Nutrition

CMS grants quality reporting exceptions for facilities recovering from Hurricane Ida

The agency has granted certain Medicare quality reporting exceptions to healthcare facilities in areas of Louisiana, Mississippi, New York and New Jersey that were battered by Hurricane Ida. By providing the exceptions, CMS aims to enable facilities to direct their resources toward recovery.

Better late than never? Eczema drug now approved, Incyte says warning unwarranted

Atopic dermatitis patients now have a new option that comes as a topical cream. The FDA approved Incyte’s drug, Opzelura, as a treatment for the inflammatory skin condition, but the regulatory nod comes with a black box warning on the label that broadly covers the entire class of JAK inhibitors.

Vigeo Reports Completion of VT1021 in P-I/II Study for the Treatment of Recurrent Glioblastoma and Pancreatic Cancer

Shots: The P-I/II dose expansion studies evaluate the safety & preliminary anti-tumor efficacy of VT1021 as monothx. in patients with dose-escalation & expansion cohorts with rGBM & PC. The results of both studies are expected in Q4’21 In the rGBM expansion cohort, the therapy showed a complete tumor regression & PR, patients remain on trial …

Vigeo Reports Completion of VT1021 in P-I/II Study for the Treatment of Recurrent Glioblastoma and Pancreatic Cancer Read More »

Takeda Enters into an Exclusive License Agreement with Mirum to Develop and Commercialize Maralixibat for Rare Pediatric Liver Diseases in Japan

Shots: Takeda will lead the regulatory approval and commercialization of maralixibat in Japan & will also be responsible for the development, including conducting clinical studies in cholestatic indications The collaboration will utilize Takeda’s leadership in rare disease, gastroenterology, and hepatology to advance the product in Japan Mirum has submitted a maralixibat’s NDA to the US …

Takeda Enters into an Exclusive License Agreement with Mirum to Develop and Commercialize Maralixibat for Rare Pediatric Liver Diseases in Japan Read More »

Addressing the HIV epidemic in Eastern Europe and Central Asia

Working in partnership will be key, says Alex Kalomparis, vice president, public affairs, international at Gilead Sciences. 2021 marks 40 years since the first cases of HIV were reported. In that time, over 79 million people have been diagnosed with HIV, with more than 36 million dying from AIDS-related illnesses, more than any other infectious …

Addressing the HIV epidemic in Eastern Europe and Central Asia Read More »

Pressure Grows on U.S. Companies to Share Covid Vaccine Technology

Moderna accepted $2.5 billion in taxpayer money to develop its Covid-19 vaccine. But officials in the U.S. and overseas are having trouble persuading the company to license its technology.

Seagen and Genmab’s Tivdak (tisotumab vedotin-tftv) Receive the US FDA’s Accelerated Approval for the Treatment of Recurrent or Metastatic Cervical Cancer

Shots: The approval is based on the P-II innovaTV 204 clinical trials evaluating tisotumab vedotin in 101 patients with r/mCC who had received no more than two prior systemic regimens in the recurrent or metastatic setting, including one prior Pt-based CT regimen The results showed an ORR (24%) as assessed by IRC using RECIST v1.1 …

Seagen and Genmab’s Tivdak (tisotumab vedotin-tftv) Receive the US FDA’s Accelerated Approval for the Treatment of Recurrent or Metastatic Cervical Cancer Read More »

Seagen, Genmab antibody drug conjugate gets FDA approval in cervical cancer

The Seagen and Genmab antibody drug conjugate (ADC), named Tivdak, is approved to treat cases of cervical cancer that have returned or spread following treatment with chemotherapy. Tivdak is Seagen’s third ADC; for Genmab, the drug will become its first commercialized product.

Many Medicare Beneficiaries Face High Out-of-Pocket Costs for Dental and Hearing Care, Whether in Traditional Medicare or Medicare Advantage

Many Medicare beneficiaries face high annual out-of-pocket costs for dental and hearing care — services that generally aren’t covered in traditional Medicare, but typically are covered by Medicare Advantage plans though the scope and value of these benefits vary, finds a new KFF analysis. The analysis shows that, among beneficiaries who used each type of…More

Dental, Hearing, and Vision Costs and Coverage Among Medicare Beneficiaries in Traditional Medicare and Medicare Advantage

This analysis builds on our prior work – Medicare and Dental Coverage: A Closer Look – by analyzing hearing and vision use, out-of-pocket spending and cost-related barriers to care among Medicare beneficiaries as well as hearing and vision benefits in Medicare Advantage plans. It also incorporates top-level findings from the analysis of dental services to …

Dental, Hearing, and Vision Costs and Coverage Among Medicare Beneficiaries in Traditional Medicare and Medicare Advantage Read More »

90% of Women Appear Misinformed About Mammograms 

Most women are just being told what to do, rather than being given the facts needed to make a fully informed decision.   “Selling cancer screening can be easy,” begins an editorial in the Journal of the National Cancer Institute. “Induce fear by exaggerating risk. Offer hope by exaggerating the benefit of screening. And don’t mention harms [caused by the screening]. It is especially easy …

90% of Women Appear Misinformed About Mammograms  Read More »

FDA clears Seagen, Genmab’s Tivdak ADC for cervical cancer

Antibody-drug conjugate (ADC) specialist Seagen has claimed its fourth product approval in the US, getting the nod from the FDA for Tivdak as a second-line monotherapy for recurrent or metastatic cervical cancer. The accelerated approval for Tivdak (tisotumab vedotin) is for women whose cancer has progressed on or after first-line chemotherapy, according to the two …

FDA clears Seagen, Genmab’s Tivdak ADC for cervical cancer Read More »

Dentistas eliminan los problemas de las personas sin seguro ofreciéndoles ellos mismos planes

David White, dentista de Nevada, ha visto dientes enfermos y podridos en la boca de pacientes que habitualmente posponen sus chequeos y evitan procedimientos menores como empastes. Si bien la fobia dental es un factor, White dijo que la razón principal por la que las personas no se tratan es el costo. Para ayudar a …

Dentistas eliminan los problemas de las personas sin seguro ofreciéndoles ellos mismos planes Read More »

Peppermint Bark Quest Bar, Welcome Back!

The Peppermint Bark #QuestBar is back! 😍 One of your favorite seasonal flavors is AVAILABLE NOW for a limited time online & in stores at QuestNutrition.com, Target, Walmart, Vitamin Shoppe, Wegmans (Northeast, Southeast) Hy-Vee (Midwest), Giant Eagle (Northeast, Midwest), HEB (Texas) & your local health/nutrition stores nationwide. 🎃🍂 This bar […]

Merck Reports Results of Keytruda (pembrolizumab) in P-III KEYNOTE-826 Trial as 1L Treatment for Cervical Cancer

Shots: The P-III KEYNOTE-826 trial evaluates Merck’s Keytruda (200mg, IV, q3w for up to 35 cycles) + Pt-based CT vs PBO + CT with/out bevacizumab in 617 patients aged b/w 22- 82yrs. with persistent, recurrent, or metastatic cervical cancer The results showed a 33% reduction in the risk of death; m-OS (24.4 vs 16.5mos.), m-PFS …

Merck Reports Results of Keytruda (pembrolizumab) in P-III KEYNOTE-826 Trial as 1L Treatment for Cervical Cancer Read More »

EU panel rejects Pfizer’s tanezumab for osteoarthritis pain

Any lingering hope that Pfizer’s may finally get a regulatory approval for its nerve growth factor (NGF) inhibitor tanezumab looks to have been dashed after the EMA’s human medicines committee rejected the drug. A positive recommendation was already looking like a long shot for after FDA advisors voted 15 to one against approval of the …

EU panel rejects Pfizer’s tanezumab for osteoarthritis pain Read More »

Pumpkin Streusel Sweet Potato Boats using Pumpkin Pie Quest Bar!

We’re going to be honest with you: these were our first sweet potato boats – pumpkin streusel or otherwise. Now not only are we huge pumpkin streusel sweet potato boat fans, now we’re wondering how we managed to waste so many years not being on the sweet potato boat boat. […]

Pumpkin Pecan Cobbler with Pumpkin Pie Quest Bar!

We happen to think that cobbler is the quintessential autumn treat. Throw pumpkin and pecan into the recipe, and well…. let’s just say you’re checking a lot of our seasonal boxes: It’s nutty. It’s spicy. It’s pumpkin. It’s pecan. This one is also relatively simple to make using the Pumpkin […]

ESMO21: Roche’s giredestrant takes stage in battle of the oral SERDs

Roche has revealed the first phase 2 clinical data with giredestrant, one of a clutch of new selective oestrogen receptor degraders (SERDs) hoping to provide an oral alternative to AstraZeneca’s injectable Faslodex for breast cancer. The Swiss drugmaker presented results from its coopERA trial of giredestrant in post-menopausal women with hormone receptor (HR)-positive, HER2-negative early …

ESMO21: Roche’s giredestrant takes stage in battle of the oral SERDs Read More »

ESMO21: First combo data with Amgen’s Lumakras hit the mark in CRC

Amgen has made progress with its plans to expand the use of its first-in-class KRAS inhibitor Lumakras, reporting encouraging results when the drug is used alongside its EGFR drug Vectibix in colorectal cancer (CRC). The phase 2 study due to be reported at the ESMO cancer meeting – in patients KRAS G12c-mutated CRC – is …

ESMO21: First combo data with Amgen’s Lumakras hit the mark in CRC Read More »

Dentists Chip Away at Uninsured Problem by Offering Patients Membership Plans

Nevada dentist David White has seen diseased and rotted teeth in the mouths of patients who routinely put off checkups and avoided minor procedures such as fillings. While dental phobia is a factor, White said, the overriding reason people avoid treatment is cost. To help patients lacking dental insurance, White in 2019 started offering a …

Dentists Chip Away at Uninsured Problem by Offering Patients Membership Plans Read More »

KHN’s ‘What the Health?’: Much Ado About Drug Prices

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. Congressional Democrats are finding it harder to actually write legislation to lower drug prices than it is to make promises about it. But the drug price provisions of the $3.5 trillion social-spending bill …

KHN’s ‘What the Health?’: Much Ado About Drug Prices Read More »

Takeda therapy gets speedy FDA nod for lung cancers with rare genetic signature

Takeda Pharmaceutical drug mobocertinib was approved by the FDA to treat non-small cell lung cancer in patients whose tumors carry a rare genetic signature. With the approval, Takeda can offer an oral alternative to a recently approved Johnson & Johnson drug that targets the same mutation but is given as an infusion.

