Acadia Pharmaceuticals is butting heads with US regulators again, this time over the FDA’s decision to reject its Nuplazid (pimavanserin) for use in dementia-related psychosis (DRP) – with the company bemused by the agency’s apparent pivot on an agreed trial design. The FDA has rejected… Read More »Acadia puts blame on FDA as Nuplazid rejected for dementia
The FDA’s rejection of Nuplazid cited clinical trial results in subgroups of patients. Acadia Pharmaceuticals said the FDA’s decision goes against all feedback the company previously received and amounts to an incorrect way of evaluating dementia patients.
BioXcel’s BXCL501 Receives the US FDA’s Breakthrough Therapy Designation for Acute Treatment of Agitation Associated with Dementia
Shots: The BTD is based on a P-Ib/II TRANQUILITY study assessing BXCL501 in patients with acute treatment of agitation associated with dementia, including AD The results demonstrated significant reductions in agitation measures @2hrs. post-dose with both 30 and 60 mcg doses as measured by multiple… Read More »BioXcel’s BXCL501 Receives the US FDA’s Breakthrough Therapy Designation for Acute Treatment of Agitation Associated with Dementia
Bent Philipson, Founder of Philosophy Care When it comes to skilled nursing facilities (SNFs) in particular and long-term care in general, a human-centered and empathetic approach is not only necessary, it’s obligatory. Putting the needs, constraints, and perspectives of patients first enhances the level of… Read More »How Artificial Intelligence Is Making Senior Care More Human
This story also ran on St. Louis Post-Dispatch. It can be republished for free. Arthur Kelley could barely raise his voice above a whisper last fall when he told a nursing assistant he never wanted his wife, Maggie, to be alone. After almost 60 years… Read More »After Nearly 60 Years of Marriage, This Missouri Couple Stayed Together to the End
As public demand grows for limited supplies of covid-19 vaccines, questions remain about the vaccines’ appropriateness for older adults with various illnesses. Among them are cancer patients receiving active treatment, dementia patients near the end of their lives and people with autoimmune conditions. Recently, a… Read More »If I Have Cancer, Dementia or MS, Should I Get the Covid Vaccine?
Biogen plans to launch a virtual study with Apple this year to identify early signs of mild cognitive impairment. The study is expected to launch in the second half of 2021.
Anne Davis, Director of Quality Programs & Medicare Strategy at HMS A global health crisis has thrust us into a scenario in which lives quite literally depend on the ability to virtually connect. Telehealth has rapidly emerged as a vital tool, enabling continuity of care,… Read More »As Telehealth Surges, Are Seniors Being Left Behind?
Japanese drugmaker Eisai has teamed up with UK biotech Wren Therapeutics on an R&D programme seeking drugs for neurodegenerative disorders. The two companies will focus their efforts on alpha-synuclein, a pathway that has been implicated in disorders such as dementia with Lewy bodies (DLB) and… Read More »Eisai forges CNS alliance with UK’s Wren Therapeutics
“Plant-based diets…have been found to reduce the risk of cardiovascular disease” and some of our other leading causes of death and disability. “Studies have shown that the longest living and least dementia-prone populations subsist on plant-based diets.” So why focus on açaí berries, just one… Read More »Açaí vs. Wild Blueberries for Artery Function
Improving cognitive performance with aromatherapy in young, healthy volunteers is one thing, but how about where it really matters? As I discuss in my video Best Aromatherapy Herb for Alzheimer’s, a group of Japanese researchers had a pie-in-the-sky notion that certain smells could lead to… Read More »Topical Lemon Balm Lotion for Alzheimer’s
Recent Advances in Alzheimer’s Disease Prevention A prominent neurologist reviews what is known (and not known) about recent evidence-based advances in Alzheimer’s Disease prevention. The Doctor Weighs In
A smartphone-based app that uses facial analysis technology to spot chronic pain in people with dementia, called PainChek, is being rolled out in the UK by its Australian developer. The artificial intelligence-powered tool can help care workers and clinicians to identify and manage pain in… Read More »Pain-detecting tool for dementia patients rolls out in UK
GARDENA, Calif. — Daisy Conant, 91, thrives off routine. One of her favorites is reading the newspaper with her morning coffee. But, lately, the news surrounding the coronavirus pandemic has been more agitating than pleasurable. “We’re dropping like flies,” she said one recent morning, throwing… Read More »Isolation, Disruption and Confusion: Coping With Dementia During a Pandemic
Having hypertension in midlife (ages 40 through 60) is associated with elevated risk of cognitive impairment and Alzheimer’s dementia later in life, even more so than having the so-called Alzheimer’s gene. “It is clear that cerebral vascular disease”—that is, hardening of the arteries inside our… Read More »High Blood Pressure May Lead to Low Brain Volume