Robin Hauser, a pediatrician in Tampa, Fla., got covid in February. What separates her from the vast majority of the tens of millions of other Americans who have come down with the virus is this: She got sick seven weeks after her second dose of… Read More »The Shock and Reality of Catching Covid After Being Vaccinated
Can’t see the audio player? Click here to listen on SoundCloud. The effort to vaccinate Americans against covid-19 took a hit this week. The Centers for Disease Control and Prevention and the Food and Drug Administration jointly called for a pause in use of the vaccine… Read More »KHN’s ‘What the Health?’: Pause and Effect on Covid Vaccines
The cost to bring a drug to market is a hotly debated topic. The costs include not only the costs for basic science and clinical trials. However, one must also take into account the cost of capital (since most cost are incurred up front, but… Read More »Average cost to bring a drug to market is over $1 billion
Chuck Peterson of Omaha, Nebraska, recently experienced a swollen, painful knuckle caused by arthritis. He got a prescription for colchicine. Doctors have used the drug for treating gout and other rheumatic conditions for well over two centuries. When Peterson went to the pharmacy, he was… Read More »The FDA Seeks a New Way to Review Old Drugs Without Causing Prices to Soar
A new drug comes on the market. Is the health benefit worth the cost? What is it’s value? Value assessment frameworks are one way to answer this question. Value frameworks take the evidence of the treatments benefits, risk and cost and output some notion of… Read More »Is value in the eye of the beholder? Value frameworks and inter-rater reliability
Cuatro meses después del lanzamiento del plan de inmunización masiva más grande del país en décadas, ha quedado claro que los mensajes que rodean los esfuerzos de vacunación contra covid-19 son tan importantes como la ciencia que los respalda. Se observó cuando se comenzaron a… Read More »Cuatro respuestas sobre el freno a la vacuna contra covid de Johnson & Johnson
Four months into the largest U.S. vaccine rollout in decades, it’s become clear that the messaging surrounding covid-19 vaccination efforts is as important as the science behind them. That was true when the first covid vaccines were introduced in December at hospitals and nursing homes… Read More »4 Things to Know About the J&J Covid Vaccine Pause
Here are a few highlight’s from the March 2021 report on Medicare Payment Policy from the Medicare Payment Advisory Commission (MedPAC). Leading causes of death The leading cause of death are heart disease, cancer, and respiratory disease. Note that these figures are from 2018. MedPAC… Read More »Highlights from MedPAC’s Spring 2021 Report
Scientists and lawmakers agree that over-the-counter covid tests could allow desk workers to settle back into their cubicles and make it easier to reopen schools and travel. This story also ran on Fortune. It can be republished for free. But even as entrepreneurs race their… Read More »Backed by Millions in Public and Private Cash, Rapid Covid Tests Are Coming to Stores Near You
Can’t see the audio player? Click here to listen on SoundCloud. Congress is out of session, but that hasn’t stopped Democrats from planning their next round of health legislation. Together with President Joe Biden, they are looking at a broad array of possibilities, from allowing Medicare… Read More »KHN’s ‘What the Health?’: Planning for Round Two
A new poll of attitudes toward covid vaccinations shows Americans are growing more enthusiastic about being vaccinated, with the most positive change in the past month occurring among Black Americans. Use Our Content It can be republished for free. About 55% of Black adults said… Read More »Covid Vaccine Hesitancy Drops Among All Americans, New Survey Shows
The development of the first covid vaccines may have seemed to occur at a dizzying pace. After all, scientists identified a new virus and created vaccines to protect against its most severe effects within a year. This story also ran on PolitiFact. It can be… Read More »Ask KHN-PolitiFact: How Can Covid Vaccines Be Safe When They Were Developed So Fast?
¿Podría un antidepresivo que se usa desde hace décadas ser un arma secreta contra covid? Algunos científicos creen que sí, después de que dos pequeños estudios demostraran que la fluvoxamina, que se suele recetar para el trastorno obsesivo compulsivo (TOC), evitara que los participantes desarrollaran… Read More »Medicamentos ya conocidos, y baratos, podrían ser clave para tratar covid
Could a decades-old antidepressant be a secret weapon against covid? A few scientists think so, after two small studies showed that fluvoxamine, typically prescribed for obsessive-compulsive disorder, prevented serious illness in all participants who took the pills soon after developing symptoms. This story also ran… Read More »Scientists Seek Covid Treatment Answers in Cheap, Older Drugs
KHN has put together an interactive tool of significant health policies implemented by the Trump administration using its own authority — executive orders, agency guidance or formal regulations — and is tracking Biden administration and court actions. We will update this chart as actions are… Read More »The Great Undoing: Which of Trump’s Policies Will Biden Reverse?