Lead Contamination in Calcium Supplements 

Do calcium citrate and calcium carbonate have as much lead as calcium supplements derived from dolomite and animal bone?  You may remember I’ve explored the role calcium supplements may play in reducing lead exposure during pregnancy and breastfeeding, but that assumes the supplements themselves are not contaminated. Supplements with lead?  It all started with an extraordinary case report published in 1977, entitled “Lead-Contaminated Health Food.” As I discuss in my video Lead in Calcium …

Lead Contamination in Calcium Supplements  Read More »

Dice’s IPO roll comes up with $204M for R&D of oral drugs to rival biologics

Dice Therapeutics raised $204 million from its IPO to support development of oral drugs that could compete against biologic drugs that are injected or infused. Also debuting on the public markets were Tyra Biosciences and Procept BioRobotics.

Lawsuit: Aetna fertility coverage policy “an illegal tax” on LGBTQ people

The lawsuit alleges that an Aetna policy discriminates against LGBTQ people by requiring them to pay thousands in out-of-pocket costs for fertility treatments before becoming eligible for coverage. Though Aetna has agreed to pay the costs incurred by the plaintiffs, the suit aims to strike down the policy as a whole.

Más de la mitad de los estados han revertido poderes de salud pública durante la pandemia

Motivados por votantes enojados por los cierres y los mandatos sobre el uso de máscaras durante la pandemia, legisladores republicanos en más de la mitad de los estados de EE.UU. están quitando los poderes que los funcionarios estatales y locales usan para proteger al público contra las enfermedades infecciosas. Una revisión de KHN encontró que, …

Más de la mitad de los estados han revertido poderes de salud pública durante la pandemia Read More »

Roche Collaborates with Temedica to Launch Brisa App for the Treatment of Multiple Sclerosis

Shots: The companies collaborated to launch a digital companion app i.e., Brisa to treat patients with MS. The app will be offered free of charge for users and motivates to change lifestyle in the long term The Brisa app is designed as an individual digital companion & will collect daily health data like activity, sleep, …

Roche Collaborates with Temedica to Launch Brisa App for the Treatment of Multiple Sclerosis Read More »

Phony Diagnoses Hide High Rates of Drugging at Nursing Homes

At least 21 percent of nursing home residents are on antipsychotic drugs, a Times investigation found.

Astellas Pharma reports fourth patient death in gene therapy clinical trial

The death occurred less than two weeks after Astellas Pharma reported that the patient developed liver problems after being dosed with the experimental gene therapy for a rare neuromuscular disorder. Astellas said the cause of death is still under investigation, and the FDA has placed a clinical hold on the study.

The Effects of Nutritional Yeast for Cancer 

How can the beta glucan fiber in brewer’s, baker’s, and nutritional yeast improve wound healing and, potentially, anti-cancer immunity?  My video Benefits of Nutritional Yeast for Cancer opens with an image of an article titled “The Treatment of Inoperable Cancer.” It noted that “200 years ago it was observed that a certain number of malignant growths disappeared after an attack of erysipelas [a type of …

The Effects of Nutritional Yeast for Cancer  Read More »

ONO and BMS Report Submission of sBLA for Opdivo (nivolumab) + Yervoy (ipilimumab) as 1L Treatment of Unresectable Advanced or Recurrent ESCC in Japan

Shots: The application is based on P-III CheckMate -648 study evaluating Opdivo (3mg/kg, q2w, IV) + Yervoy (1mg/kg, q6w up to 24mos.) or Opdivo + CT vs CT alone in patients with unresectable advanced or recurrent ESCC The results demonstrated an improvement in OS at pre-specified interim analysis in patients with tumor cell PD-L1 expression …

ONO and BMS Report Submission of sBLA for Opdivo (nivolumab) + Yervoy (ipilimumab) as 1L Treatment of Unresectable Advanced or Recurrent ESCC in Japan Read More »

Evidence lacking for AI-based breast cancer screening  

A review of 12 studies about AI systems used to screen patients for breast cancer found that they lacked evidence to prove that they would work well in a clinical setting. Researchers highlighted concerns about study quality, including the fact that all of the studies were retrospective and many of them had a high risk …

Evidence lacking for AI-based breast cancer screening   Read More »

Peanut Butter Candy Bites Cereal Bars using Quest Candy Bites Recipe

We know that every Questified recipe seems like some kind of amazing life hack, but these peanut butter candy bites cereal bars are truly next-level. They’re crunchy and sweet, and they’re cereal bars so they’re technically for breakfast. But let’s be honest, we’ll be reaching for these morning, noon, and […]

Pumpkin Pie Quest Bar Is Back For Fall!

Hello, Gourd-geous! The Pumpkin Pie Quest Bar is back! AVAILABLE NOW for a limited time online & in stores at QuestNutrition.com, Amazon, Target, Walmart, Vitamin Shoppe, Wegmans (Northeast, Southeast) Hy-Vee (Midwest), Giant Eagle (Northeast, Midwest), HEB (Texas) & your local health/nutrition stores nationwide. 🎃🍂 Your favorite seasonal flavor has a […]

Air-Fried Avocado Tacos using Quest Protein Chips!

We’re hooked on these air-fried avocado tacos, and we place the blame squarely on how nicely the taste of crushed Quest Ranch Tortilla Chips goes with avocado and tomato. We were already mildly obsessed with cilantro and the concept of air-frying, so consider these tacos a permanent fixture on our […]

Digital health approach improves neurosurgery care, says study

Deployment of digital health technologies during the pandemic improved patient satisfaction, expanded the delivery of care and augmented training of staff at a leading neurosurgery provider in the US, according to a new study. Faced with the disruption caused by the COVID-19 crisis, Cleveland Clinic centres implemented a number telehealth and audio-visual technologies to compensate …

Digital health approach improves neurosurgery care, says study Read More »

Journalists Explain Ramifications of Theranos Trial and Texas’ New Abortion Law

KHN Editor-in-Chief Elisabeth Rosenthal discussed health tech and the start of the fraud trial of Elizabeth Holmes, who founded the biological screening company Theranos, on WGN’s “The John Williams Show” on Wednesday. Click here to hear Rosenthal on “The John Williams Show” KHN senior correspondent Julie Appleby discussed abortion law in Texas, covid-19 and vaccination …

Journalists Explain Ramifications of Theranos Trial and Texas’ New Abortion Law Read More »

Digital health companies debate: how much can we scale the human element in mental health?

Four digital health leaders debated the role of self care apps, coaches and therapists in mental health during a panel at “What’s Next in Health Care?” While some touted the broader reach of self-guided treatments, others noted it was critical to have a therapist available for patients who need it.  

FDA warns Kaleido Bio to test its Covid-19 candidate as a drug, not a medical food

The FDA issued a warning letter to Kaleido Biosciences alleging the company tested its experimental microbiome product in Covid-19 patients without submitting a formal clinical trial application. Kaleido claims the filing was not required because the product is a medical food, but the regulator doesn’t buy that argument.

BioNTech to seek approval for Covid jabs for younger children

Company behind Pfizer vaccine expected to file results of trial of five- to 11-year-olds with regulator soon Coronavirus – latest updates See all our coronavirus coverage The German company BioNTech, which developed the Pfizer vaccine, expects to seek approval from regulators for Covid jabs suited for younger children as early as mid-October, its founders have …

BioNTech to seek approval for Covid jabs for younger children Read More »

Startup Neuroglee raises $10m for virtual neurology clinics

A digital health company focusing on neurodegenerative disorders – Neuroglee Therapeutics – has raised $10 million in first-round funding to roll out a virtual neurology clinics for people with cognitive problems caused by dementia. The Singapore startup, which is partnering with the Mayo Clinic on the clinics, said the cash injection will also go towards …

Startup Neuroglee raises $10m for virtual neurology clinics Read More »

NHS fast tracks access to Amgen’s just-approved KRAS cancer drug

Amgen’s first-in-class KRAS inhibitor Lumykras has been approved in Great Britain and arrives already armed with an agreement to allow early access while its cost-effectiveness is appraised by NICE. The MHRA has approved Lumykras (sotorasib) for patients with previously treated locally advanced or metastatic non-small cell lung cancer (NSCLC) with the KRAS G12C mutation, and …

NHS fast tracks access to Amgen’s just-approved KRAS cancer drug Read More »

Anxiety, Worry or Fear? Disappointment, Grief or Depression?

By HANS DUVEFELT Especially in these strange and uncertain times, many people feel uneasy. Some of them come to us with concerns over their state of mind. In primary care, our job is in large part to perform triage. We strive to identify patients who need referral, medication or further evaluation. We also strive, or …

Anxiety, Worry or Fear? Disappointment, Grief or Depression? Read More »

Does Coconut Oil Help with Abdominal Fat?

What does a review of the evidence on the effects of coconut oil on weight loss and belly fat find?  I begin my video Flashback Friday: Coconut Oil and Abdominal Fat with a popular infographic that surprised me by showing that, evidently, there is promising evidence that coconut oil could help with obesity. Well, if you fill the stomachs of rats with purified medium-chain fatty acids, one component of coconut oil, they end …

Does Coconut Oil Help with Abdominal Fat? Read More »

AstraZeneca and Hutchmed Initiate P-III SANOVO Trial for Orpathys (savolitinib) + Tagrisso (osimertinib) as a 1L Therapy for Non-small Cell Lung Cancer in China

Shots: The companies initiate P-III SANOVO study to evaluates the efficacy & safety of Orpathys in combination with AstraZeneca’s Tagrisso (irreversible EGFR TKI) vs Tagrisso alone in patients with NSCLC whose tumors harbor EGFR mutation and overexpress MET. The first patient was dosed on Sept 7, 2021 The 1EPs of the study is m-PFS as …

AstraZeneca and Hutchmed Initiate P-III SANOVO Trial for Orpathys (savolitinib) + Tagrisso (osimertinib) as a 1L Therapy for Non-small Cell Lung Cancer in China Read More »

Mayo Clinic, Google develop AI algorithm to enhance electrical brain stimulation

The algorithm maps interactions between different areas of the brain, which can help guide the placement of electrodes for stimulating devices to treat brain diseases, like epilepsy, and movement disorders.

AM-Pharma Enters into an Exclusive License Agreement with Kyowa Kirin to Commercialize Ilofotase Alfa in Japan

Shots: AM-Pharma to receive $23.6M up front, $35.4M in milestones before regulatory submission and ~$230.4M upon submission, NHI price listing & sales milestone along with royalties on sales and a drug supply fee Kyowa Kirin to get the exclusive right to develop and commercialize ilofotase alfa in Japan. Ilofotase alfa is currently being evaluated in …

AM-Pharma Enters into an Exclusive License Agreement with Kyowa Kirin to Commercialize Ilofotase Alfa in Japan Read More »

AI ‘could help diagnose lung cancer a year earlier’

An artificial intelligence algorithm was able to detect signs of lung cancer on CT scans a year earlier than with traditional methods, according to a new study. CT (computed tomography) scans are already used to spot signs of lung tumours, followed by a biopsy or surgery to confirm whether the tumour is malignant, according to …

AI ‘could help diagnose lung cancer a year earlier’ Read More »

Roche bets $300M on Adaptimmune tech for off-the-shelf cell therapies for cancer

Roche is partnering with Adaptimmune Therapeutics to develop allogeneic cell therapies based on Adaptimmune’s technology. In addition to these “off-the-shelf” products, the partners will also develop a personalized allogeneic cell therapy designed specifically for a patient’s cancer.

