La Casa Blanca y muchos estadounidenses han depositado sus esperanzas de derrotar a la pandemia de COVID-19 en una vacuna que se está desarrollando a la “velocidad de la luz”. Pero algunos científicos advierten que se espera demasiado, y demasiado pronto. “Todos piensan que COVID-19… Read More »Científicos advierten que se espera demasiado de una vacuna para COVID
Letters to the Editor is a periodic feature. We welcome all comments and will publish a selection. We edit for length and clarity and require full names. On the ‘Subject’ of Vaccine Trial Participants In the piece about the AstraZeneca vaccine trial subject who suffered severe spinal… Read More »Readers and Tweeters Shed Light on Vaccine Trials and Bias in Health Care
The White House and many Americans have pinned their hopes for defeating the COVID-19 pandemic on a vaccine being developed at “warp speed.” But some scientific experts warn they’re all expecting too much, too soon. “Everyone thinks COVID-19 will go away with a vaccine,” said… Read More »Scientists Warn Americans Are Expecting Too Much From a Vaccine
With the ongoing pandemic of COVID-19, there is long wait for the vaccine to be approved. Even after the vaccine gets approved, there is no assurance of the complete eradication of virus. There will still be percentage of people who contract the illness. Therefore, it… Read More »Harnessing The Power of Real World Evidence to Fight COVID-19 Pandemic
Florida’s plan to import cheaper prescription drugs from Canada — designed by Gov. Ron DeSantis and endorsed by President Donald Trump — has tasted its first bitter pill. No private firms bid on Florida’s $30 million contract to set up and operate a drug importation… Read More »Florida Fails to Attract Bidders for Canada Drug Importation Program
While many health technology assessment (HTA) organizations acknowledge that many new treatments reduce the burden placed on caregivers, the value that these new treatments provide is rarely incorporated into formal cost effectiveness analyses. This is the finding from Pennington (2020) based on a review of… Read More »HTA are ignoring the value of reduced caregiver burden
The 21st Century Cures Act required the Food and Drug Administration (FDA) establish a program for evaluating the use of real-world data (RWD) to support the approval of new indications for drugs. Real-world data is typically data from either health insurance claims, electronic health records… Read More »FDA’s use of real-world data
While the definition of real world evidence is still evolving, most proponents associate it with data that is derived from medical practice among heterogeneous sets of patients in the real world setting. It is the integration of data gathered from various sources, such as EHRs,… Read More »REAL-WORLD EVIDENCE: THE GAME CHANGER IN DRUG DEVELOPMENT
During the first presidential debate of 2020, President Donald Trump touted his efforts to curb skyrocketing drug prices and declared that insulin is now “so cheap, it’s like water.” The response on social media was swift, and divided, with some people sharing pharmacy… Read More »Progressive Group Highlights Trump, Tillis Weakness on Insulin Price Tags
The techniques used for the drug delivery are found to be have an enormous impact on the efficacy of the treatment. In fact, the slow progression of the efficacy, has suggested the need of different approaches for the effective delivery of drug to the target… Read More »Inhaled and Intranasal Drug Delivery: A Deeper Look into Service Providers Landscape
Los gigantes farmacéuticos Regeneron y Gilead Sciences obtuvieron el tipo de publicidad que el dinero no puede comprar luego que el presidente Donald Trump tomara sus medicamentos experimentales para tratar su infección por coronavirus, y se declarara completamente recuperado después de dejar el hospital. “Fue… Read More »COVID-19: las farmacéuticas elogiadas por Trump mandan dinero a Biden
Pharmaceutical giants Regeneron and Gilead Sciences got the kind of publicity money can’t buy this week after President Donald Trump took their experimental drugs for his coronavirus infection, left the hospital and pronounced himself fully recovered. “It was, like, unbelievable. I felt good immediately,” Trump… Read More »As Trump Touts His ‘Great’ COVID Drugs, the Pharma Cash Flows to Biden, Not Him
President Donald Trump makes no secret he would like a COVID-19 vaccine to be available before the election. But it’s doubtful that will happen and, even after a vaccine wins FDA approval, there would be a long wait before it’s time to declare victory over… Read More »5 Things to Know About a COVID Vaccine: It Won’t Be a ‘Magic Wand’
Last month, the US Food and Drug Administration published a final rule providing guidance for allowing drug importation from Canada. The drugs have to be approved by the Government of Canada’s Health Canada’s Health Products and Food Branch (HPFB) and can be imported by States… Read More »FDA sets guidelines for drug importation from Canada
For a dad whose infant son was afflicted with a rare seizure disorder, a drug invented in 1952 was indispensable for his boy. It was also indispensable to executives at the pharmaceutical firm that acquired the drug in 2014 — not because it was a… Read More »Old Drug Turned ‘Cash Cow’ as Company Pumped Price to $40K a Vial, Emails Show
Novartis raised EUR 1.85 billion euros of funds through a bond sale earlier this month. A bond sale by a large multinational corporation is not news. What is news is the type of bonds they were: sustainability-linked bonds (SLBs). From the Novartis press release: The… Read More »Linking pharma financial returns to drug access in low-income countries