Can’t see the audio player? Click here to listen on SoundCloud. As questions swirl about the covid vaccine made by AstraZeneca, public health experts are worried the confusion could create more doubts among people already hesitant to get a vaccine. Meanwhile, the first Senate-confirmed officials are… Read More »KHN’s ‘What the Health?’: Getting Down to Work at HHS
Democrats, newly in control of Congress and the White House, are united behind an idea that Republican lawmakers and major drugmakers fiercely oppose: empowering the Department of Health and Human Services to negotiate the prices of brand-name drugs covered by Medicare. This story also ran… Read More »Democrats Eye Medicare Negotiations to Lower Drug Prices
A Senate committee grilled federal officials about the shortage of vaccines to protect Americans against a pandemic virus. Two months later, the U.S. public had lost interest in the virus, and millions of vaccines were sitting in warehouses — although poor countries still needed them.… Read More »The Case for Donating US Covid Vaccines Overseas
Can’t see the audio player? Click here to listen on SoundCloud. The covid relief bill signed by President Joe Biden a week ago includes billions of dollars in new health benefits for consumers. But those benefits may be hard for people to take advantage of because… Read More »KHN’s ‘What the Health?’: ACA Packs More Benefits — And More Confusion
LONG BEACH, Calif. — Cristina Davila wasn’t used to being happy about waiting in line. As a server at the Navy Proof Restaurant and Bar, the specter of covid has weighed heavily on her mind for the past several months. Davila has been especially worried… Read More »‘Super-Sized’ Vaccine Clinic Offers Food Workers Some Relief
The answer to this question likely will be shaped in part by a new multilateral working group that will include not only representatives from the U.S. (U.S. Department of Justice Antitrust Division, and Offices of State Attorneys General), but also Canada (Canadian Competition Bureau), Europe… Read More »What is the FTC’s stance on pharmaceutical mergers?
A number of different federal agencies buy prescription drugs. However, the price at which these pharmaceuticals are purchased varies dramatically. To quantify this variation, a 2021 report from the Congressional Budget Office examines the following prices: Medicare Part D: the prescription drug program for Medicare… Read More »How much does the U.S. federal government pay for pharmaceuticals?
The list price for pharmaceutical price is not what health insurers have to pay. Sure there are patient copayments and coinsurance, but the main reason why insurers don’t pay full list prices are due to pharmacy benefit managers (PBMs). PBMs contract with payers to negotiate… Read More »The size of U.S. pharmaceutical benefits managers (PBMs)
In January, as Mississippi health officials planned for their incoming shipments of covid-19 vaccine, they assessed the state’s most vulnerable: health care workers, of course, and elderly people in nursing homes. But among those who needed urgent protection from the virus ripping across the Magnolia… Read More »High Obesity Rates in Southern States Magnify Covid Threat
Pfizer’s management knew last year there was “a mold issue” at the Kansas facility now slated to produce the drugmaker’s urgently needed covid-19 vaccine, according to a Food and Drug Administration inspection report. This story also ran on The Daily Beast. It can be republished… Read More »Pfizer’s Newest Vaccine Plant Has Persistent Mold Issues, History of Recalls
Can’t see the audio player? Click here to listen on SoundCloud. There’s good news and bad news on covid-19 this week. On the one hand, several million doses of the one-shot Johnson & Johnson vaccine authorized by the FDA for emergency use are already going into… Read More »KHN’s ‘What the Health?’: Good and Not-So-Good News on Covid
By JESSICA DALEY and WAYNE RUSSELL COVID-19 has focused the nation’s attention on the risks associated with complex, global supply chains, particularly related to healthcare products and prescription drugs. While supply disruptions of personal protective equipment (PPE) captured headlines, the pandemic also compromised the drug supply chain. With… Read More »A Plan to Conquer U.S. Drug Shortages
As the speed of covid vaccinations picks up, so do the reports of doses going to waste. And it’s more than just a handful at the end of the day because of a few appointment cancellations. Health officials are trying to rein in waste without… Read More »Accidentally Trashed, Thawed or Expired: Reports of Covid Vaccine Spoilage
En California, la confusión y la comunicación fallida han provocado que algunos padres elegibles y cuidadores familiares de personas con discapacidades sean rechazados en los sitios de vacunación de covid. Oscar Madrigal es uno de esos cuidadores. Sus dos hijos están en el espectro del… Read More »Rechazan a cuidadores familiares en sitios de vacunación contra covid de California
This story is part of a partnership that includes KPCC, NPR and KHN. It can be republished for free. In California, confusion and botched communication has caused some eligible parents and family caregivers of people with disabilities to be turned away at covid vaccination sites.… Read More »In California, Caregivers of People With Disabilities Are Being Turned Away at COVID Vaccine Sites
That is a question considered in the latest edition of The Economist. In the article “How British science came to the rescue“, the magazine notes that COVID-19 had highlighted some of the advantages the UK has. Alongside vast clinical trials, the country has been home… Read More »Is the UK destined to be the next life science hub?
This story also ran on Fortune. It can be republished for free. The World Health Organization greenlighted emergency use of AstraZeneca and Oxford’s covid-19 vaccine this month, following in the steps of the United Kingdom, the European Union and others, who are already injecting it… Read More »Why AstraZeneca and J&J’s Vaccines, In Use the World Over, Are Still on Hold in America
Diversity in clinical trials Recently, the FDA’s Center for Drug Evaluation and Research’s (CDER’s) released its 2020 Drug Trials Snapshots Summary Report. Part of the report examines the demographics of participants in clinical trials for the 53 drugs that FDA approved in 2020 either as… Read More »How representative are clinical trials of the US population?
