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Disparities in the Use of Guideline-Based Pharmacotherapy Exist for Atherosclerotic Cardiovascular Disease and Heart Failure Patients Who Have Intellectual/Developmental Disabilities in a Commercially Insured Database

Annals of Pharmacotherapy, Volume 54, Issue 10, Page 958-966, October 2020. Background:Patients who have intellectual/developmental disabilities (IDDs) develop atherosclerotic cardiovascular disease (ASCVD) or heart failure (HF) at rates similar to or higher than the general population. They also face disparities accessing and using health care services.Objective:To determine if disparities exist in the use of guideline-based …

Disparities in the Use of Guideline-Based Pharmacotherapy Exist for Atherosclerotic Cardiovascular Disease and Heart Failure Patients Who Have Intellectual/Developmental Disabilities in a Commercially Insured Database Read More »

Disparities in the Use of Guideline-Based Pharmacotherapy Exist for Atherosclerotic Cardiovascular Disease and Heart Failure Patients Who Have Intellectual/Developmental Disabilities in a Commercially Insured Database

Annals of Pharmacotherapy, Ahead of Print. Background: Patients who have intellectual/developmental disabilities (IDDs) develop atherosclerotic cardiovascular disease (ASCVD) or heart failure (HF) at rates similar to or higher than the general population. They also face disparities accessing and using health care services. Objective: To determine if disparities exist in the use of guideline-based pharmacotherapy (GBP) …

Disparities in the Use of Guideline-Based Pharmacotherapy Exist for Atherosclerotic Cardiovascular Disease and Heart Failure Patients Who Have Intellectual/Developmental Disabilities in a Commercially Insured Database Read More »

Disparities in the Use of Guideline-Based Pharmacotherapy Exist for Atherosclerotic Cardiovascular Disease and Heart Failure Patients Who Have Intellectual/Developmental Disabilities in a Commercially Insured Database

Annals of Pharmacotherapy, Ahead of Print. Background: Patients who have intellectual/developmental disabilities (IDDs) develop atherosclerotic cardiovascular disease (ASCVD) or heart failure (HF) at rates similar to or higher than the general population. They also face disparities accessing and using health care services. Objective: To determine if disparities exist in the use of guideline-based pharmacotherapy (GBP) …

Disparities in the Use of Guideline-Based Pharmacotherapy Exist for Atherosclerotic Cardiovascular Disease and Heart Failure Patients Who Have Intellectual/Developmental Disabilities in a Commercially Insured Database Read More »

Research Headlines – Keeping children safe in stressful times

A free parenting programme based on EU-funded research has won a 2019 Horizon Impact Award for its success in helping families to avoid child abuse in low-and middle-income countries. Now parents everywhere can access online tips to cope with COVID-19 lockdown life.

Research Headlines – Keeping children safe in stressful times

A free parenting programme based on EU-funded research has won a 2019 Horizon Impact Award for its success in helping families to avoid child abuse in low-and middle-income countries. Now parents everywhere can access online tips to cope with COVID-19 lockdown life.

Impact of Automated Targeted Medication Review Electronic Alerts to Reduce Potentially Inappropriate Medication Prescribing Among Medicare Enrolled Patients With Dementia

Annals of Pharmacotherapy, Volume 54, Issue 10, Page 967-974, October 2020. Background:Background:Finding ways to reduce prescribing of potentially inappropriate medications (PIMs) among patients with dementia is necessary.Objectives:To evaluate an automated targeted medication review (TMR) service to reduce PIM prescribing among patients with dementia.Methods:This was a retrospective observational analysis of patients in a Medication Therapy Management …

Impact of Automated Targeted Medication Review Electronic Alerts to Reduce Potentially Inappropriate Medication Prescribing Among Medicare Enrolled Patients With Dementia Read More »

Impact of Automated Targeted Medication Review Electronic Alerts to Reduce Potentially Inappropriate Medication Prescribing Among Medicare Enrolled Patients With Dementia

Annals of Pharmacotherapy, Ahead of Print. Background: Background:Finding ways to reduce prescribing of potentially inappropriate medications (PIMs) among patients with dementia is necessary. Objectives: To evaluate an automated targeted medication review (TMR) service to reduce PIM prescribing among patients with dementia. Methods: This was a retrospective observational analysis of patients in a Medication Therapy Management …