Countering Stress-Induced Immune Suppression with Diet

How might we improve immune function in children and adults under physical or psychological stress?  “Natural immunomodulators”—compounds that might regulate our immune systems naturally—”are getting more and more popular. The popularity, however, often brings over-optimistic claims and mediocre effects.” Such mythical beasts have been sought after for centuries. The current market is full of all sorts of supplements “promising the golden fleece”—inexpensive and without side effects, yet …

Countering Stress-Induced Immune Suppression with Diet Read More »

JW’s Relmacabtagene Autoleucel Receives the NMPA’s Approval for the Treatment of R/R Large B-Cell Lymphoma in China

Shots: The approval is based on a RELIANCE study that evaluates efficacy & safety of relma-cel in 59 patients with r/r LBCL who had failed at least 2L of therapy, including CD20 agent & anthracycline & patients continue to be monitored for 2+ yrs. The results showed the high rates of durable disease response & …

JW’s Relmacabtagene Autoleucel Receives the NMPA’s Approval for the Treatment of R/R Large B-Cell Lymphoma in China Read More »

Prof Nigel Osborne: Science is catching up with ‘medical music’

The internationally recognised composer, peace worker and musical therapy pioneer tells pharmaphorum how his emerging field stands at an important threshold. History provides a wealth of commentary on the emotional value of music. One of the earliest came from Plato, who concluded that “rhythm and harmony find their way into the inward places of the …

Prof Nigel Osborne: Science is catching up with ‘medical music’ Read More »

NICE backs Cosentyx’ use in thousands of children with psoriasis

NICE has recommended broadening NHS use of Novartis’ IL-17 inhibitor Cosentyx to include children aged six to 17 with severe plaque psoriasis. The cost-effectiveness agency says in draft guidance that Cosentyx (secukinumab) should be offered as an option to patients in this age bracket who either don’t respond to or cannot tolerate other systemic treatments. …

NICE backs Cosentyx’ use in thousands of children with psoriasis Read More »

Patient Testimonial | Mr. Paul and Ms. Simona Underwent IVF in Fakih Hospital, Dubai

Introduction: Mr. Paul and Ms. Simona from the USA were childless and wished they had a kid. They never thought that IVF would be part of their story. Their diagnosis report revealed that Ms. Simona would not be able to conceive due to some hormonal issues and IVF was the only way to make their …

Patient Testimonial | Mr. Paul and Ms. Simona Underwent IVF in Fakih Hospital, Dubai Read More »

How to Become a Soy Equol Producer 

Certain gut bacteria can supercharge the benefits of soy foods, resulting in even more bone protection, better control of menopausal symptoms, and lower prostate cancer risk, but how can we foster the growth of these good bacteria?  “Menopause is characterized by a decrease in estrogen, which triggers the uncomfortable symptoms of hot flushes [also known as hot flashes], night …

How to Become a Soy Equol Producer  Read More »

Minister for Seniors at Famed Church Confronts Ageism and the Shame It Brings

Later life is a time of reassessment and reflection. What sense do we make of the lives we have lived? How do we come to terms with illness and death? What do we want to give to others as we grow older? Lynn Casteel Harper, 41, has thought deeply about these and other spiritual questions. …

Minister for Seniors at Famed Church Confronts Ageism and the Shame It Brings Read More »

FDA firms up JAK inhibitor warnings after Xeljanz review

The FDA has concluded its safety review of Pfizer’s JAK inhibitor Xeljanz and Xeljanz XR, requiring revised warnings for the drugs as well as others in the class after finding evidence of elevated risks of serious heart-related events. After looking at the data from Pfizer’s long-term, post-marketing safety study – ORAL Surveillance – the US …

FDA firms up JAK inhibitor warnings after Xeljanz review Read More »

Japan’s Moderna Covid vaccine rollout hit by recall and contamination scares

Foreign materials including stainless steel identified in batches of Covid-19 vaccine though no safety or efficacy issues have been reported The Moderna coronavirus vaccine programme in Japan has been hit by a series of contamination incidents, prompting it to recall 1.63m doses found to contain metal fragments. Other potential contaminants have been identified in separate …

Japan’s Moderna Covid vaccine rollout hit by recall and contamination scares Read More »

NICE backs NHS use of Novartis’ cholesterol drug Leqvio

Novartis’ cholesterol-lowering drug Leqvio will be made available on the NHS in England and Wales, and could help to prevent up to 30,000 deaths, according to NICE. The PCSK9-targeting oligonucleotide – which is already available in Scotland – requires dosing just twice a year and has been approved by the health technology assessment (HTA) agency …

NICE backs NHS use of Novartis’ cholesterol drug Leqvio Read More »

To Quarantine or Not: The Hard Choices Schools Are Leaving to Parents and Staff

On the second day of high school in Texas, Natosha Daniels’ 14-year-old daughter went all day without eating because she did not want to remove her mask. The teen’s school has a couple of thousand students, and the cafeteria was crowded. Plus Round Rock Independent School District outside Austin didn’t require masks, so some students …

To Quarantine or Not: The Hard Choices Schools Are Leaving to Parents and Staff Read More »

Bayer Initiates P-III OASIS Program of Elinzanetant for the Treatment of Vasomotor Symptoms During Menopause

Shots: The company initiates P-III OASIS program to evaluate the efficacy and safety of elinzanetant (120mg, qd) in 1300 patients with vasomotor symptoms during menopause at 200+ centers across 20+ countries The design and dosing of the P-III clinical development program is based on the results from two P-II studies i.e., P-Ib/IIa RELENT-1 & P-IIb …

Bayer Initiates P-III OASIS Program of Elinzanetant for the Treatment of Vasomotor Symptoms During Menopause Read More »

Novartis Signs an Agreement with NHS to Commercialize Leqvio (inclisiran) for the Treatment of Cardiovascular Disease

Shots: The agreement follows the NICE recommendation to deliver Leqvio via a population health management approach for high-risk cardiovascular patients across England The NICE recommendation was based on Novartis’s ORION clinical research program including P- III trials ORION-9/10/11 evaluating the safety, efficacy, and tolerability of inclisiran in 3,600 patients with CVD which showed that the …

Novartis Signs an Agreement with NHS to Commercialize Leqvio (inclisiran) for the Treatment of Cardiovascular Disease Read More »

NFL Rosters and COVID-19 Vaccination Status

Today teams in the National Football League (NFL) made their final roster cuts. In most years, your ability to make the final roster of an NFL team is dependent on one factor: how well can you play football. This year, however, some teams used additional criteria to determine whether a player made the team. ESPN …

NFL Rosters and COVID-19 Vaccination Status Read More »

Quest Candy Bite Waffles

Summer. We think it’s a time for long, lazy days, swimming pools, assorted flights of fancy and, of course, delicious, indulgent, gooey treats. And, wow, do we have you covered in that last department. Look no further than these Questified Candy Bite Waffles for some serious summertime sweet tooth satisfaction. […]

DayTwo Scores $37M to Expand Microbiome-Based Personalized Nutrition Treatment for Diabetes

By JESSICA DaMASSA, WTF HEALTH People with Diabetes can get ready to celebrate: “The ‘Era of Lancets’ is over.” Precision nutrition startup, DayTwo, is scaling up its microbiome-based program, which takes the guesswork (and finger pricks) out of Diabetes management by offering its members food predictions that identify how their bodies will respond to any …

DayTwo Scores $37M to Expand Microbiome-Based Personalized Nutrition Treatment for Diabetes Read More »

How Much Lead Leaches Into Organic Chicken Bone Broth?

“Lead poisoning still occurs in the United States despite extensive prevention efforts and strict regulations.” Ayurvedic supplements specifically marketed to pregnant women, for example, exceeded safety levels by up to 4 million percent, making Ayurvedic medicine use and lead poisoning “a continued concern in the United States.” In fact, “heavy metals are added intentionally to …

How Much Lead Leaches Into Organic Chicken Bone Broth? Read More »

Top 12 Cardiologists in India | MediGence

A cardiologist is a doctor who specializes in the treatment of the cardiovascular system, including the heart and the blood vessels. Cardiologists also promote habits, which helps boost heart health. Cardiologists are qualified to treat heart failure, heart attacks, heart valve disease, arrhythmia, and high blood pressure. Cardiologists work in hospitals and as private practices. …

Top 12 Cardiologists in India | MediGence Read More »

Catalent sees $1B Bettera deal as a key to growth in nutrition and consumer health

Tie-ups of candy makers and nutritional product companies into a single firm called Bettera has culminated in a $1 billion acquisition by Catalent. The global contract manufacturing giant plans to leverage Bettera’s ability to produce gummies and chewables as a way to offer its customers new formulation options for nutraceutical products.

‘My Time to Live’: Through Novel Program, Kidney Patients Get Palliative Care, Dialysis ’Til the End

After a decade of living with chronic kidney disease, Vonita McGee knows her body is wearing out. At 63, McGee undergoes dialysis sessions three times each week at a Northwest Kidney Centers site near her Burien, Washington, home to rid her blood of waste and water. She has endured the placement of more than a …

‘My Time to Live’: Through Novel Program, Kidney Patients Get Palliative Care, Dialysis ’Til the End Read More »

Lemon Thumbprint Cookies using Quest Bars – Recipe

Want to make your mark? How about really make an impression? The truth is that these Lemon Thumbprint Cookies are unique, they really stand out, and everyone will want to get their hands on them. Check out the full recipe below NUTRITIONAL INFO ORANGE CREAM BARS Yields: 9 servings | […]

Blueberry Pineapple Upside Down Cake using Quest Hero Bar

They’re going to flip when you serve them this Blueberry Pineapple Upside Down Cake using Quest Hero Bars & Protein Powder. When they try it, they won’t know which way is up. They’ll be head over heels. They…pardon us. What we mean is that it’s really quite tasty. Check out […]

Strawberry Trifles using Quest Protein Cookies – Recipe

We happen to think this recipe for Strawberry Trifles is very serious. We aren’t kidding. Do yourself a favor and indulge. There’s nothing trifling about 1g of sugar. Check out the full recipe below NUTRITIONAL INFO STRAWBERRY TRIFLES Yields: 3 servings |  Serving Size: 1/3 Trifle Calories: 145  | Protein: […]