A few facts: Pharma is increasingly a key driver of US R&D. Pharmaceutical firms share of R&D increased from <10% in the early 1970s to 24% in 2018 (among firms in Compustat data). Moreover, 5 out of top 10 largest R&D spenders in Compustat in… Read More »Why R&D expenses rising and productivity falling could be a good thing
After Billions of Dollars and Dozens of Wartime Declarations, Why Are Vaccines Still in Short Supply?
This story also ran on Fortune. It can be republished for free. The U.S. government has invested billions of dollars in manufacturing, used a wartime act dozens of times to boost supplies and yet there’s still not enough covid vaccine on the way to meet… Read More »After Billions of Dollars and Dozens of Wartime Declarations, Why Are Vaccines Still in Short Supply?
How do you evaluate treatment efficacy and safety outside of the clinical trial setting? This is not just a question of academic interest. In last week’s JAMA, Rubin 2021 writes about some of the challenges of evaluating COVID-19 vaccines outside of a clinical trial setting.… Read More »Use of real-world evidence for regulatory decision-making
Can’t see the audio player? Click here to listen on SoundCloud. An estimated 9 million Americans eligible for free or reduced premium health insurance under the Affordable Care Act have a second chance to sign up for 2021 coverage, since the Biden administration reopened enrollment on… Read More »KHN’s ‘What the Health?’: Open Enrollment, One More Time
Should the US have a formal, centralized health technology assessment (HTA) organization? In the United Kingdom, the National Institute for Health and Care Excellence (NICE) plays this roles and has a significant impact on drug pricing in the UK. However, the UK relies on a… Read More »What kind of HTA does the US need?
“Pfizer and Moderna could share their design with dozens of other pharma companies who stand ready to produce their vaccines and end the pandemic.” — Feb. 3 in a Facebook post This story was produced in partnership with PolitiFact. It can be republished for free. Vaccine… Read More »Can Pfizer and Moderna End the Pandemic by Sharing Their Vaccine Designs? It’s Not that Simple
This story also ran on The Charlotte Observer. It can be republished for free. Kim Wagenaar has been preparing to bring covid-19 vaccines to western North Carolina for months. She’s signed up the community health center she operates in Asheville to receive and distribute the… Read More »Farmworker Camps to Urban Tent Cities: Tailoring Vaccine Info to Where It’s Most Needed
Medicare Part D covers prescription drugs for largely elderly Americans in the U.S. Those who qualify for both Medicare and Medicaid receive Part D drug coverage with no premiums and reduced copayments through the low-income subsidy program (LIS). Although federal and state government pays for… Read More »Medicare Part D: Do beneficiaries shop for high-value plans?
Can’t see the audio player? Click here to listen on SoundCloud. Nearly a year into the pandemic, many public schools are still closed to in-person instruction. But while there is increasing evidence that schools are not a major source of infection, teachers and staffers remain concerned… Read More »KHN’s ‘What the Health?’: Covid and Kids
El 30 de abril se cumplirán los primeros 100 días de mandato del presidente Joe Biden. Este es un punto de referencia que los presidentes suelen establecer para cumplir con las promesas de campaña de alta prioridad. A principios de diciembre, Biden anunció que una… Read More »Cien millones de vacunas contra covid en 100 días no nos hará volver a la normalidad
April 30 will mark the end of the first 100 days of President Joe Biden’s tenure. That’s a benchmark presidents often set for making good on high-priority campaign promises. In early December, Biden announced that one promise would be to get 100 million covid-19 vaccines… Read More »100 Million Covid Shots in 100 Days Doesn’t Get Us Back to Normal
Use Our Content It can be republished for free. When getting vaccinated against covid-19, there’s no sense being picky. You should take the first authorized vaccine that’s offered, experts say. The newest covid vaccine on the horizon, from Johnson & Johnson, is probably a little… Read More »When Your Chance for a Covid Shot Comes, Don’t Worry About the Numbers
Florida, Colorado and several New England states are moving ahead with efforts to import prescription drugs from Canada, a politically popular strategy greenlighted last year by President Donald Trump. But it’s unclear whether the Biden administration will proceed with Trump’s plan for states and the… Read More »States Move Ahead With Canada Drug Importation While Awaiting Signal From Biden
Can’t see the audio player? Click here to listen on SoundCloud. Thursday was “health day” in President Joe Biden’s sprint to launch his presidency, and he signed two executive orders addressing health coverage and women’s reproductive rights. The orders will reopen enrollment under the Affordable Care… Read More »KHN’s ‘What the Health?’: The Long Road to Unwinding Trump Health Policies
How can we best accelerate vaccine availability? This is the question that Ahuja et al. (2021) try to answer in their Becker-Friedman Institute (BFI) working paper. First, they state the obvious: the cost of the COVID-19 pandemic is large. Specifically: Each month, the COVID pandemic… Read More »COVID-19 vaccine manufacturers capture less than 2% of total social value
Remdesivir, Given to Half of Hospitalized Covid Patients in U.S., Is Big Win for Gilead — Boosted by Taxpayers
