Econometrics

Should you adjust for covariates when analyzing data from randomized controlled trials?

FDA draft guidance published this month says you should. In most cases, adjusting for covariates is not necessary. Randomization generally insurers that covariates are balanced across clinical trial arms. Randomization, however, may not always result in perfectly balanced trial arms. In these cases, the FDA… Read More »Should you adjust for covariates when analyzing data from randomized controlled trials?

What is immortal time bias?

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A recent JAMA paper by Yadav and Lewis (2021) provide the answer: Bias from immortal time periods is the error in estimating the association between the exposure and the outcome that results from misclassification or exclusion of time intervals Yadav and Lewis (2021) Sounds simple… Read More »What is immortal time bias?

What about a cure model?

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That is the title of a helpful video from Nicholas Lattimer of University of Sheffield. You can view all his videos here.