Incyte, MorphoSys’ CAR-T rival tafasitamab approved in EU

Incyte and MorphoSys’ antibody therapy tafasitamab has been approved in Europe, promising to provide a more convenient alternative to expensive and cumbersome CAR-T therapies for patients with certain types of lymphoma. The European Commission has approved tafasitamab in combination with Bristol-Myers Squibb’s Revlimid (lenalidomide), followed by the antibody on its own, for the treatment of …

Incyte, MorphoSys’ CAR-T rival tafasitamab approved in EU Read More »

Appeals court reverses $1.2bn judgment against Gilead in BMS CAR-T case

Gilead Sciences’ Kite Pharma has won a key victory on appeal in its long-running dispute with Bristol-Myers Squibb over patents relating to CAR-T therapies, overturning a $1.2 billion fine levied last year. In December 2019, a jury found that Kite infringed on a patent owned by Juno Therapeutics, a division of BMS acquired through its …

Appeals court reverses $1.2bn judgment against Gilead in BMS CAR-T case Read More »

KHN’s ‘What the Health?’: Vaccine Approval Moves the Needle on Covid

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The Food and Drug Administration gave full approval this week to the covid-19 vaccine from Pfizer and BioNTech, which will henceforth be known as “Comirnaty.” It is …

KHN’s ‘What the Health?’: Vaccine Approval Moves the Needle on Covid Read More »

Inside 1-Year-Old Calibrate’s $100M Raise for ‘Rx + Behavior Change’ Weight Loss

By JESSICA DaMASSA, WTF HEALTH Just ONE-year in market, and Calibrate has already closed a $100M Series B co-led by Founders Fund and Tiger Global, with participation from Optum Ventures, Forerunner Ventures, Threshold Ventures, and Redesign Health. Why is this virtual care startup getting so much attention (and funding) from so many notable health tech …

Inside 1-Year-Old Calibrate’s $100M Raise for ‘Rx + Behavior Change’ Weight Loss Read More »

J&J lung cancer initiative will use Optellum’s ‘digital biomarker’ tech

Three years ago, Johnson & Johnson set up a wide-ranging initiative with Boston University to try to improve lung cancer survival rates through prevention and early intervention. Now, its calling on artificial intelligence specialist Optellum to help with that effort. UK-based Optellum has developed an AI-powered clinical decision support – called Virtual Nodule Clinic – …

J&J lung cancer initiative will use Optellum’s ‘digital biomarker’ tech Read More »

Summer Sale – 20% Off Everything

All digital downloads, shirts, and outreach material on DrGreger.org are 20 percent off until tomorrow, August 27! Proceeds go to support NutritionFacts.org. We are thrilled to debut our new diversity shirt! We have long stressed the importance of dietary diversity. Each plant family has a unique combination of phytonutrients, which is one of the reasons I …

Summer Sale – 20% Off Everything Read More »

Digital mental health firms Headspace and Ginger in $3bn merger

A merger between two digital mental health companies – Headspace and Ginger – will create a $3 billion giant in a category that has been growing at breakneck speed as a result of the COVID-19 pandemic. The deal brings together Headspace’s meditation and mindfulness app – used by millions of people around the world – …

Digital mental health firms Headspace and Ginger in $3bn merger Read More »

Mental health unicorns Headspace, Ginger merge into $3B company 

The two companies will merge to form Headspace Health, which will combine Headspace’s many meditation and wellness exercises with Ginger’s coaching and therapy services. The combined company will have more than 800 employees and a $3 billion valuation. 

Trinity Health Mid-Atlantic to deploy NeuroFlow’s mental health tools across 3 hospitals

Through a program funded by Independence Blue Cross Foundation, 1,800 frontline healthcare workers across the three Pennsylvania-based hospitals will gain access to NeuroFlow’s technology, which will measure and track their mental health symptoms and provide support via educational resources and a clinical care team.

Lilly taps Lycia for protein degrader tech in $1.6bn deal

Eli Lilly has bolstered its position the fast-emerging area of protein degrader drugs, agreeing a $1.6 billion-plus deal with Lycia Therapeutics spanning up to five drug targets. The drugmaker has looked close to home for its latest entry into the category, as Lycia’s founder Prof Carolyn Bertozzi has held a seat on its board of …

Lilly taps Lycia for protein degrader tech in $1.6bn deal Read More »

Ginger and Headspace Merge: CEOs Let Us In On What’s Next for Digital Mental Health Super Company

By JESSICA DaMASSA, WTF HEALTH The thinking behind the merger-of-equals between on-demand mental health company, Ginger, and mindfulness and meditation company, Headspace, is revealed in this in-depth chat with Headspace CEO CeCe Morken and Ginger CEO Russell Glass. The combined entity will be known as Headspace Health, with CeCe as its President and Russell as …

Ginger and Headspace Merge: CEOs Let Us In On What’s Next for Digital Mental Health Super Company Read More »

Older people ‘more likely to engage with digital physiotherapy care’

Researchers in the US have found that older people are far more likely to engage with digital physiotherapy programmes digitally than those in younger age groups. Gen Xers, working-age baby boomers and retirees – collectively the over-41 age bracket – were more likely to start a musculoskeletal (MSK) programme delivered via digital channels than Gen …

Older people ‘more likely to engage with digital physiotherapy care’ Read More »

Uncertainty and Vaccination Decisions

An interesting result from Courbage and Peter (2021): …uncertainty about the probability of side effects and the efficacy of the vaccine always reduces take-up under ambiguity aversion. However, uncertainty about the underlying disease, being the probability of sickness or the probability of a severe course of disease, may either encourage or discourage vaccination. Because vaccination …

Uncertainty and Vaccination Decisions Read More »

Vertex builds in gene editing yet again, with $1.2bn Arbor deal

Vertex Pharma has ramped up its involvement in gene-editing medicines for the third time in a matter of months, agreeing a partnership with CRISPR specialist Arbor Biotechnologies that could be worth up to $1.2 billion. The latest deal allows Vertex to tap into Arbor’s technology platform to develop cell therapies for diseases like type 1 …

Vertex builds in gene editing yet again, with $1.2bn Arbor deal Read More »

Novartis’ bid to extend Kymriah into earlier use hits a roadblock

Novartis’ CAR-T therapy Kymriah racked up back-to-back approvals in acute lymphoblastic leukaemia and large B-cell lymphoma a few years ago, but hasn’t added to its label since. Now, a bid to move it onto earlier-stage use in lymphoma has ended in failure. In the phase 3 BELINDA trial, Kymriah (tisagenlecleucel) was unable to extend event-free …

Novartis’ bid to extend Kymriah into earlier use hits a roadblock Read More »

Soy Phytoestrogens for Menopausal Symptoms

Does soy food consumption explain why Japanese women appear to be so protected from hot flash symptoms? When women hit menopause and their ovaries shut down, the estrogen level in their body drops 95 percent. This is good news for the endometrium, the lining of the uterus. Otherwise, the constant estrogen signaling could eventually result in endometrial cancer. In fact, …

Soy Phytoestrogens for Menopausal Symptoms Read More »

IL-17 tailender UCB gets EU OK for bimekizumab in psoriasis

UCB has been bringing up the rear in the IL-17 inhibitor category with bimekizumab, but now has EU approval for the drug and thinks it can mount a stiff challenge to the leaders, including Novartis’ big-selling Cosentyx. The European Commission has cleared the drug as Bimzelx for the treatment of moderate to severe plaque psoriasis …

IL-17 tailender UCB gets EU OK for bimekizumab in psoriasis Read More »

Dosis Expands Dosing Platform to Personalize Anemia Management

What You Should Know: – Dosis, the AI-powered precision dosing platform on a mission to transform healthcare, has announced the release of its Strategic Iron Advisor (SIA) tool, the first precision dosing tool on the market for intravenous iron.  – SIA is a sub-module that works with Dosis’s existing anemia tool, Strategic Anemia Advisor (SAA), …

Dosis Expands Dosing Platform to Personalize Anemia Management Read More »

Pfizer, BioNTech Covid-19 vaccine is awarded full FDA approval

Full FDA approval makes the Pfizer/BioNTech Covid-19 vaccine the first to reach that milestone. But the regulatory decision also flagged a potential risk of heart inflammation, particularly in young males, and the agency has asked the companies to conduct additional clinical research.

COVID prompts another milestone, as India clears first DNA vaccine

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. This is the first DNA vaccine to ever receive regulatory authorisation anywhere in the world, the first COVID-19 jab approved in India to treat children …

COVID prompts another milestone, as India clears first DNA vaccine Read More »

Readers and Tweeters Ponder Vaccines and Points of Fairness

Letters to the Editor is a periodic feature. We welcome all comments and will publish a selection. We edit for length and clarity and require full names. Higher Insurance Rates for the Unvaccinated? Snuff Out That Idea This is about Dr. Elisabeth Rosenthal’s comments on “All In With Chris Hayes” (“Analysis: Don’t Want a Vaccine? Be Prepared to …

Readers and Tweeters Ponder Vaccines and Points of Fairness Read More »

BeiGene Reports NMPA’s Acceptance of sBLA for Tislelizumab (BGB-A317) to Treat Nasopharyngeal Cancer in China

Shots: The sBLA is based on P-III RATIONALE 309 trial evaluating the efficacy & safety of tislelizumab + CT vs PBO + CT in a ratio (1:1) in 263 Asian patients with recurrent or metastatic NPC The 1EPs of a trial is PFS as assessed by IRC in ITT population & 2EPs includes OS, ORR, …

BeiGene Reports NMPA’s Acceptance of sBLA for Tislelizumab (BGB-A317) to Treat Nasopharyngeal Cancer in China Read More »

FDA issues warning on robot-assisted breast cancer surgery

The FDA has issued a safety alert about the use of robot-assisted surgical (RAS) devices for use in mastectomy procedures, pointing out that their safety and efficacy have not been established. The move comes amid reports that some people are being offered RAS for the prevention or treatment of breast cancer, sometimes as part of …

FDA issues warning on robot-assisted breast cancer surgery Read More »

AstraZeneca drug succeeds in Covid-19 prevention; regulatory filings on the way

An AstraZeneca antibody drug for Covid-19 has clinical data showing the drug reduced the risk of infection by 77%. With the results, the pharmaceutical giant pulls ahead of other companies developing injectable versions of antibody drugs for Covid-19 prevention.

AstraZeneca drug acquired in Alexion acquisition falls short in pivotal ALS trial

Alexion Pharmaceuticals drug Ultomiris is already approved to treat a rare blood disorder, but the company hoped the antibody’s approach could also work in amyotrophic lateral sclerosis. Despite failing in ALS, Alexion, recently acquired by AstraZeneca, brings additional clinical-stage programs for rare diseases.