It was the end of April — just as the U.S. confirmed its millionth covid-19 case and 50,000 deaths — when White House adviser Dr. Anthony Fauci announced “highly significant” news about a drug called remdesivir. That was surprising because the antiviral drug, owned by… Read More »Remdesivir, Given to Half of Hospitalized Covid Patients in U.S., Is Big Win for Gilead — Boosted by Taxpayers
Miles de estadounidenses están muriendo a causa de covid-19, pero los esfuerzos para aumentar la producción de vacunas que potencialmente salvan vidas están en un callejón sin salida. Moderna y Pfizer-BioNTech, los fabricantes de las dos vacunas disponibles hasta el momento, están operando al máximo,… Read More »Por qué ni siquiera la presión presidencial podría acelerar las vacunas contra covid
Americans are dying of covid-19 by the thousands, but efforts to ramp up production of potentially lifesaving vaccines are hitting a brick wall. Vaccine makers Moderna and Pfizer-BioNTech are running their factories full tilt and are under enormous pressure to expand production or collaborate with… Read More »Why Even Presidential Pressure Might Not Get More Vaccine to Market Faster
Joe Biden ran on an expansive health care platform during his 2020 presidential campaign, with a broad array of promises such as adding a government-sponsored health plan to the Affordable Care Act and lowering prescription drug prices. Perhaps most significantly, he pledged to get control… Read More »Health Issues Carried Weight on the Campaign Trail. What Could Biden Do in His First 100 Days?
Can’t see the audio player? Click here to listen on SoundCloud. The reverberations from the Jan. 6 storming of the U.S. Capitol by supporters of President Donald Trump continue. A broad array of business groups, including many from the health industry, are halting contributions to Republicans… Read More »KHN’s ‘What the Health?’: On Capitol Hill, Actions Have Consequences
For Heather Suri, a registered nurse in Virginia, the race to vaccinate Americans against covid has thrown up some unprecedented obstacles. The vaccines themselves are delicate and require a fair bit of focus over time. Consider Moderna’s instructions for preparing its doses: Select the number… Read More »Delicate Covid Vaccines Slow Rollout — Leading to Shots Given Out of Turn or, Worse, Wasted
As the rollout of covid-19 vaccines picks up across the U.S., moving from hospital distribution to pharmacies, pop-up sites and drive-thru clinics, health experts say it’s vital that these expanded venues be prepared to handle rare but potentially life-threatening allergic reactions. “You want to be… Read More »Is Your Covid Vaccine Venue Prepared to Handle Rare, Life-Threatening Reactions?
The party split in Congress is so slim that, even with Democrats technically in the majority, passing major health care legislation will be extremely difficult. So speculation about President-elect Joe Biden’s health agenda has focused on the things he can accomplish using executive authority. Although… Read More »Biden’s First Order of Business May Be to Undo Trump’s Policies, but It Won’t Be Easy
Can’t see the audio player? Click here to listen on SoundCloud. Surprise Democratic victories in Georgia’s two runoff elections this week will give Democrats control of the Senate, which means they will be in charge of both houses of Congress and the White House for the… Read More »KHN’s ‘What the Health?’: Georgia Turns the Senate Blue
This story also ran on Los Angeles Times. It can be republished for free. SAN FRANCISCO — In early 2019, Tom Wolf posted a thank-you on Twitter to the cop who had arrested him the previous spring, when he was homeless and strung out in… Read More »San Francisco Wrestles With Drug Approach as Death and Chaos Engulf Tenderloin
KHN Editor-in-Chief Elisabeth Rosenthal appeared on Diane Rehm’s “On My Mind” podcast on NPR to discuss the bottlenecks that have prevented doses of precious covid-19 vaccine from making it from drugmakers’ factories into patients’ arms. It didn’t have to be this way, she explains. Kaiser… Read More »Listen: How Operation Warp Speed Became a Slow Walk
Ted Howard started taking Truvada a few years ago because he wanted to protect himself against HIV, the virus that causes AIDS. But the daily pill was so pricey he was seriously thinking about giving it up. Under his insurance plan, the former flight attendant… Read More »Many Health Plans Now Must Cover Full Cost of Expensive HIV Prevention Drugs
COLUMBIA, Mo. — A memory haunts Christina Fuhrman: the image of her toddler Pearl lying pale and listless in a hospital bed, tethered to an IV to keep her hydrated as she struggled against a superbug infection. “She survived by the grace of God,” Fuhrman… Read More »Children’s Hospitals Are Partly to Blame as Superbugs Increasingly Attack Kids
This story also ran on Fortune. It can be republished for free. Sharon Clark is able to get her life-sustaining cancer drug, Pomalyst — priced at more than $18,000 for a 28-day supply — only because of the generosity of patient assistance foundations. Clark, 57,… Read More »Seniors Face Crushing Drug Costs as Congress Stalls on Capping Medicare Out-Of-Pockets
This story also ran on The New York Times. It can be republished for free. WASHINGTON — Even before there was a vaccine, some seasoned doctors and public health experts warned, Cassandra-like, that its distribution would be “a logistical nightmare.” After Week 1 of the… Read More »Analysis: Some Said the Vaccine Rollout Would Be a ‘Nightmare.’ They Were Right.