Impact of Automated Targeted Medication Review Electronic Alerts to Reduce Potentially Inappropriate Medication Prescribing Among Medicare Enrolled Patients With Dementia Read More »

Impact of Automated Targeted Medication Review Electronic Alerts to Reduce Potentially Inappropriate Medication Prescribing Among Medicare Enrolled Patients With Dementia

Annals of Pharmacotherapy, Ahead of Print. Background: Background:Finding ways to reduce prescribing of potentially inappropriate medications (PIMs) among patients with dementia is necessary. Objectives: To evaluate an automated targeted medication review (TMR) service to reduce PIM prescribing among patients with dementia. Methods: This was a retrospective observational analysis of patients in a Medication Therapy Management …

Impact of Automated Targeted Medication Review Electronic Alerts to Reduce Potentially Inappropriate Medication Prescribing Among Medicare Enrolled Patients With Dementia Read More »

Clinical Genomics Data for Precision Medicine

Genomic data—information about the complete set of genes that make up each individual—have the potential to revolutionize healthcare and usher in a new era of precision medicine and scientific discovery. However, there is currently no standard way of presenting genomic data, and the standards for integrating those data with electronic health record (EHR) and other …

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Q & A with Anupam B. Jena

2020 TEDMED Speaker Anupam B. Jena shares the power of creative observations in his Talk “The profound difference between seeing and looking.” In response to his Talk and his segment on TED Radio Hour, TEDMED spoke with Anupam about observing the changing world during COVID-19. TEDMED: Given the rise of COVID-19, what questions that are …

Q & A with Anupam B. Jena

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How to Treat Hiccups

Nearly everyone has experienced hiccups, but what exactly are they? It used to be thought that a hiccup is just a simple muscle spasm of the diaphragm, but that was apparently disproven more than 40 years ago. Instead, hiccups involve a complex, orchestrated pattern of muscle contractions. But, why? Hiccups might be a leftover from …

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Pharmacovigilance at Glance :- Safety Monitoring

AUTHORS : Girjesh Vishwakarma*, Dr.Surendra Kumar Jain   Sagar Institute of Research & Technology – Pharmacy Opp. Sagar Estate, Ayodhya By Pass Road, Bhopal – 462 041 (MP) Gv1448@gmail.com ABSTRACT :  Now a day’s usage of drugs has been increasing day by day and pharmaceutical companies are developing new drug products and humans begin taking …

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How Innovative Trial Models Keep Your Active Trials on Track

Provided by: Elligo Health Research https://www.elligohealthresearch.com/ The ongoing COVID-19 pandemic continues to highlight the need for secure virtual capabilities and decentralized/hybrid approaches to clinical research models. Not only do these solutions maintain the momentum of current studies in times of disruption, but more importantly, they ensure that patients continue to receive access to life-saving treatments …

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Campaign guide

20/04/2020 Campaign guide Download in:EN

Campaign poster

20/04/2020 Campaign poster Download in:EN

Salted Caramel Shakeology Is Sold Out!

Salted Caramel Shakeology has officially SOLD OUT in the U.S. and Canada. We’re so excited for those who were able to order this new flavor and overwhelmed with how fast this sold out! Talk to your Team Beachbody Coach or visit teambeachbody.com to check out our other delicious Shakeology flavors. Summer means long, sunny days, sunglasses, sunscreen …

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Vein Practice Marketing Strategies to Implement Now

Marketing Strategies to Implement Now For Your Vein Practice A Webinar Sponsored by the American Vein and Lymphatic Society COVID-19 has caused massive economic disruption to virtually every kind of business, including vein practices. Which marketing strategies should you begin now, and which should you implement in the coming months as the crisis slowly subsides? …

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When to Seek Emergency Care

We are all doing our part to help slow the spread during the COVID-19 pandemic. Physical distancing is important to prevent the spread of COVID-19, but it is equally important that you monitor your health and know when to seek emergency medical care for serious symptoms that are not related to COVID-19. You may be …

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Mindset Menu Cooking Show

In just a couple of years, the 2B Mindset nutrition program has helped hundreds of thousands of people lose weight happily — and actually keep the pounds off! And now, Ilana Muhlstein, M.S, R.D.N., and creator of 2B Mindset, plans to continue the positive momentum with her brand-new cooking channel, Mindset Menu. Mindset Menu is available …