School or ‘Russian Roulette’? Amid Delta Variant and Lax Mask Rules, Some Parents See No Difference

The child had just started kindergarten. Or, as her mother called it, “Russian roulette.” That’s because her school district in Grand Junction, Colorado, experienced one of the nation’s first delta-variant outbreaks last spring, and now school officials have loosened the rules meant to protect against covid-19. The mother, Venessa, who asked not to be named …

School or ‘Russian Roulette’? Amid Delta Variant and Lax Mask Rules, Some Parents See No Difference Read More »

After Pandemic Ravaged Nursing Homes, New State Laws Protect Residents

When the coronavirus hit Martha Leland’s Connecticut nursing home last year, she and dozens of other residents contracted the disease while the facility was on lockdown. Twenty-eight residents died, including her roommate. “The impact of not having friends and family come in and see us for a year was totally devastating,” she said. “And then, …

After Pandemic Ravaged Nursing Homes, New State Laws Protect Residents Read More »

Biden’s No-Jab-No-Job Order Creates Quandary for Nursing Homes

President Joe Biden’s edict that nursing homes must ensure their workers are vaccinated against covid-19 presents a challenge for an industry struggling to entice its lowest-paid workers to get shots without driving them to seek employment elsewhere. Although 83% of residents in the average nursing facility are vaccinated, only 61% of a home’s workers are …

Biden’s No-Jab-No-Job Order Creates Quandary for Nursing Homes Read More »

Astellas and FibroGen’s Evrenzo (roxadustat) Receive EC’s Approval for Symptomatic Anemia Associated with Chronic Kidney Disease

Shots: The approval is based on the P-III program including 8 studies evaluating Evrenzo in 9600 patients with symptomatic anemia associated with CKD, regardless of dialysis status & prior ESA treatment. Following the EC’s approval, FibroGen to receive $120M milestones along with royalties based upon EU sales The results demonstrated that the therapy was effective …

Astellas and FibroGen’s Evrenzo (roxadustat) Receive EC’s Approval for Symptomatic Anemia Associated with Chronic Kidney Disease Read More »

KHN’s ‘What the Health?’: Booster Time

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. As covid-19 cases in the U.S. continue to rise, the Biden administration is countering with new strategies. The latest efforts include preparing for vaccine boosters starting this …

KHN’s ‘What the Health?’: Booster Time Read More »

What Should We Do to Lower Lead Levels in Breast Milk?

What are the effects of sodium and calcium intake on blood lead levels in pregnant and breastfeeding women?  Although our skeleton “has predominantly been considered a storage site for sequestering absorbed lead, bone is not simply an inert storage site. Once deposited in bone, lead can be remobilized from bone” back into the bloodstream if, for example, we …

What Should We Do to Lower Lead Levels in Breast Milk? Read More »

Sentara Healthcare Taps Sensyne to Deploy Clinical Algorithms for CKD & CHF

What You Should Know: – Sentara Healthcare, a health system in NC and VA, just partnered with Sensyne Health to drive clinical research with ethical AI. – As part of a collaboration agreement, Sentara also becomes the first of several U.S. health systems that will partner with Sensyne to implement new clinical algorithms to support …

Sentara Healthcare Taps Sensyne to Deploy Clinical Algorithms for CKD & CHF Read More »

8 Healthiest Beans for Legume Lovers

Love legumes? Bookmark this list of the healthiest beans! Beans and their legume cousins are largely unsung nutritional heroes. “Beans have so many nutritional benefits,” says Krista Maguire, R.D., C.S.S.D., nutrition manager at Beachbody. “They contain fiber and plant-based protein, which can help keep you feeling full and satisfied,” she explains. “In addition, they are rich in …

8 Healthiest Beans for Legume Lovers Read More »

How to Cook Broccoli 5 Different (and Delicious!) Ways

To squeeze more greens into your meals, look no further than the humble broccoli. Broccoli provides fiber and vitamin C — “basically a lot of the good stuff most people don’t get enough of,” says Brittany Crump, M.P.H., R.D. at Savor Nutrition. This versatile veggie can be used to make creative recipes like broccoli tots, broccoli gratin, or egg …

How to Cook Broccoli 5 Different (and Delicious!) Ways Read More »

Why Blood Lead Levels Rise at Pregnancy and Menopause  

The lead trapped in our skeleton can leach back into our bloodstream when we temporarily or permanently lose bone due to pregnancy, weight loss, menopause, or osteoporosis.  The half-life of lead in the bloodstream is only about a month. In other words, if you feed people lead for about a hundred days to boost up their blood levels and then you stop giving …

Why Blood Lead Levels Rise at Pregnancy and Menopause   Read More »

Novartis’ Cosentyx (secukinumab) Receives the NMPA’s Approval for the Treatment of Pediatric Psoriasis in China

Shots: The approval is based on two P-III international studies that evaluate cosentyx in pediatric patients aged 6 to <18 yrs. with mod. to sev. PsO who are candidates for systemic therapy or phototherapy The results showed that the therapy is safe and effective for children and adults with PsO. Additionally, therapy has supported the …

Novartis’ Cosentyx (secukinumab) Receives the NMPA’s Approval for the Treatment of Pediatric Psoriasis in China Read More »

Ultromics Raises $33M for AI-Enabled Echocardiograms to Help Clinicians Diagnose Heart Disease

What You Should Know: – Today, Ultromics, an Oxford, England-based health-tech startup announced it has raised $33M in Series B funding led by Blue Ventures, the investing arm of Blue Cross Blue Shield, and also includes investment from Optum Ventures, GV, and Oxford Sciences. –  Born at the University of Oxford and built-in partnership with …

Ultromics Raises $33M for AI-Enabled Echocardiograms to Help Clinicians Diagnose Heart Disease Read More »

Shaping the future of ovarian cancer diagnosis with femtech

Israeli femtech start-up GinaLife is developing a platform of biomarker strategies supported by artificial intelligence and data science for the early detection of problems in women’s health. CEO and co-founder Inbal Zafir-Lavie tells pharmaphorum more. Six years ago, research scientist Inbal Zafir-Lavie tragically lost her 38-year-old sister Hava Zafir to colorectal cancer. Due to her …

Shaping the future of ovarian cancer diagnosis with femtech Read More »

Make the Best Homemade Veggie Burger in 7 Easy Steps

Burgers every day of the week? Yes, please. If you want to enjoy a veggie burger every night of the week, Dana Ellis Hunnes Ph.D., MPH, R.D., author of the book Recipe For Survival, says go for it — as long as its “full of beans, fresh vegetables, and other healthy whole grains or leafy greens.” (Don’t worry, …

Make the Best Homemade Veggie Burger in 7 Easy Steps Read More »

KHN’s ‘What the Health?’: The Senate Acts

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The Senate has set the stage for a busy fall that will include debate on a broad array of health issues, such as prescription drug prices, Medicare …

KHN’s ‘What the Health?’: The Senate Acts Read More »

Second FDA clinical hold for Aprea cancer drug cites safety data in another study

For the second time in a week, the FDA placed a clinical hold on an Aprea Therapeutics cancer drug. The biotech said the agency cited safety and efficacy data from a prior failed clinical trial that tested the small molecule in a different form of cancer.

Mahana raises $61m for digital therapeutic for IBS

Mahana Therapeutics has raised second-round financing of $61 million that will be used to launch what it says will be the first prescription digital therapeutics (DTx) for irritable bowel syndrome, one of several digital health products in its pipeline. The Mahana IBS tool – a three-month course that uses cognitive behavioural therapy (CBT) to log …

Mahana raises $61m for digital therapeutic for IBS Read More »

The Dangers of Talcum Powder

What role does diet and baby powder play in the development of fibroids and ovarian cancer?  If you randomly select a group of women and ultrasound their uterus, most of them have fibroid tumors by age 50—and by most, I mean more than 80 percent of black women and nearly 70 percent of white women. As you can see at 0:23 in my video Talcum …

The Dangers of Talcum Powder Read More »

NICE changes stance on Lilly’s breast cancer dug Verzenio

After rejecting Eli Lilly’s Verzenio for breast cancer therapy earlier this year, NICE has relented, recommending the drug for routine NHS use alongside hormonal therapy fulvestrant. A final appraisal document from the health technology assessment (HTA) agency backs the use of Verzenio (abemaciclib) alongside fulvestrant for the treatment of women with hormone receptor-positive, HER2-negative breast …

NICE changes stance on Lilly’s breast cancer dug Verzenio Read More »

Breast cancer drug approved for NHS after maker agrees discount

Reversal of earlier rejection by Nice of abemaciclib – known as Verzenios – is welcomed by campaigners A breast cancer drug that was rejected for routine NHS use in England earlier this year has now been recommended by health officials after a discount was agreed with the manufacturer. The decision has been described as “fantastic …

Breast cancer drug approved for NHS after maker agrees discount Read More »

Find Out How to Cook Magically Delicious Mushrooms

If you want to make a meal magical, learn how to cook mushrooms. Mushrooms add nutrition and tons of flavor — if you know how to properly cook them. “Mushrooms are low in calories and pack a nutrition punch,” says registered dietitian nutritionist Vandana Sheth, R.D.N., CDCES, FAND, author of My Indian Table: Quick & Tasty Vegetarian Recipes. …

Find Out How to Cook Magically Delicious Mushrooms Read More »

Why Doesn’t Medicare Cover Services So Many Seniors Need?

Sorry, Joe Namath. Despite what you keep saying in those TV ads, under Medicare, seniors are not “entitled to eliminate copays and get dental care, dentures, eyeglasses, prescription drug coverage, in-home aides, unlimited transportation and home-delivered meals, all at no additional cost.” But if Democratic lawmakers in Congress have their say, seniors could soon be …

Why Doesn’t Medicare Cover Services So Many Seniors Need? Read More »

GW’s Epidyolex (cannabidiol) Receives MHRA’s Approval for the Treatment of Seizures Associated with Tuberous Sclerosis Complex in UK

Shots: The approval is based on P-III safety & efficacy study that evaluates Epidyolex (25 mg/kg/day) vs PBO in patients aged ≥2yrs. as an adjunctive treatment with seizures associated with TSC The study met its 1EPs i.e., reduction in seizure frequency (49% vs 27%). The 2EPs had supported the effects on 1EPs & safety profile …

GW’s Epidyolex (cannabidiol) Receives MHRA’s Approval for the Treatment of Seizures Associated with Tuberous Sclerosis Complex in UK Read More »

Everything You Need to Know About Plant-Based Eggs

Versatile and protein-rich, eggs are a breakfast staple and a key ingredient in baking. But if you follow a vegan diet, have an egg allergy, or you’re looking to reduce your cholesterol intake, you may be considering making the switch to plant-based eggs. As plant-based diets gain popularity, more and more vegan egg alternatives are making it …

Everything You Need to Know About Plant-Based Eggs Read More »

What Is the Science on Cannabis?