Can’t see the audio player? Click here to listen on SoundCloud. COVID-19 was the dominant — but not the only — health policy story of 2020. In this special year-in-review episode of KHN’s “What the Health?” podcast, panelists look back at some of the biggest non-coronavirus… Read More »KHN’s ‘What the Health?’: 2020 in Review — It Wasn’t All COVID
In late summer, as researchers accelerated the first clinical trials of COVID-19 vaccines for humans, a group of scientists in Colorado worked to inoculate a far more fragile species. About 120 black-footed ferrets, among the most endangered mammals in North America, were injected with an… Read More »At Risk of Extinction, Black-Footed Ferrets Get Experimental COVID Vaccine
One tray of COVID-19 vaccine from pharmaceutical giant Pfizer contains 975 doses — way too many for a rural hospital in Arkansas. But with the logistical gymnastics required to safely get the Pfizer vaccine to rural health care workers, splitting the trays into smaller shipments… Read More »Inside the First Chaotic Days of the Effort to Vaccinate America
For developing an improved understanding of the interactions of individual cells within their microenvironment, advanced molecular probing solutions are being used by researchers across the globe. In this context, high-throughput single-cell analysis, has emerged as a powerful analytical technique for studying individual cells, enabling researchers… Read More »Single-Cell Sequencing: The New Era of Gene Expression Analysis
That is the title of an article by Angela Maas in Radar on Specialty pharmacy (reprinted here). A few excerpts: “Although state governments frequently pay for health care through programs such as Medicaid, in the past, state governments have not manufactured drugs,” says Jason Shafrin,… Read More »Law Will Allow Calif. to Produce, Distribute Biosimilars, Generics
Se espera que los trabajadores de salud de primera línea, así como los residentes y el personal de los hogares de adultos mayores, reciban las dosis iniciales de la vacuna contra COVID. La cuestión más espinosa es averiguar quiénes serán los siguientes. La respuesta probablemente… Read More »Agrícolas, bomberos y azafatas buscan estar entre los primeros en recibir la vacuna
Use Our Content It can be republished for free. High stakes and big challenges await as the U.S. prepares to roll out vaccines against COVID-19, with front-line health care workers and vulnerable nursing home residents recommended as the top priority. Doses could be on their… Read More »Supply Is Limited and Distribution Uncertain as COVID Vaccine Rolls Out
With front-line health workers and nursing home residents and staff expected to get the initial doses of COVID vaccines, the thornier question is figuring out who goes next. The answer will likely depend on where you live. While an influential federal advisory board is expected… Read More »Farmworkers, Firefighters and Flight Attendants Jockey for Vaccine Priority
How do you incentivize pharmaceutical companies and researchers to develop new drugs for rare diseases? Drug development is expensive and–by definition–rare diseases have a small market. One solution to this problem is that governments have used orphan drug policies to provide monetary incentives for innovators… Read More »Orphan Drug Policies Around the World
Americans have made no secret of their skepticism of COVID-19 vaccines this year, with fears of political interference and a “warp speed” timeline blunting confidence in the shots. As recently as September, nearly half of U.S. adults said they didn’t intend to be inoculated. But… Read More »Demand for COVID Vaccines Expected to Get Heated — And Fast
Torey Watson is trained as a pharmacist but aims to do more than simply fill prescriptions. Pharmax Pharmacy — a small drugstore chain where Watson works as a clinical services coordinator, about an hour and 30 minutes southwest of St. Louis — will soon allow… Read More »Feds Look to Pharmacists to Boost Childhood Immunization Rates
The post New COVID vaccines could revolutionize vaccination appeared first on Healthy Debate.
This is the question that a recent paper by Chorniy et al. (2020) attempt to answer. This issue is clearly very relevant as the UK recently has approved the Pfizer/BioNTech vaccine for COVID-19 before the US. Unlike most studies that attempt to examine the relationship… Read More »What is the impact of FDA review time on pharmaceutical R&D investments?
Shots: Boston Scientific signs an agreement with Stark International and SERB SAS to sell its BTG specialty pharma business for $800M in cash. The transaction is expected to close in H1’21 The agreement includes the transfer of 5 facilities & ~280 employees globally. This transaction… Read More »Boston Scientific to Divest BTG’s Specialty Pharma Business for ~$800M
Dr. Jacqueline Chu considered the man with a negative coronavirus test on the other end of the phone, and knew, her heart dropping, that the test result was not enough to clear him for work. The man was a grocery store clerk — an essential… Read More »How COVID-19 Highlights the Uncertainty of Medical Testing
I’ve mentioned this in a number of previous posts, but large scale importation from Canada won’t work to bring down US drugs prices. The US market is too large and Canada does not have the supply to meet US demand. Further, policies proposing drug importation… Read More »Drug importation from Canada won’t work
April 16 was a big day for Moderna, a Massachusetts biotech company on the verge of becoming a front-runner in the U.S. government’s race for a coronavirus vaccine. It had received roughly half a billion dollars in federal funding to develop a COVID shot that… Read More »How Pharma Money Colors Operation Warp Speed’s Quest to Defeat COVID
If we break down the numbers, it turns out that medical costs–rather than pharmacy cost–are the key drivers of differences in health care spending per capita. This is the findings from Kaiser Family Foundation (KFF) study comparing US spending against an average from 9 other… Read More »Why does the US spend so much more on health care than other countries?