President Donald Trump accepted the Republican Party’s nomination for president in a 70-minute speech from the South Lawn of the White House on Thursday night. Speaking to a friendly crowd that didn’t appear to be observing social distancing conventions, and with few participants wearing masks,… Read More »Republican Convention, Day 4: Fireworks … and Shining a Light on Trump’s Claims
President Donald Trump has long considered lowering the high cost of prescription drugs to be one of his signature issues, and it is likely to be a talking point he relies on throughout the upcoming campaign. During his afternoon speech Monday ― delivered on the… Read More »Trump Again Claims He’s Bringing Down Drug Prices, But Details of How Are Skimpy
The patients at Dr. Eric Daar’s hospital are at high risk for serious illness from COVID-19, and he’s determined to make sure they’re part of the effort to fight the disease. He also hopes they can protect themselves in the process. When Daar and his… Read More »LA Hospital Seeks Vaccine Trial Participants Among Its Own High-Risk Patients
In a near-empty arena on the river in his hometown of Wilmington, Delaware, former Vice President Joe Biden accepted the Democratic nomination for president, promising hope over fear, fairness over privilege, love over hate. And, he said, “Facts over fiction.” Let’s see about that. Our… Read More »Democratic Convention, Night 4: ‘Facts Over Fiction’ in Biden’s Speech
Can’t see the audio player? Click here to listen on SoundCloud. California Sen. Kamala Harris, the newly named running mate for presumptive Democratic presidential nominee Joe Biden, doesn’t have a lot of background in health policy. But that’s unlikely to prevent Republicans from using her on-again,… Read More »KHN’s ‘What the Health?’: Kamala Harris on Health
COVID-19 is a global pandemic and finding a vaccine for COVID-19 would be a boon to societal. The value would be enormous. One study found that the value would be more than 1.1% of GDP. Since global GDP is $87.7 trillion, the value of a… Read More »What is the “reputational value” of developing a COVID vaccine?
President Trump signed 4 executive orders on drug pricing on July 24, 2020. How are they likely to affect drugs prices? Passing along rebates to patients The one of the executive orders mandates that rebates go to reduce patient cost sharing: These middlemen — health… Read More »Trump executive orders on drug prices: Much ado about nothing?
Imagine this scenario, perhaps a year or two in the future: An effective COVID-19 vaccine is routinely available and the world is moving forward. Life, however, will likely never be the same — particularly for people over 60. That is the conclusion of geriatric medical… Read More »What Seniors Can Expect as Their New Normal in a Post-Vaccine World
With millions of lives on the line, researchers have been working at an unprecedented pace to develop a COVID-19 vaccine. But that speed — and some widely touted breakthroughs — belie the enormous complexity and potential risks involved. Researchers have an incomplete understanding of the… Read More »Fauci Unfazed as Scientists Rely on Unproven Methods to Create COVID Vaccines
Millions of people, including the president of the United States, have seen or shared a video in which a doctor falsely claims there is a cure for the coronavirus, and it’s a medley starring hydroxychloroquine. The video shows several doctors in white coats giving a press conference… Read More »Don’t Fall for This Video: Hydroxychloroquine Is Not a COVID-19 Cure
Can’t see the audio player? Click here to listen on SoundCloud. President Donald Trump’s pivot to a more serious view of the coronavirus pandemic didn’t last long. This week, he was again touting hydroxychloroquine, an antimalarial drug that has not been shown to work against the… Read More »KHN’s ‘What The Health?’: Republicans in COVID Disarray
Hiya! I’m Lauren Olsen, your new Newsletter Editor. That’s right — the totally official, no more fill-ins, always-here-for-you Newsletter Editor. As the replacement for editor extraordinaire Brianna Labuskes, I’m here to tackle all your health news needs. Why yes, you’re right — a pandemic is… Read More »Must-Reads of the Week From Lauren Olsen
Use Nuestro Contenido Este contenido puede usarse de manera gratuita (detalles). A más de cuatro meses del comienzo de la pandemia en los Estados Unidos, ¿qué tan cerca está el país y el mundo de una vacuna segura y efectiva? Científicos dicen que ven un… Read More »Vacuna contra el coronavirus: ¿en qué punto está la investigación?
More than four months into the coronavirus pandemic, how close are the U.S. and the world to a safe and effective vaccine? Scientists say they see steady progress and are expressing cautious optimism that a vaccine could be ready by spring. As of early July,… Read More »A Coronavirus Vaccine: Where Does It Stand?
In drug development, clinical trials typically aim for a population that is representative of the patients who would be eligible for the treatment. While randomized controlled trials (RCTs) typically focus on measuring the average health impact of a drug across this population, a paper Basu… Read More »Treatment effect heterogeneity, self-selection into RCTs, and racial disparities
Antibiotic resistance is a problem. One study from Europe found that in 2015 there were 33,110 deaths attributable to antibiotic resistance; accounting for morbidity as well, antibiotic resistance lead to a a decrease of 874,541 disability-adjusted life years. CDC data show that antibiotic resistant bacteria… Read More »$1 billion antibiotic venture fund launched