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Breaking new ground in healthcare data

  The pandemic crisis has been focusing minds in healthcare and demonstrating the possibilities to innovate faster.   Pharma should remember this in the aftermath, says Sanofi Pasteur’s David Loew, not least because, given the economic damage of a near global lockdown, governments can soon be expected to be on the hunt for savings from …

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Takeaways from My Webinar on COVID-19

On December 30, 2019, Dr. Li Wenliang, an ophthalmologist at Wuhan Central Hospital in the Hubei province of China, messaged his fellow physicians, alerting them to the appearance of what he thought as SARS. Thirty-nine days later, after becoming infected with the very virus he tried to warn his colleagues about, he was dead at …

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How can you collect overdue payments and get fair compensation for your services?

The Hidden Costs of Accounts Receivable Many businesses extend credit to customers, to provide the services and products they need.  According to a 2019 report on the economic well-being of U.S. households, 33% of adults are either unable to pay their bills or are one modest financial setback away from hardship. 4 in 10 adults …

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Need of online pharmacy during covid-19 lockdown

The global Online Pharmacy market is anticipated to rise at a considerable rate. The consumers are preferring to purchase medicine online due to covid-19 lockdown.  Governments are taking all essential steps for protecting lives by imposing lockdowns, testing, segregation, and treatment. At the same time also restricting outdoor movement except for supplying and procuring essential …

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Building a bridge to a COVID-19 vaccine

Regeneron has shared high hopes for its two candidates in the fight against COVID-19 on the first day of the four-day eyeforpharma Philadelphia virtual event.   George Yancopolous, President and Chief Scientific Officer at Regeneron, revealed that the company expected to have a good idea of the prospects for Kevzara, one of the two therapies …

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What About the Sodium in Miso?

According to the second World Cancer Research Fund/American Institute for Cancer Research expert report, “[s]alt is a probable cause of stomach cancer,” one of the world’s leading cancer killers. If the report’s estimate of an 8 percent increase in risk for every extra gram of salt a day is correct, then in a country like …

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Digital Content opportunities

Channels:  Access and Evidence Medical Multichannel Patients and Medical Clinical Column Commercial Image:  URL:  https://eloqua.eyeforpharma.com/LP=27091?extsource=efp_website Exclude from Homepage:  No

SHOULD WE CUT BACK ON CAFFEINE?

AUTHORS : P.Tulasi, M.Akshara, M.Manisha Reddy, M. Hiranmai, M. Anusha Reddy. Sarojini Naidu Vanita Pharmacy Maha Vidyalaya, Hyderabad ABSTRACT : We aimed to explore on different effects of ingestion of caffeine. We mainly focused on the advantages and disadvantages of caffeine ingestion along with healthy dosage and alternative for caffeine. We conclude that ingestion of …

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Customer Success: Formulary Management

In response to customer requests, we’ve built some new tools for formulary management. You can preview these tools at: Recent Generic Drug Launches Upcoming 180-Day Patent Challenge Exclusivity Expirations Anticipate… The post Customer Success: Formulary Management appeared first on DrugPatentWatch – Make Better Decisions.

Weight Outcomes With Empagliflozin as Compared With Liraglutide in Veterans With Type 2 Diabetes Mellitus

Annals of Pharmacotherapy, Volume 54, Issue 10, Page 981-987, October 2020. Background:Glucagon-like peptide-1 agonists and sodium glucose cotransporter 2 inhibitors are associated with weight loss and improved cardiovascular outcomes, and are increasingly used in pharmacotherapy for type 2 diabetes mellitus (T2DM).Objectives:To compare weight loss outcomes of empagliflozin and liraglutide in patients with T2DM and overweight/obesity …

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Weight Outcomes With Empagliflozin as Compared With Liraglutide in Veterans With Type 2 Diabetes Mellitus

Annals of Pharmacotherapy, Ahead of Print. Background: Glucagon-like peptide-1 agonists and sodium glucose cotransporter 2 inhibitors are associated with weight loss and improved cardiovascular outcomes, and are increasingly used in pharmacotherapy for type 2 diabetes mellitus (T2DM). Objectives: To compare weight loss outcomes of empagliflozin and liraglutide in patients with T2DM and overweight/obesity not yet …