Back in March, just as anxiety over COVID-19 began spreading across the U.S., Erinn Baldeschwiler of La Conner, Washington, found herself facing her own private dread. Just 48 and the mother of two teenagers, Baldeschwiler was diagnosed with stage 4 metastatic breast cancer after discovering… Read More »New Legal Push Aims to Speed Magic Mushrooms to Dying Patients
The post Pregnant women warned to avoid some pain-relief drugs appeared first on Healthy Debate.
Health insurance companies will have to give their customers estimated out-of-pocket costs for prescription drugs and disclose to the public the negotiated prices they pay for drugs, under an unexpected new Trump administration rule. The administration said those requirements, part of a broader rule issued… Read More »Surprise Federal Drug Rule Directs Insurers to Reveal What They Pay for Prescription Drugs
When he started researching a troublesome childhood infection nearly four decades ago, virologist Dr. Barney Graham, then at Vanderbilt University, had no inkling his federally funded work might be key to deliverance from a global pandemic. Yet nearly all the vaccines advancing toward possible FDA… Read More »Government-Funded Scientists Laid the Groundwork for Billion-Dollar Vaccines
NEW YORK — Mike Angevine lives in constant pain. For a decade the 37-year-old has relied on opioids to manage his chronic pancreatitis, a disease with no known cure. But in January, Angevine’s pharmacy on Long Island ran out of oxymorphone and he couldn’t find… Read More »Patients Struggle to Find Prescription Opioids After NY Tax Drives Out Suppliers
¿Es hora de discutir los potenciales efectos secundarios de las vacunas para COVID? Científicos dicen que sí
Se espera que la farmacéutica Pfizer solicite permiso federal para lanzar su vacuna para COVID-19 a fines de noviembre. Una medida que promete acorralar la pandemia, pero que no ofrece mucho tiempo para asegurarse de que los consumidores estén bien informados. Esta vacuna, y probablemente… Read More »¿Es hora de discutir los potenciales efectos secundarios de las vacunas para COVID? Científicos dicen que sí
Drugmaker Pfizer is expected to seek federal permission to release its COVID-19 vaccine by the end of November, a move that holds promise for quelling the pandemic, but also sets up a tight time frame for making sure consumers understand what it will mean to… Read More »Time to Discuss Potentially Unpleasant Side Effects of COVID Shots? Scientists Say Yes.
El anuncio de Pfizer de que su vacuna contra COVID-19 prevendría que nueve de cada 10 personas contraigan la enfermedad hizo que el precio de sus acciones se disparara. Muchos titulares describieron a la vacuna como si fuera la liberación de la pandemia, aunque se… Read More »Cinco preguntas críticas sobre la vacuna contra COVID-19 de Pfizer
Pfizer’s announcement on Monday that its COVID-19 shot appears to keep nine in 10 people from getting the disease sent its stock price rocketing. Many news reports described the vaccine as if it were our deliverance from the pandemic, even though few details were released.… Read More »Five Important Questions About Pfizer’s COVID-19 Vaccine
Dr. Matthew Lewin, founder of the Center for Exploration and Travel Health at the California Academy of Sciences, was researching snakebite treatments in rural locations in preparation for an expedition to the Philippines in 2011. The story of a renowned herpetologist from the academy, Joseph… Read More »Search for a Snakebite Drug Might Lead to a COVID Treatment, Too
Specialty drugs are often injectibles, biologic drugs, or other drugs that require specialized administration, handling, or ongoing clinical assessment. Specialty drugs are often more expensive than standard pharmaceuticals. As the use of specialty pharmaceuticals has become more common, a paper by Hill, Miller and Ding… Read More »Spending on specialty drugs: 2010-2017
The Department of Veterans Affairs is recruiting 8,000 volunteers for the Phase 3 clinical trials of at least four COVID-19 vaccine candidates at 20 federal medical facilities across the U.S., according to officials with the VA and Operation Warp Speed, the Trump administration’s initiative to… Read More »VA Joins Pentagon in Recruiting Volunteers for COVID Vaccine Trials
If they’ve been listening to President Donald Trump, seniors may be expecting a $200 debit card in the mail any day now to help them pay for prescription drugs. He promised as much this month, saying his administration soon will mail the drug cards to… Read More »A $200 Debit Card Won’t Do Much for Seniors’ Drug Costs
La Casa Blanca y muchos estadounidenses han depositado sus esperanzas de derrotar a la pandemia de COVID-19 en una vacuna que se está desarrollando a la “velocidad de la luz”. Pero algunos científicos advierten que se espera demasiado, y demasiado pronto. “Todos piensan que COVID-19… Read More »Científicos advierten que se espera demasiado de una vacuna para COVID
Letters to the Editor is a periodic feature. We welcome all comments and will publish a selection. We edit for length and clarity and require full names. On the ‘Subject’ of Vaccine Trial Participants In the piece about the AstraZeneca vaccine trial subject who suffered severe spinal… Read More »Readers and Tweeters Shed Light on Vaccine Trials and Bias in Health Care