What did the National Academies of Sciences’ 468-page report conclude about cannabis?  When some misinformed people hear of the grand opening of a new plant-based medical practice, one plant in particular may come to mind. I’ve gotten a lot of questions about cannabis over the years, and I figure it’s high time to try to clear the …

What Is the Science on Cannabis? Read More »

Cambridge team says AI could diagnose dementia with one scan

Researchers at Cambridge University in the UK are trialling an artificial intelligence system that they think could spot the signs of dementia after a single brain scan. The team – led by Prof Zoe Kourtzi of the university and Alan Turing Institute – told the BBC that the AI could make it possible to start …

Cambridge team says AI could diagnose dementia with one scan Read More »

HER2 heats up as Seagen licenses RemeGen ADC for $2.6bn

Seagen is a specialist in antibody-drug conjugates, but has looked to Chinese biotech RemeGen for a HER2-targeting candidate that could challenge rival drugs from AstraZeneca/Daiichi Sankyo and Roche. The US company is paying $200 million upfront for rex-Asian rights to RemeGen’s disitamab vedotin, with another $2.4 billion in possible future payments tied to future successes …

HER2 heats up as Seagen licenses RemeGen ADC for $2.6bn Read More »

Armed with ph3 trial, Roche preps filing for Polivy in first-line DLBCL

Roche has the results it was hoping for in a phase 3 trial of Polivy in newly diagnosed diffuse large B-cell lymphoma (DLBCL) – an indication it thinks could be worth up to $2 billion. The Swiss drugmaker reported top-line results from the POLARIX study this morning, showing that Polivy (polatuzumab vedotin) was able to …

Armed with ph3 trial, Roche preps filing for Polivy in first-line DLBCL Read More »

Some Are Chasing Extra Vaccine Shots, While Scientists Debate

Boosters may not be necessary yet, many experts say, and the pursuit of additional shots raises ethical questions.

Insurers back kidney care startup Cricket in $83.5M round

Cigna Ventures and Blue Shield of California contributed to a funding round for Cricket Health, a startup that provides services to help patients identify chronic kidney disease and get support in treatment. The investment was led by Valtruis, a firm that invests in value-based care companies.

Cricket Health Secures $83.5M to Expand Value-Based Kidney Care Model to Health Plans

What You Should Know: – Cricket Health, a San Francisco, CA-based provider of value-based kidney care with a clinically-proven approach to managing chronic kidney disease (CKD) and end-stage kidney disease (ESKD), today announced it has raised $83.5 million in Series B funding round led by Valtruis with a strategic investment from Blue Shield of California. …

Cricket Health Secures $83.5M to Expand Value-Based Kidney Care Model to Health Plans Read More »

The Effect of Avocados on Small, Dense, LDL Cholesterol

What are the effects of oatmeal, walnuts, extra virgin olive oil, and avocados on LDL cholesterol size?  When a headline reads “Avocados could improve your cholesterol—and more,” the article and others like it are largely talking about substitution experiments, where avocado is added to the diet as a replacement for animal fats. In that case, it’s no wonder cholesterol goes down. Dairy and poultry are the two greatest contributors of cholesterol-raising saturated fat …

The Effect of Avocados on Small, Dense, LDL Cholesterol Read More »

Bayer bolsters R&D platform with $2bn Vividion takeover

Bayer headlined its second-quarter results this morning by unveiling a deal to buy Vividion Therapeutics, saying it will boost its ability to develop medicines against targets once considered “undruggable.” Bayer is paying $1.5 billion upfront to claim ownership of Vividion‘s drug discovery platform, which uses chemoproteomics to identify new binding sites on proteins and find …

Bayer bolsters R&D platform with $2bn Vividion takeover Read More »

“Sabiduría y miedo” llevan al 90% de los adultos mayores de EE.UU. a vacunarse contra covid

En medio del último aumento de casos de covid-19 y hospitalizaciones, Estados Unidos alcanzó el martes 3 de agosto un hito que algunos pensaban que era inalcanzable: el 90% de las personas de 65 años o más están al menos parcialmente vacunadas contra la enfermedad. Esto es más de 49 millones de adultos mayores vacunados. …

“Sabiduría y miedo” llevan al 90% de los adultos mayores de EE.UU. a vacunarse contra covid Read More »

Failed trial nixes another FDA approval, this time for BMS’ Istodax

Bristol-Myers Squibb’s HDAC inhibitor Istodax has been on the US market for a decade as a treatment for peripheral T-cell lymphoma (PTCL), but will now be withdrawn from sale after a failed phase 3 trial. Istodax (romidepsin) – originally developed by Celgene – is the latest in a string of cancer drugs originally given accelerated …

Failed trial nixes another FDA approval, this time for BMS’ Istodax Read More »

‘Wisdom and Fear’ Lead 90% of U.S. Seniors to Covid Vaccines

Amid the latest surge in covid-19 cases and hospitalizations, the United States on Tuesday hit a milestone that some thought was unattainable: 90% of people 65 and older are at least partly vaccinated against the disease. That’s more than 49 million seniors vaccinated. Overall, 70% of adults have been inoculated, at least partly, and nearly …

‘Wisdom and Fear’ Lead 90% of U.S. Seniors to Covid Vaccines Read More »

Boost vaccination rates with frictionless self-scheduling

It’s time to accelerate the pace of COVID-19 vaccinations. Healthcare experts are increasingly concerned about the rapid spread of the highly contagious delta variant, which now makes up over 83% of COVID-19 cases. This variant is estimated to be 60% more transmissible than previous strains, and while vaccination doesn’t eliminate the risk, it does reduce …

Boost vaccination rates with frictionless self-scheduling Read More »

Boost vaccination rates with frictionless self-scheduling

As the country strives to ramp up the pace of COVID-19 vaccinations, providers need to take new approaches to drive registration volume. Healthcare experts are increasingly concerned about the rapid spread of the highly contagious delta variant, which now makes up over 83% of COVID-19 cases. This variant is estimated to be 60% more transmissible …

Boost vaccination rates with frictionless self-scheduling Read More »

Covid drug could help reduce heavy menstrual bleeding

Trial suggests anti-inflammatory dexamethasone may offer welcome alternative to intra-uterine system Researchers hope a steroid that shot to prominence during the Covid pandemic may help reduce blood loss in those who experience heavy periods. The cheap anti-inflammatory dexamethasone was discovered to improve survival rates among patients critically ill with Covid. It is also used for …

Covid drug could help reduce heavy menstrual bleeding Read More »

What Do Avocados Do to Your Cholesterol?

Can guacamole lower your cholesterol as well as other whole–food fat sources like nuts, or is that just spin by the avocado industry?  “Avocados are the richest known fruit source of phytosterols,” the cholesterol-lowering nutrients found in plant foods, brags a review sponsored by the HASS Avocado Board. The operative word, though, is fruit.  Yes, avocados contain more phytosterols compared to other fruit, but phytosterols are fat-soluble …

What Do Avocados Do to Your Cholesterol? Read More »

Germany confirms booster COVID jabs will start in September

Germany’s health ministry has said it will start offering booster COVID-19 vaccines to vulnerable people from next month, amid concerns about rising cases of the delta variant of the coronavirus. Health Minster Jens Spahn said the decision was also taken because of concerns that the immune response stimulated by COVID-19 vaccines may start to diminish …

Germany confirms booster COVID jabs will start in September Read More »

UCB’s bimekizumab ‘pre-approved’ using NICE fast-track scheme

UCB’s bimekizumab hasn’t been approved for marketing in Europe yet, but has already been given the nod for NHS use in England and Wales under a new fast-track scheme introduced by NICE. The IL-17 inhibitor is the first to go through a new process aimed at accelerating appraisals for drugs deemed to be low-risk, which …

UCB’s bimekizumab ‘pre-approved’ using NICE fast-track scheme Read More »

Olympic BMX funding cut wins gold for sexism | Brief letters

Drug companies | Political parties | UK Sport | Happy news | Mixed-up names Instead of fining drug firms that hike their prices (Report, 29 July) a more effective deterrent might be to strip them of their patent at the first sign of overpricing. I’m not sure even large fines will make any difference to …

Olympic BMX funding cut wins gold for sexism | Brief letters Read More »

Once Common, COVID-19 Deaths in Long-Term-Care Were Rare across Most States in June

Early in the COVID-19 pandemic, residents and staff at nursing homes and other long-term care facilities accounted for a huge share of COVID deaths, but a new KFF analysis finds that they were relatively rare events across the country in June. The analysis finds that 13 states and the District of Columbia in June reported…More

COVID-19 Cases and Deaths in Long-Term Care Facilities through June 2021

This data note examines state-level data on COVID-19 cases and deaths in long-term care facilities through June prior to the recent rise in cases and deaths nationally linked to the spread of the Delta variant. It finds long-term care deaths down 96% from their peak in December as the nation’s vaccination effort began.

Restoring a Sense of Belonging: The Unsung Importance of Casual Relationships for Older Adults

In May, Vincent Keenan traveled from Chicago to Charlottesville, Virginia, for a wedding — his first trip out of town since the start of the pandemic. “Hi there!” he called out to customers at a gas station where he’d stopped on his way to the airport. “How’s your day going?” he said he asked the …

Restoring a Sense of Belonging: The Unsung Importance of Casual Relationships for Older Adults Read More »

12,000 Square Miles Without Obstetrics? It’s a Possibility in West Texas

The message from Big Bend Regional Medical Center was stark: The only hospital in a sparsely populated region of far West Texas notified local physicians last month that because of a nursing shortage its labor and delivery unit needed to temporarily close its doors and that women in labor should instead be sent to the …

12,000 Square Miles Without Obstetrics? It’s a Possibility in West Texas Read More »

Biofourmis Earns FDA Breakthrough Device Designation for Digital Therapeutic for Heart Failure

What You Should Know: – Biofourmis, a Boston-based global leader in virtual care and digital therapeutics, announced its BiovitalsHF® solution is the first-ever heart failure digital therapeutic to receive a Breakthrough Device designation from the U.S. Food and Drug Administration (FDA). – The Breakthrough Devices Program was created to provide patients and providers with timely …

Biofourmis Earns FDA Breakthrough Device Designation for Digital Therapeutic for Heart Failure Read More »

NIH digital tool aims to boost enrolment into Alzheimer’s studies

With a string of new drugs for Alzheimer’s disease making their way through late-stage clinical testing, the demand for suitable subjects to enrol into trials is running at an all-time high – and threatens to outstrip supply. Now, the National Institute on Aging (NIA) – part of the US National Institutes of Health (NIH) – …

NIH digital tool aims to boost enrolment into Alzheimer’s studies Read More »

Novel Therapies form the Nucleus of the Growth in the Crohn’s Disease Therapeutic Market

Crohn’s disease is one of the most prevalent types of Inflammatory bowel diseases characterized by abdominal pain and diarrhea, with patients often experiencing weight loss and perianal disease. Based on the location of the body, Crohn’s disease affects the disease can be of different types, including ileocolitis, ileitis, gastroduodenal Crohn’s disease, jejunoileitis, and Crohn’s colitis. …

Novel Therapies form the Nucleus of the Growth in the Crohn’s Disease Therapeutic Market Read More »

Amid Covid Booster Debate, West Virginia to Check Immunity of Vaccinated Nursing Home Residents

West Virginia raced ahead of the country last winter to get people in nursing homes vaccinated against covid-19, but with cases and hospitalizations on the rise again, state officials want to know whether immunity levels are falling for residents who had their shots. Starting in August, the state plans to begin measuring the levels of …

Amid Covid Booster Debate, West Virginia to Check Immunity of Vaccinated Nursing Home Residents Read More »

Texas law eases prior auth burdens, but payers see it as a dangerous move

The law, which will take effect in September, prohibits payers from requiring pre-approval from certain providers. While providers believe the law will cut administrative burdens, and improve care delivery, payers say it could lead to patient harm.