Weight Outcomes With Empagliflozin as Compared With Liraglutide in Veterans With Type 2 Diabetes Mellitus Read More »

Weight Outcomes With Empagliflozin as Compared With Liraglutide in Veterans With Type 2 Diabetes Mellitus

Annals of Pharmacotherapy, Ahead of Print. Background: Glucagon-like peptide-1 agonists and sodium glucose cotransporter 2 inhibitors are associated with weight loss and improved cardiovascular outcomes, and are increasingly used in pharmacotherapy for type 2 diabetes mellitus (T2DM). Objectives: To compare weight loss outcomes of empagliflozin and liraglutide in patients with T2DM and overweight/obesity not yet …

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From reactive to predictive: Concerto’s new compositions

In his 2016 book Healthcare Disrupted, Dr Jeff Elton sketched out how healthcare would move from being reactive to proactive thanks to the ubiquity of electronic health records (EHRs) and other datasets.    That future is now upon us, says Elton, CEO of precision oncology business Concerto HealthAI. whose mission is to combine RWE and …

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How to Prevent the Infection that May Trigger Type 1 Diabetes

The compelling finding of Mycobacterium avium paratuberculosis (MAP) circulating disproportionately within the bloodstream of type 1 diabetics was subsequently confirmed by culturing it straight out of their blood. MAP infection and type 1 diabetes appear to go together, but we didn’t know which came first. Does the infection make kids more susceptible to diabetes? Might …

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Solriamfetol for Excessive Sleepiness in Narcolepsy and Obstructive Sleep Apnea

Annals of Pharmacotherapy, Ahead of Print. Objective: The purpose of this article is to review the available clinical trial data that led to the Food and Drug Administration (FDA) approval of solriamfetol as well as its role in clinical practice. Data Sources: A MEDLINE/PubMed search was conducted (January 2000 to February 2020) using the keyword …

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Solriamfetol for Excessive Sleepiness in Narcolepsy and Obstructive Sleep Apnea

Annals of Pharmacotherapy, Ahead of Print. Objective: The purpose of this article is to review the available clinical trial data that led to the Food and Drug Administration (FDA) approval of solriamfetol as well as its role in clinical practice. Data Sources: A MEDLINE/PubMed search was conducted (January 2000 to February 2020) using the keyword …

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Solriamfetol for Excessive Sleepiness in Narcolepsy and Obstructive Sleep Apnea

Annals of Pharmacotherapy, Volume 54, Issue 10, Page 1016-1020, October 2020. Objective:The purpose of this article is to review the available clinical trial data that led to the Food and Drug Administration (FDA) approval of solriamfetol as well as its role in clinical practice.Data Sources:A MEDLINE/PubMed search was conducted (January 2000 to February 2020) using …

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Telemedicine & Telehealth Emerge as Medical Marketing Opportunities During COVID

March 17, 2020, may well be remembered as the day the telemedicine revolution finally took off. Telemedicine and Telehealth‘s adoption, fast-tracked by Coronavirus/COVID, will create profound changes in how healthcare services are provided — while also spawning new healthcare marketing opportunities. Telemedicine & Telehealth: Innovation & Opportunities Earlier last month, in the interest of public safety, …

Telemedicine & Telehealth Emerge as Medical Marketing Opportunities During COVID

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Good Beginners Book on HTAs?

Hello, I’m based in UK and I just finished my masters in Pharmaceuticals but we didn’t really go over market access, pricing, reimbursement, and HTAs which I am interested in. Does anyone know any good books, preferably an e-book as I cant visit the library for obvious reasons! Just in case, for anyone who doesn’t …

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LIGHT OF HOPE FOR STUDENTS AFTER PHARMA, BIOTECH, HEALTHCARE & LIFE SCIENCES DEGREES

Students opt for Pharma, Healthcare, Nutrition, and Food Industries when they are interested to become either a part of medicine and food research respectively apart from being a doctor. However, after the completion of such degrees, many students like you, struggled to choose their career as most fresh passouts are not aware about all the …

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What is Coronavirus ? Coronavirus Symptoms and Prevention

What is Coronavirus ?, Coronavirus Symptoms and Prevention Understanding the Novel Coronavirus (2019-nCoV) What is Coronavirus According to the World Health Organization[i], Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). …