The White House and many Americans have pinned their hopes for defeating the COVID-19 pandemic on a vaccine being developed at “warp speed.” But some scientific experts warn they’re all expecting too much, too soon. “Everyone thinks COVID-19 will go away with a vaccine,” said… Read More »Scientists Warn Americans Are Expecting Too Much From a Vaccine
With the ongoing pandemic of COVID-19, there is long wait for the vaccine to be approved. Even after the vaccine gets approved, there is no assurance of the complete eradication of virus. There will still be percentage of people who contract the illness. Therefore, it… Read More »Harnessing The Power of Real World Evidence to Fight COVID-19 Pandemic
Florida’s plan to import cheaper prescription drugs from Canada — designed by Gov. Ron DeSantis and endorsed by President Donald Trump — has tasted its first bitter pill. No private firms bid on Florida’s $30 million contract to set up and operate a drug importation… Read More »Florida Fails to Attract Bidders for Canada Drug Importation Program
While many health technology assessment (HTA) organizations acknowledge that many new treatments reduce the burden placed on caregivers, the value that these new treatments provide is rarely incorporated into formal cost effectiveness analyses. This is the finding from Pennington (2020) based on a review of… Read More »HTA are ignoring the value of reduced caregiver burden
The 21st Century Cures Act required the Food and Drug Administration (FDA) establish a program for evaluating the use of real-world data (RWD) to support the approval of new indications for drugs. Real-world data is typically data from either health insurance claims, electronic health records… Read More »FDA’s use of real-world data
While the definition of real world evidence is still evolving, most proponents associate it with data that is derived from medical practice among heterogeneous sets of patients in the real world setting. It is the integration of data gathered from various sources, such as EHRs,… Read More »REAL-WORLD EVIDENCE: THE GAME CHANGER IN DRUG DEVELOPMENT
During the first presidential debate of 2020, President Donald Trump touted his efforts to curb skyrocketing drug prices and declared that insulin is now “so cheap, it’s like water.” The response on social media was swift, and divided, with some people sharing pharmacy… Read More »Progressive Group Highlights Trump, Tillis Weakness on Insulin Price Tags
The techniques used for the drug delivery are found to be have an enormous impact on the efficacy of the treatment. In fact, the slow progression of the efficacy, has suggested the need of different approaches for the effective delivery of drug to the target… Read More »Inhaled and Intranasal Drug Delivery: A Deeper Look into Service Providers Landscape
Los gigantes farmacéuticos Regeneron y Gilead Sciences obtuvieron el tipo de publicidad que el dinero no puede comprar luego que el presidente Donald Trump tomara sus medicamentos experimentales para tratar su infección por coronavirus, y se declarara completamente recuperado después de dejar el hospital. “Fue… Read More »COVID-19: las farmacéuticas elogiadas por Trump mandan dinero a Biden
Pharmaceutical giants Regeneron and Gilead Sciences got the kind of publicity money can’t buy this week after President Donald Trump took their experimental drugs for his coronavirus infection, left the hospital and pronounced himself fully recovered. “It was, like, unbelievable. I felt good immediately,” Trump… Read More »As Trump Touts His ‘Great’ COVID Drugs, the Pharma Cash Flows to Biden, Not Him
President Donald Trump makes no secret he would like a COVID-19 vaccine to be available before the election. But it’s doubtful that will happen and, even after a vaccine wins FDA approval, there would be a long wait before it’s time to declare victory over… Read More »5 Things to Know About a COVID Vaccine: It Won’t Be a ‘Magic Wand’
Last month, the US Food and Drug Administration published a final rule providing guidance for allowing drug importation from Canada. The drugs have to be approved by the Government of Canada’s Health Canada’s Health Products and Food Branch (HPFB) and can be imported by States… Read More »FDA sets guidelines for drug importation from Canada
For a dad whose infant son was afflicted with a rare seizure disorder, a drug invented in 1952 was indispensable for his boy. It was also indispensable to executives at the pharmaceutical firm that acquired the drug in 2014 — not because it was a… Read More »Old Drug Turned ‘Cash Cow’ as Company Pumped Price to $40K a Vial, Emails Show
Novartis raised EUR 1.85 billion euros of funds through a bond sale earlier this month. A bond sale by a large multinational corporation is not news. What is news is the type of bonds they were: sustainability-linked bonds (SLBs). From the Novartis press release: The… Read More »Linking pharma financial returns to drug access in low-income countries
President Donald Trump accepted the Republican Party’s nomination for president in a 70-minute speech from the South Lawn of the White House on Thursday night. Speaking to a friendly crowd that didn’t appear to be observing social distancing conventions, and with few participants wearing masks,… Read More »Republican Convention, Day 4: Fireworks … and Shining a Light on Trump’s Claims