Some Are Chasing Extra Vaccine Shots, While Scientists Debate

Boosters may not be necessary yet, many experts say, and the pursuit of additional shots raises ethical questions.

Dr. Greger’s Daily Dozen Healthiest of Healthy Foods 

In my book How Not to Die, I center my recommendations around a Daily Dozen checklist of everything I try to fit into my daily routine.  In my book How Not to Die, I suggest we try to center our diets around whole plant foods. Some plants are healthier than others, though. Apparently, you can live for extended periods eating practically nothing but white potatoes, for example, …

Dr. Greger’s Daily Dozen Healthiest of Healthy Foods  Read More »

Pfizer Court Fight Could Legalize Medicare Copays and Unleash ‘Gold Rush’ in Sales

Three years ago, pharma giant Pfizer paid $24 million to settle federal allegations that it was paying kickbacks and inflating sales by reimbursing Medicare patients for out-of-pocket medication costs. By making prohibitively expensive medicine essentially free for patients, the company induced them to use Pfizer drugs even as the price of one of those medicines, …

Pfizer Court Fight Could Legalize Medicare Copays and Unleash ‘Gold Rush’ in Sales Read More »

Technology and empathy help make remote working a success for Elsevier

We at Elsevier were pleased to be one of five companies recognized for their ability to keep remote workers rooted in company culture in this recent Comparably article. Like many organizations during the pandemic, we had to quickly adapt to remote working on a large scale for our international workforce. As the article notes, “Elsevier …

Technology and empathy help make remote working a success for Elsevier Read More »

Medicare vaccine coverage (including how the COVID-19 vaccines are covered)

How does Medicare cover vaccines? Are the paid for by Medicare Part B or Part D? MedPAC’s June 2021 report provides a nice overview. Medicare covers vaccines under Part B and Part D. Part B covers vaccines for influenza, pneumococcal disease, hepatitis B (for patients at high or intermediate risk), and coronavirus disease 2019 (COVID-19), …

Medicare vaccine coverage (including how the COVID-19 vaccines are covered) Read More »

Lacking Dental Coverage, Many People on Medicare Forgo Dental Care, Especially Beneficiaries of Color

Many people enrolled in Medicare go without dental care, especially beneficiaries of color, according to a new KFF analysis of dental coverage and costs for people with Medicare. Almost half of all Medicare beneficiaries (47%) did not have a dental visit within the past year as of 2018, the analysis finds, with rates higher among…More

Medicare and Dental Coverage: A Closer Look

Medicare does not cover routine dental care and about half of Medicare beneficiaries do not have dental coverage. Some beneficiaries have dental coverage through other sources, including Medicare Advantage, but 47% of all beneficiaries have not been to the dentist in the past year and many older adults face high out-of-pocket costs for needed dental …

Medicare and Dental Coverage: A Closer Look Read More »

Psoriasis and Depression: The Lesser-Known Impact of the Disease

By Nolan Brown, Marketing Intern, Butler University VMS BioMarketing Psoriasis is a chronic inflammatory disease of the skin that affects both the personal and social lives of the people it strikes. Psoriasis Awareness Month is an important time to discuss one of the lesser-known impacts of the disease. “Many people are familiar with the physical …

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The Dangers of Oil Pulling 

In my previous articles on oil pulling, I discussed how the ancient practice may be no more effective than swishing with plain water for plaque and gingivitis, doesn’t whiten your teeth, and may even worsen dental erosion. What about oil pulling to treat tooth sensitivity? About a quarter of people have sensitive teeth, for example, …

The Dangers of Oil Pulling  Read More »

Adagio Collaborates with Biocon to Provide COVID-19 Ab Treatment to Patients in India and Other Emerging Markets

Shots: The companies collaborated for Adagio’s ADG20 for both the treatment & prevention of COVID-19 as monothx. or combination regimen Biocon will gain rights to manufacture & commercialize ADG20 for COVID-19 in India and select emerging markets based on the commercial process developed for ADG20. The company will have the access to Adagio’s ongoing P-II/III …

Adagio Collaborates with Biocon to Provide COVID-19 Ab Treatment to Patients in India and Other Emerging Markets Read More »

7 Mango Recipes if You’re Mad About This Gorgeous Fruit

Nothing screams “summer” like delicious mango recipes! The fruit packs a bright, rich flavor, and the color of its flesh even looks like the sun. But if you’re only enjoying this fruit on its own, you’re missing out on all the mango has to offer. “Mango is a sweet fruit, but surprisingly versatile,” says Lindsey Janeiro, …

7 Mango Recipes if You’re Mad About This Gorgeous Fruit Read More »

Catalent Plans Multi-Phase, $100 Million Expansion of Italian Facility to Increase Biologics Manufacturing Capabilities in Europe

SOMERSET, N.J. — Catalent, the leading global provider of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, cell and gene therapies, and consumer health products, today announced that it will commence the first phase of a planned $100 million expansion program at its facility in Anagni, Italy, to add biologics drug substance manufacturing capabilities, supporting the growing European market …

Catalent Plans Multi-Phase, $100 Million Expansion of Italian Facility to Increase Biologics Manufacturing Capabilities in Europe Read More »

Happify rolls out digital therapeutic for anxiety, depression under temporary FDA guidance

Happify is making its app-based treatment available to patients thanks to a loosened FDA guidance last year that lets digital health companies targeting some behavioral health conditions release their product without clearance. The company is launching an investigational study to get data for a future FDA submission.

Facing Headwinds on New Alzheimer’s Drug, Biogen Launches Controversial Campaign

Do you sometimes lose your train of thought or feel a bit more anxious than is typical for you? Those are two of the six questions in a quiz on a website co-sponsored by the makers of Aduhelm, a controversial new Alzheimer’s drug. But even when all responses to the frequency of those experiences are …

Facing Headwinds on New Alzheimer’s Drug, Biogen Launches Controversial Campaign Read More »

Pfizer commits $1B to Arvinas for share of protein degrading breast cancer drug

Arvinas’ early clinical data for its targeted protein degradation drug for breast cancer drew partnering interest from several companies. Pfizer beat them all with a deal that pays the biotech $1 billion to share in the development and commercialization of this therapy.

8 Delicious (and Healthier!) Mayo Substitutes

The creamy texture and tangy flavor of mayonnaise is a staple in so many classic recipes — think potato salad, egg salad, pasta salad, sandwiches, burgers, and dips. But it’s not exactly the pinnacle of healthy condiments, so you may be wondering if a worthy mayo substitute exists. “Classic mayonnaise is made from emulsifying egg …

8 Delicious (and Healthier!) Mayo Substitutes Read More »

Happify launches Ensemble DTx for depression, anxiety in US

Happify Health has launched a prescription digital therapeutic (DTx) – called Ensemble – that can assist the treatment of people with both major depressive disorder and generalised anxiety disorder in the US market. The 10-week smartphone or PC based programme is the first and only prescription DTx for both indications, which according to the digital …

Happify launches Ensemble DTx for depression, anxiety in US Read More »

Pfizer puts up $1bn to buy into Arvinas breast cancer programme

Pfizer has pledged a whopping $11 billion upfront for rights to an Arvinas drug for breast cancer from its protein degrader platform, which harnesses cells’ natural protein-denaturing machinery to remove rogue proteins associated with disease. The deal focuses on ARV-471, currently in phase 2 testing for advanced breast cancer patients whose tumours expresses oestrogen receptors …

Pfizer puts up $1bn to buy into Arvinas breast cancer programme Read More »

A Chilling Cure: Facing Killer Heat, ERs Use Body Bags to Save Lives

As a deadly heat wave scorched the Pacific Northwest last month, overwhelming hospital emergency rooms in a region unaccustomed to triple-digit temperatures, doctors resorted to a grim but practical tool to save lives: human body bags filled with ice and water. Officials at hospitals in Seattle and Renton, Washington, said that as more people arrived …

A Chilling Cure: Facing Killer Heat, ERs Use Body Bags to Save Lives Read More »

How Much Salt Is Too Much?

It’s too simplistic to think of sodium as “bad.” Yes, you should watch your daily salt intake, but that doesn’t mean all sodium in your diet should get the boot. “Sodium is an essential mineral in your body to help maintain fluid balance, muscle contraction, nerve conduction, and more,” explains Chelsey Amer, M.S., R.D.N., owner of Chelsey …

How Much Salt Is Too Much? Read More »

Leading Autoimmune Diseases to Undergo Robust Improvement in Treatment by Major Pharma Companies

As per the American Autoimmune Related Diseases Association (AARDA), nearly 50 million people in the USA are affected by autoimmune diseases such as rheumatoid arthritis, psoriasis, and lupus. These diseases are the second leading cause of chronic illness in the United States. The prevalence is rising at a significant pace at par with heart disease …

Leading Autoimmune Diseases to Undergo Robust Improvement in Treatment by Major Pharma Companies Read More »

Novartis eyes New Year verdict from FDA on delayed Leqvio

Novartis has revealed that the FDA has accepted its resubmission for cholesterol-lowering drug Leqvio – rejected unexpectedly by the US regulator last year – and has set a new action date of 1 January 2022. The drugmaker refiled its application for Leqvio (inclisiran) earlier this month, trying to get the programme back on track in …

Novartis eyes New Year verdict from FDA on delayed Leqvio Read More »

Though Millions Are at Risk for Diabetes, Medicare Struggles to Expand Prevention Program

Damon Diessner tried for years to slim down from his weight of more than 400 pounds, partly because his size embarrassed his wife but even more because his doctors told him he was at risk of developing Type 2 diabetes. His hemoglobin A1c level, a blood sugar marker, was 6.3%, just below the diabetes range …

Though Millions Are at Risk for Diabetes, Medicare Struggles to Expand Prevention Program Read More »

Ginger for Teens Puts “Full-family Approach” to Mental Health Care in Hands of Employers

