia after a single brain scan. The team – led by Prof Zoe Kourtzi of the university and Alan Turing Institute – told the BBC that the AI could make it possible to start […]

  • Doctores sopesan pros y contras de recetar la nueva droga para el Alzheimer

    Mientras médicos y expertos en políticas de salud debaten los méritos de Aduhelm, el primer fármaco para el Alzheimer aprobado en 18 años, los pacientes simplemente quieren saber: “¿me ayudará?”. Los médicos no tienen una respuesta definitiva. “En cada persona, será absolutamente imposible de predecir”, dijo el doctor Allan Levey, director del Centro de Investigación […]

  • Doctors Weigh Pros and Cons of Prescribing Hot-Button Alzheimer’s Drug

    As physicians and health policy experts debate the merits of Aduhelm, the first new drug for Alzheimer’s disease approved in 18 years, patients want to know: “Will this medication help me — and how much?” Doctors explaining the pros and cons of Aduhelm won’t have a definitive answer. “On an individual basis, it will be […]

  • Violent Colorado Arrest Puts Spotlight on How Police Treat Disabled People

    Nearly a year after police officers in Loveland, Colorado, injured an elderly woman with dementia and then laughed at footage of her arrest, two of those officers are facing criminal charges while the rest of the department undergoes additional training. The fallout has drawn national attention to a problem that experts say is widespread across […]

  • KHN’s ‘What the Health?’: Our 200th Episode!

    Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The Food and Drug Administration found itself in the hot seat this week when it approved a controversial new drug to treat Alzheimer’s disease with scant evidence […]

  • Saffron Put to the Test for Alzheimer’s

    The spice saffron is pitted head-to-head against the leading drug for severe Alzheimer’s disease. What’s the latest on treating memory disorders with the spice saffron? As I discuss in my video Saffron Versus Memantine (Namenda) for Alzheimer’s, “saffron has been widely used in the Persian traditional medicine for memory problems,” but it wasn’t put to […]

  • COVID-19’s collateral deaths

    People are not just dying from COVID, but the quarantine’s–while necessary–did exacerbate mental health issues for many individuals. This is especially true for individuals who suffer from Alzheimer’s and dementia. This American Life‘s had a recent episode showing how isolation likely accelerated the downward spiral of the narrator’s grandmother, who suffered from dementia. The Alzheimer’s […]

  • Trouble Managing Money May Be an Early Sign of Dementia

    After Maria Turner’s minivan was totaled in an accident a dozen years ago, she grew impatient waiting for the insurance company to process the claim. One night, she saw a red pickup truck on eBay for $20,000. She thought it was just what she needed. She clicked “buy it now” and went to bed. The […]

  • Can your typing patterns reveal if you have Alzheimer’s?

    The neuroQWERTY technology can analyse people’s typing for signs of motor conditions like Parkinson’s disease – and now the team behind it is looking to expand into the notoriously-difficult area of dementia. Teresa Arroyo-Gallego tells us about the science behind the technology and how the team hopes to reshape cognitive screening.  While many disease areas […]

  • Acadia puts blame on FDA as Nuplazid rejected for dementia

    Acadia Pharmaceuticals is butting heads with US regulators again, this time over the FDA’s decision to reject its Nuplazid (pimavanserin) for use in dementia-related psychosis (DRP) – with the company bemused by the agency’s apparent pivot on an agreed trial design.  The FDA has rejected the expansion of the drug – originally approved to treat […]

  • BioXcel’s BXCL501 Receives the US FDA’s Breakthrough Therapy Designation for Acute Treatment of Agitation Associated with Dementia

    Shots: The BTD is based on a P-Ib/II TRANQUILITY study assessing BXCL501 in patients with acute treatment of agitation associated with dementia, including AD The results demonstrated significant reductions in agitation measures @2hrs. post-dose with both 30 and 60 mcg doses as measured by multiple scales. The dose dependent response has the potential to support […]

  • How Artificial Intelligence Is Making Senior Care More Human

    Bent Philipson, Founder of Philosophy Care When it comes to skilled nursing facilities (SNFs) in particular and long-term care in general, a human-centered and empathetic approach is not only necessary, it’s obligatory. Putting the needs, constraints, and perspectives of patients first enhances the level of care we’re able to provide.  Perhaps ironically, it is the […]

  • If I Have Cancer, Dementia or MS, Should I Get the Covid Vaccine?

    As public demand grows for limited supplies of covid-19 vaccines, questions remain about the vaccines’ appropriateness for older adults with various illnesses. Among them are cancer patients receiving active treatment, dementia patients near the end of their lives and people with autoimmune conditions. Recently, a number of readers have asked me whether older relatives with […]

  • As Telehealth Surges, Are Seniors Being Left Behind?

    Anne Davis, Director of Quality Programs & Medicare Strategy at HMS A global health crisis has thrust us into a scenario in which lives quite literally depend on the ability to virtually connect. Telehealth has rapidly emerged as a vital tool, enabling continuity of care, allowing vulnerable individuals to access their physician from home, and […]

  • Eisai forges CNS alliance with UK’s Wren Therapeutics

    Japanese drugmaker Eisai has teamed up with UK biotech Wren Therapeutics on an R&D programme seeking drugs for neurodegenerative disorders. The two companies will focus their efforts on alpha-synuclein, a pathway that has been implicated in disorders such as dementia with Lewy bodies (DLB) and Parkinson’s disease (PD). DLB and PD are both so-called synucleinopathies, […]

  • Açaí vs. Wild Blueberries for Artery Function

    “Plant-based diets…have been found to reduce the risk of cardiovascular disease” and some of our other leading causes of death and disability. “Studies have shown that the longest living and least dementia-prone populations subsist on plant-based diets.” So why focus on açaí berries, just one plant, for brain health and performance? Well, “foods rich in […]

  • Topical Lemon Balm Lotion for Alzheimer’s

    Improving cognitive performance with aromatherapy in young, healthy volunteers is one thing, but how about where it really matters? As I discuss in my video Best Aromatherapy Herb for Alzheimer’s, a group of Japanese researchers had a pie-in-the-sky notion that certain smells could lead to “nerve rebirth” in Alzheimer’s patients. Twenty years ago, even simply […]

  • Recent Advances in Alzheimer’s Disease Prevention

    Recent Advances in Alzheimer’s Disease Prevention A prominent neurologist reviews what is known (and not known) about recent evidence-based advances in Alzheimer’s Disease prevention. The Doctor Weighs In

  • Pain-detecting tool for dementia patients rolls out in UK

    A smartphone-based app that uses facial analysis technology to spot chronic pain in people with dementia, called PainChek, is being rolled out in the UK by its Australian developer. The artificial intelligence-powered tool can help care workers and clinicians to identify and manage pain in patients with conditions like Alzheimer’s disease that can make it […]

  • Isolation, Disruption and Confusion: Coping With Dementia During a Pandemic

    GARDENA, Calif. — Daisy Conant, 91, thrives off routine. One of her favorites is reading the newspaper with her morning coffee. But, lately, the news surrounding the coronavirus pandemic has been more agitating than pleasurable. “We’re dropping like flies,” she said one recent morning, throwing her hands up. “She gets fearful,” explained her grandson Erik […]

  • High Blood Pressure May Lead to Low Brain Volume

    Having hypertension in midlife (ages 40 through 60) is associated with elevated risk of cognitive impairment and Alzheimer’s dementia later in life, even more so than having the so-called Alzheimer’s gene. “It is clear that cerebral vascular disease”—that is, hardening of the arteries inside our brain—“and cognitive decline travel hand in hand,” something I’ve addressed […]