President Donald Trump has long considered lowering the high cost of prescription drugs to be one of his signature issues, and it is likely to be a talking point he relies on throughout the upcoming campaign. During his afternoon speech Monday ― delivered on the… Read More »Trump Again Claims He’s Bringing Down Drug Prices, But Details of How Are Skimpy
The patients at Dr. Eric Daar’s hospital are at high risk for serious illness from COVID-19, and he’s determined to make sure they’re part of the effort to fight the disease. He also hopes they can protect themselves in the process. When Daar and his… Read More »LA Hospital Seeks Vaccine Trial Participants Among Its Own High-Risk Patients
In a near-empty arena on the river in his hometown of Wilmington, Delaware, former Vice President Joe Biden accepted the Democratic nomination for president, promising hope over fear, fairness over privilege, love over hate. And, he said, “Facts over fiction.” Let’s see about that. Our… Read More »Democratic Convention, Night 4: ‘Facts Over Fiction’ in Biden’s Speech
Can’t see the audio player? Click here to listen on SoundCloud. California Sen. Kamala Harris, the newly named running mate for presumptive Democratic presidential nominee Joe Biden, doesn’t have a lot of background in health policy. But that’s unlikely to prevent Republicans from using her on-again,… Read More »KHN’s ‘What the Health?’: Kamala Harris on Health
COVID-19 is a global pandemic and finding a vaccine for COVID-19 would be a boon to societal. The value would be enormous. One study found that the value would be more than 1.1% of GDP. Since global GDP is $87.7 trillion, the value of a… Read More »What is the “reputational value” of developing a COVID vaccine?
President Trump signed 4 executive orders on drug pricing on July 24, 2020. How are they likely to affect drugs prices? Passing along rebates to patients The one of the executive orders mandates that rebates go to reduce patient cost sharing: These middlemen — health… Read More »Trump executive orders on drug prices: Much ado about nothing?
Imagine this scenario, perhaps a year or two in the future: An effective COVID-19 vaccine is routinely available and the world is moving forward. Life, however, will likely never be the same — particularly for people over 60. That is the conclusion of geriatric medical… Read More »What Seniors Can Expect as Their New Normal in a Post-Vaccine World
With millions of lives on the line, researchers have been working at an unprecedented pace to develop a COVID-19 vaccine. But that speed — and some widely touted breakthroughs — belie the enormous complexity and potential risks involved. Researchers have an incomplete understanding of the… Read More »Fauci Unfazed as Scientists Rely on Unproven Methods to Create COVID Vaccines
Millions of people, including the president of the United States, have seen or shared a video in which a doctor falsely claims there is a cure for the coronavirus, and it’s a medley starring hydroxychloroquine. The video shows several doctors in white coats giving a press conference… Read More »Don’t Fall for This Video: Hydroxychloroquine Is Not a COVID-19 Cure
Can’t see the audio player? Click here to listen on SoundCloud. President Donald Trump’s pivot to a more serious view of the coronavirus pandemic didn’t last long. This week, he was again touting hydroxychloroquine, an antimalarial drug that has not been shown to work against the… Read More »KHN’s ‘What The Health?’: Republicans in COVID Disarray
Hiya! I’m Lauren Olsen, your new Newsletter Editor. That’s right — the totally official, no more fill-ins, always-here-for-you Newsletter Editor. As the replacement for editor extraordinaire Brianna Labuskes, I’m here to tackle all your health news needs. Why yes, you’re right — a pandemic is… Read More »Must-Reads of the Week From Lauren Olsen
Use Nuestro Contenido Este contenido puede usarse de manera gratuita (detalles). A más de cuatro meses del comienzo de la pandemia en los Estados Unidos, ¿qué tan cerca está el país y el mundo de una vacuna segura y efectiva? Científicos dicen que ven un… Read More »Vacuna contra el coronavirus: ¿en qué punto está la investigación?
More than four months into the coronavirus pandemic, how close are the U.S. and the world to a safe and effective vaccine? Scientists say they see steady progress and are expressing cautious optimism that a vaccine could be ready by spring. As of early July,… Read More »A Coronavirus Vaccine: Where Does It Stand?
In drug development, clinical trials typically aim for a population that is representative of the patients who would be eligible for the treatment. While randomized controlled trials (RCTs) typically focus on measuring the average health impact of a drug across this population, a paper Basu… Read More »Treatment effect heterogeneity, self-selection into RCTs, and racial disparities
Antibiotic resistance is a problem. One study from Europe found that in 2015 there were 33,110 deaths attributable to antibiotic resistance; accounting for morbidity as well, antibiotic resistance lead to a a decrease of 874,541 disability-adjusted life years. CDC data show that antibiotic resistant bacteria… Read More »$1 billion antibiotic venture fund launched