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The future of health didn’t seem so far away at TEDMED 2020

By Neal Batra, principal and Kulleni Gebreyes, M.D., principal, Deloitte Consulting LLP Last month, we led a discussion about the future of health at TEDMED 2020 in Boston (turns out this was the last in-person meeting any of us will attend for a while). We explained that we believe over the next 20 years, consumers—rather …

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The Role of Meat and Dairy in Triggering Type 1 Diabetes

Type 1 diabetes “arises following the autoimmune destruction of the insulin-producing pancreatic β [beta] cells…[and] is most often diagnosed in children and adolescents, usually presenting with a classic trio of symptoms” as their blood sugars spike: excessive thirst, hunger, and urination. They need to go on insulin for the rest of their lives, since their …

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Stigma – the other enemy people face in the battle against COVID-19

ABOUT AUTHOR Dr. Sheenu Jain Associate Professor IIHMR University, Jaipur World is anxiously waiting to see The-end of Corona virus; we are struggling to regain the sense of control we lost to this threat.  COVID-19 will be remembered as a disease that divided us and affecting us much harder than we imagined.

COVID Healthcare Marketing Questions: Pause, Pivot, or Push Forward

COVID Healthcare Marketing Webinar COVID-19 has changed the healthcare industry quicker in the last two weeks than in the last 50 years. With medical practices temporarily shutting down and elective procedures put on hold, what should healthcare networks and healthcare specialists do with their marketing campaigns‘ strategies? Stewart Gandolf, CEO, Healthcare Success Aaron Clifford, SVP …

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Moving remote: the post-pandemic clinical trial

The restrictions on movement and normal interaction owing to COVID-19 pose a distinct challenge to the traditional clinical trial model, as patients, investigators and clinical staff are either confined to their homes or seeking to avoid healthcare settings.    Those running clinical trials over the past weeks have had to adapt rapidly by fast-tracking digital …

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How to Treat Endometriosis with Diet

“Endometriosis is a major cause of disability and compromised quality of life in women and teenage girls.” It “is a chronic disease which is under-diagnosed, under-reported, and under-researched…[and for patients, it] can be a nightmare of misinformation, myths, taboos, lack of diagnosis, and problematic hit-and-miss treatments overlaid by a painful, chronic, stubborn disease.” Pain is …

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Research Headlines – Collecting the world’s viruses, empowering urgent research

Ebola, Zika, MERS, COVID-19? An EU-funded collection of mammalian viruses is supporting researchers around the globe in their efforts to shed new light on old and emerging illnesses and advance their treatment and control. This Research Infrastructure is the world’s largest archive of such pathogens and is set up to respond to outbreaks quickly.

Research Headlines – Collecting the world’s viruses, empowering urgent research

Ebola, Zika, MERS, COVID-19? An EU-funded collection of mammalian viruses is supporting researchers around the globe in their efforts to shed new light on old and emerging illnesses and advance their treatment and control. This Research Infrastructure is the world’s largest archive of such pathogens and is set up to respond to outbreaks quickly.

Research Headlines – Collecting the world’s viruses, empowering urgent research

Ebola, Zika, MERS, COVID-19? An EU-funded collection of mammalian viruses is supporting researchers around the globe in their efforts to shed new light on old and emerging illnesses and advance their treatment and control. This Research Infrastructure is the world’s largest archive of such pathogens and is set up to respond to outbreaks quickly.

How should pharma approach patient collaboration in the 2020s?

From the growing range of patient entities through to new possibilities stemming from technology and patient-generated data, pharma has more and more ways to innovate when it comes to collaborating with patients. 
   Now pharma needs to identify the ones that will really move the dial. “Clearly there is a shift from patient engagement …

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Leading the hunt for a COVID-19 vaccine

  Paul Stoffels, J&J’s Chief Scientific Officer, has given delegates at eyeforpharma’s Barcelona Virtual conference exclusive insights into its rapid progress in the search for a vaccine to the COVID-19 virus.   Speaking to Reuters News on day two of the five-day conference, Stoffels said J&J’s potential vaccine, which has just been chosen as a …

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What to Eat and Avoid for Women with BRCA Gene Mutations

Five studies have been performed on breast cancer survival and soy foods involving more than 10,000 breast cancer patients, and together they found that those who eat more soy live longer and have a lower risk of the cancer coming back. What about women who carry breast cancer genes? Fewer than 10 percent of breast …

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Patients and RWE: Is this the year?