By JESSICA DaMASSA, WTF HEALTH Digital mental health unicorn Ginger has just launched ‘Ginger for Teens’ in an effort to help the 1-in-5 teens currently suffering from mental health disorders, amid what’s being called a “teen mental health crisis.” No doubt parents are at their wit’s end searching for care, and Ginger is hoping that …

Ginger for Teens Puts “Full-family Approach” to Mental Health Care in Hands of Employers Read More »

Oil Pulling May Worsen Dental Erosion

A review of the effects of oil pulling concluded that, indeed, the ancient practice “may have beneficial effects on oro dental hygiene,” or oral and dental health. I’ve talked before about studies investigating oil pulling and dental health, but what about oral health? That’s the subject of my video Oil Pulling for Teeth Whitening and …

Oil Pulling May Worsen Dental Erosion Read More »

Sen. Wyden: $3.5T Budget May Have to Trim but It Can Set a Path to ‘Ambitious Goals’

Exactly what American health care will look like if Democrats can pass their $3.5 trillion spending plan is unclear, but the senator negotiating its health-related provisions hopes what emerges will be dramatic: the first complete health care system for older Americans and significantly reduced costs for everyone else. “We are setting very, very ambitious goals,” …

Sen. Wyden: $3.5T Budget May Have to Trim but It Can Set a Path to ‘Ambitious Goals’ Read More »

Cytokinetics stock soars on heart drug data that sets stage for Phase 3 studies

A Cytokinetics drug in development for treating a rare heart disorder has promising Phase 2 data suggesting it could compete against a Bristol Myers Squibb drug currently under FDA review. Cytokinetics plans to advance its small molecule to Phase 3 testing by the end of this year.

AstraZeneca bags Imfinzi okay in big Chinese lung cancer market

China has approved AstraZeneca’s PD-1/PD-L1 inhibitor Imfinzi to treat small-cell lung cancer (SCLC), an aggressive form of the disease that accounts for around 15% of all lung cancer cases. The green light from the National Medical Products Administration (NMPA) covers the use of Imfinzi (durvalumab) alongside platinum-based chemotherapy in previously untreated patients with extensive-stage SCLC. …

AstraZeneca bags Imfinzi okay in big Chinese lung cancer market Read More »

The key to psoriasis innovation? Dispelling the shadow of the JAK inhibitor

During the last two decades, the landscape for psoriasis treatment has exploded. The advent of biologic therapies at the turn of the millennium and the subsequent development of T-cell targeted therapies and tumor necrosis factor (TNF) inhibitors have given patients therapeutic options beyond traditional treatments such as topical steroids, tar preparations, oral systemics, and light …

The key to psoriasis innovation? Dispelling the shadow of the JAK inhibitor Read More »

The key to psoriasis innovation? Dispelling the shadow of the JAK inhibitor

During the last two decades, the landscape for psoriasis treatment has exploded. The advent of biologic therapies at the turn of the millennium and the subsequent development of T-cell targeted therapies and tumor necrosis factor (TNF) inhibitors have given patients therapeutic options beyond traditional treatments such as topical steroids, tar preparations, oral systemics, and light …

The key to psoriasis innovation? Dispelling the shadow of the JAK inhibitor Read More »

Trials leave Galapagos’ SIK programme looking under the weather

Galapagos has had to send its SIK inhibitor programme back to the drawing board after its lead compound GLPG3970 has failed two of three clinical trials, adding to a string of disappointments for the Belgian biotech.  Results from a phase 1b study in psoriasis and two phase 2a studies in ulcerative colitis and rheumatoid arthritis …

Trials leave Galapagos’ SIK programme looking under the weather Read More »

Understanding the Link Between Alcohol and Depression

Alcohol abuse is closely correlated with depression. This doesn’t necessarily mean one causes the other, but many people who suffer from depressive disorders turn to alcohol to escape.  On the other side of that coin, those who abuse or overuse alcohol can develop symptoms of depression or exacerbate symptoms that are already present. So, how …

Understanding the Link Between Alcohol and Depression Read More »

Does Oil Pulling Help Dental Plaque or Gingivitis?

Oil pulling is put to the test head-to-head against chlorhexidine mouthwash for oral and dental health measures.  What are the potential risks and benefits of the ancient practice of oil pulling, in which oil is swished or “pulled” between the teeth for 15 minutes or so and then spit out? There are wild, unsubstantiated claims online and even in the medical literature, including the British …

Does Oil Pulling Help Dental Plaque or Gingivitis? Read More »

World Hepatitis Day 2021

Every 30 seconds, a person dies from a hepatitis-related illness. This terrible death toll is why the mantra for World Hepatitis Day (July 28) this year is “Hepatitis Can’t Wait”. Hepatitis is an inflammation of the liver, usually caused by a viral infection. Different hepatitis viruses are transmitted in different ways – for instance, Hepatitis …

World Hepatitis Day 2021 Read More »

AI-driven ‘clock’ predicts aging-related illness and mortality

Scientists in the US have developed an artificial intelligence-powered ‘clock’ that can estimate a person’s chance of developing an illness or dying based on the pattern of cytokines in their blood. The “inflammatory age” or iAge clock – described in the journal Nature Aging – uses a snapshot of the level of chronic inflammation in …

AI-driven ‘clock’ predicts aging-related illness and mortality Read More »

Lilly grabs glucose-sensing insulin tech, buying Protomer in $1bn deal

Eli Lilly bought a stake in Protomer Technologies and its glucose-sensing insulin platform last year, and it must like what it has seen in the programme since then – it has just agreed to buy the company outright.  Pasadena, California-based Protomer is working on proteins that can sense molecular activators in the body and only …

Lilly grabs glucose-sensing insulin tech, buying Protomer in $1bn deal Read More »

ViewPoints Interview: Q BioMed’s Denis Corin Shares Insights on the Agreement to Serve US Department of Defense and Veterans Affairs

In an interview with PharmaShots, Denis Corin, Chief Executive Officer and Chairman of the Board at Q BioMed share his views on the supply agreement for Strontium89 with the US Department of Defense and Veterans Affairs. Shots: BioMed has signed a 5-year agreement to commercially serve the US Department of Veterans Affairs (VA) and Department …

ViewPoints Interview: Q BioMed’s Denis Corin Shares Insights on the Agreement to Serve US Department of Defense and Veterans Affairs Read More »

Biogen reaches across globe and pays $125M to land its next new MS drug

By paying $125 million up front for rights to multiple sclerosis drug candidate orelabrutinib, Biogen secures a place among those companies trying to treat the disease by targeting a particular enzyme highly expressed in the central nervous system. But Biogen still has some catching up to do.

Oil Pulling for Cancer? 

What evidence exists to suggest oil pulling can effectively treat serious diseases, such as paralysis, meningitis, cancer, and AIDS?  I’ve produced videos on how coconut oil is safe to put on your hair or put on your skin, but you certainly don’t want to eat it. In fact, you may not even want to be in the same kitchen when coconut oil is being heated. I don’t know where people got the idea …

Oil Pulling for Cancer?  Read More »

Biogen builds MS pipeline via $125m deal with China’s InnoCare

Biogen has moved to shore up its besieged multiple sclerosis franchise by licensing a BTK inhibitor from Chinese biotech InnoCare currently in mid-stage clinical testing. InnoCare gets $125 million upfront in return for sharing rights to orelabrutinib, an orally-active BTK drug that is able to cross the blood-brain barrier and penetrate the central nervous system. …

Biogen builds MS pipeline via $125m deal with China’s InnoCare Read More »

Novo Nordisk bulks up in rare diseases with $1.2bn Prothena deal

Diabetes giant Novo Nordisk has opened a new front in its rare disease R&D, thanks to an acquisition agreement with Prothena focusing on drugs for ATTR amyloidosis. The Danish drugmaker is paying $100 million upfront for rights to antibody drug PRX004, which is heading for phase 2 trials in cardiomyopathy associated with ATTR amyloidosis, a …

Novo Nordisk bulks up in rare diseases with $1.2bn Prothena deal Read More »

Teen Volunteers Get a Foot in the Door for Nursing Home Careers

Jasmine De Moya, 17, has dreamed for years of working in the medical field, and she yearned to spend time with older people, missing her grandparents, who live in the Dominican Republic. A program sponsored by the New Jewish Home health system in New York City that combines volunteering and free training for entry-level health …

Teen Volunteers Get a Foot in the Door for Nursing Home Careers Read More »

Biogen Signs a License Agreement with Innocare for Orelabrutinib to Treat Multiple Sclerosis

Shots: InnoCare to receive $125M as up front & is eligible to receive ~ $812.5M as development & commercial milestones, following the achievement of definite milestones along with royalties on sales of any product resulting from the collaboration Biogen to get exclusive rights for orelabrutinib to treat MS globally & other autoimmune diseases outside of …

Biogen Signs a License Agreement with Innocare for Orelabrutinib to Treat Multiple Sclerosis Read More »

Pfizer pushes for booster shots as WHO says greed is driving vaccine disparities

• Pharmaceutical company seeks FDA approval for third dose • Companies urged to instead prioritise less wealthy countries After a sharp increase in US Covid cases and amid fears of a surge of the Delta variant, Pfizer on Monday said it was seeking federal authorisation for third doses of its Covid-19 vaccine to be delivered …

Pfizer pushes for booster shots as WHO says greed is driving vaccine disparities Read More »

Why We May Never Know Whether the $56,000-a-Year Alzheimer’s Drug Actually Works

The Food and Drug Administration’s approval in June of a drug purporting to slow the progression of Alzheimer’s disease was widely celebrated, but it also touched off alarms. There were worries in the scientific community about the drug’s mixed results in studies — the FDA’s own expert advisory panel was nearly unanimous in opposing its …

Why We May Never Know Whether the $56,000-a-Year Alzheimer’s Drug Actually Works Read More »

Doctores sopesan pros y contras de recetar la nueva droga para el Alzheimer

Mientras médicos y expertos en políticas de salud debaten los méritos de Aduhelm, el primer fármaco para el Alzheimer aprobado en 18 años, los pacientes simplemente quieren saber: “¿me ayudará?”. Los médicos no tienen una respuesta definitiva. “En cada persona, será absolutamente imposible de predecir”, dijo el doctor Allan Levey, director del Centro de Investigación …

Doctores sopesan pros y contras de recetar la nueva droga para el Alzheimer Read More »

Doctors Weigh Pros and Cons of Prescribing Hot-Button Alzheimer’s Drug

As physicians and health policy experts debate the merits of Aduhelm, the first new drug for Alzheimer’s disease approved in 18 years, patients want to know: “Will this medication help me — and how much?” Doctors explaining the pros and cons of Aduhelm won’t have a definitive answer. “On an individual basis, it will be …

Doctors Weigh Pros and Cons of Prescribing Hot-Button Alzheimer’s Drug Read More »