The long-hyped redefinition of healthcare through wearable tech has been… well, long hyped. Early projects, such as Apple HealthKit and Fitbit, were undoubtably important in redefining ‘the possible’ but they haven’t yet achieved transformative application.    Much has been written on why the philosophy that has driven the astonishing success of consumer technology doesn’t translate …

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A Renewed Commitment to Our Nation’s Older Adults

The law reauthorizes critical Older Americans Act (OAA) programs through 2024. Since 1965, the OAA has provided critical services that have enabled millions of older Americans to stay in their own homes and communities.  Services supported by the OAA include congregate and home-delivered meals, case management, specialized transportation services, employment and volunteer programs, adult day …

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10 ways to avoid corona – Corona Virus Tips

10 ways to avoid corona – Corona Virus Tips: Countries around the world are monitoring the outbreak of Coronovirus Disease 2019 (COVID-19) and are suggesting ways to avoid it. Several things are being told to flow from the corona, which can prevent it from spreading.Today we are telling you about the same coronavirus tips. Carefully …

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Onasemnogene Abeparvovec-xioi: Gene Therapy for Spinal Muscular Atrophy

Annals of Pharmacotherapy, Volume 54, Issue 10, Page 1001-1009, October 2020. Objective:To review the efficacy and safety of onasemnogene abeparvovec-xioi (Zolgensma) in the treatment of spinal muscular atrophy (SMA).Data Sources:An English-language literature search of PubMed, MEDLINE, and Ovid (1946 to December 2019) was completed using the terms onasemnogene, AVXS-101, and spinal muscular atrophy. Manufacturer prescribing …

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Onasemnogene Abeparvovec-xioi: Gene Therapy for Spinal Muscular Atrophy

Annals of Pharmacotherapy, Ahead of Print. Objective: To review the efficacy and safety of onasemnogene abeparvovec-xioi (Zolgensma) in the treatment of spinal muscular atrophy (SMA). Data Sources: An English-language literature search of PubMed, MEDLINE, and Ovid (1946 to December 2019) was completed using the terms onasemnogene, AVXS-101, and spinal muscular atrophy. Manufacturer prescribing information, article …

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Onasemnogene Abeparvovec-xioi: Gene Therapy for Spinal Muscular Atrophy

Annals of Pharmacotherapy, Ahead of Print. Objective: To review the efficacy and safety of onasemnogene abeparvovec-xioi (Zolgensma) in the treatment of spinal muscular atrophy (SMA). Data Sources: An English-language literature search of PubMed, MEDLINE, and Ovid (1946 to December 2019) was completed using the terms onasemnogene, AVXS-101, and spinal muscular atrophy. Manufacturer prescribing information, article …

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Coronavirus: 5 Ways You Can Use Social Media and Digital Marketing to Help the Public During the COVID-19 Pandemic

Today I am going to share some important ways that doctors, hospitals and healthcare marketers can use social media to inform the public during the COVID-19 crisis. Priority One: Use social media to convince people to comply with social distancing, and consequently help us all, “flatten the curve!” The US Surgeon General, Dr. Jerome Adams, …

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Sourcing investigational COVID-19 drugs

Are you trying to source investigational COVID-19 drugs? We’ve pulled out all the relevant supply-chain resources at https://www.drugpatentwatch.com/covid-19/ . Let me know what more we can do.. edit: updated url submitted by /u/drugpatentwatch [link] [comments]

Q&A with Peter Piot about COVID-19

At TEDMED’s gathering in Boston, we had the opportunity to interview on stage the world’s top virologist, Peter Piot. In plain English, Peter provided solid scientific knowledge about COVID-19 and how to cope with it. Short answers, clear explanations. Based on that live interview here is a written Q & A supporting the responses to …

Q&A with Peter Piot about COVID-19

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Why LTAC Hospitals are often the Right Choice for Critically Ill Patients

<p>Choosing the care path for critically ill patients is essential to achieving optimal outcomes for both patients and providers. For patients, without the right clinical capabilities and surrounding environment in which to recover, they may suffer medical setbacks that impede recovery. For providers, such as hospitals, major penalties (including extensive fines) can be incurred due …

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