COVID-19

Amnesty says COVID jab producers are causing human rights crisis

Amnesty International has slammed the six pharma companies behind the bulk of COVID-19 vaccine supplies of for not agreeing to waive their intellectual property rights and share the technology behind them. The charity says AstraZeneca, BioNTech, Johnson & Johnson, Moderna, Novavax, and Pfizer are fuelling an “unprecedented human rights crisis” as a result and their …

Amnesty says COVID jab producers are causing human rights crisis Read More »

At an Overrun ICU, ‘the Problem Is We Are Running Out of Hallways’

BILLINGS, Mont. — Nurses fill the hospital room to turn a patient from his stomach to his back. The ventilator forcing air into him is most effective when he’s on his stomach, so he is in that position most hours of the day, sedated and paralyzed by drugs. Lying on his stomach all those hours …

At an Overrun ICU, ‘the Problem Is We Are Running Out of Hallways’ Read More »

Public Health Experts ‘Flabbergasted’ That Biden Still Hasn’t Picked an FDA Chief

President Joe Biden’s failure to name someone to lead the Food and Drug Administration, more than 10 months after the election, has flummoxed public health experts who say it’s baffling for the agency to be without a permanent leader during a national health crisis. The pandemic has taxed the FDA, an 18,000-person agency whose chiefs …

Public Health Experts ‘Flabbergasted’ That Biden Still Hasn’t Picked an FDA Chief Read More »

Will ‘Dr. Disinformation’ Ever Face the Music?

Earlier this month, Dr. Rashid Buttar posted on Twitter that covid-19 “was a planned operation” and shared an article alleging that most people who got the covid vaccine would be dead by 2025. His statement is a recent example in what has been a steady stream of spurious claims surrounding the covid vaccines and treatments …

Will ‘Dr. Disinformation’ Ever Face the Music? Read More »

RwHealth, the Artificial Intelligence provider for the NHS, promises to transform healthcare

RwHealth, the leading provider of Artificial Intelligence to the healthcare industry, has today reported 160 per cent year-on-year growth as its data-led solutions are increasingly embraced by NHS trusts, private healthcare providers and major pharmaceutical companies.   RwHealth’s unique Data Science Platform combines Artificial Intelligence (AI), Machine Learning and Data Science to give healthcare providers …

RwHealth, the Artificial Intelligence provider for the NHS, promises to transform healthcare Read More »

Pfizer, BioNTech prep low-dose COVID jab filing for kids aged 5 to 11

With positive phase 2/3 results for their COVID-19 vaccine Comirnaty in hand for the five to 11 age group, Pfizer and BioNTech are planning to move swiftly ahead with a filing for emergency use that could be approved in a matter of weeks. The data is the first generated with any COVID-19 vaccine in this …

Pfizer, BioNTech prep low-dose COVID jab filing for kids aged 5 to 11 Read More »

Pfizer, BioNTech prep low-dose COVID jab filing for kids aged 5 to 11

With positive phase 2/3 results for their COVID-19 vaccine Comirnaty in hand for the five to 11 age group, Pfizer and BioNTech are planning to move swiftly ahead with a filing for emergency use that could be approved in a matter of weeks. The data is the first generated with any COVID-19 vaccine in this …

Pfizer, BioNTech prep low-dose COVID jab filing for kids aged 5 to 11 Read More »

Patient Self-Scheduling as a Competitive Advantage – Interview with the Expert

The rising popularity of virtual care seems to be extending itself into other areas of patient experience, including a re-energized consumer preference for digital self-scheduling. In fact, McKinsey & Company reports that telehealth visits and utilization are 38x higher than pre-COVID-19 levels (July 2021). Meanwhile, Experian Health’s State of Patient Access 2.0 survey, released in …

Patient Self-Scheduling as a Competitive Advantage – Interview with the Expert Read More »

La máscara de tela, ¿es suficiente para proteger contra la variante delta?

En los últimos meses, algunas compañías aéreas europeas han prohibido el uso de máscaras de tela para controlar la propagación del coronavirus durante los vuelos, en favor de las quirúrgicas y los respiradores N95.       Se trata de un nuevo debate sobre la eficacia del popular cubrebocas de tela, cuyo uso se extendió desde los …

La máscara de tela, ¿es suficiente para proteger contra la variante delta? Read More »

Pfizer reports positive Covid-19 vaccine data in kids; FDA is filing coming

A lower-dose version of Pfizer and BioNTech’s Covid-19 vaccine showed safety and efficacy results in children 5 to 11 that were comparable to those in an older age group. With these preliminary data, the companies said they plan to seek emergency use authorization of the shots.

I Got a ‘Mild’ Breakthrough Case. Here’s What I Wish I’d Known.

The test results that hot day in early August shouldn’t have surprised me — all the symptoms were there. A few days earlier, fatigue had enveloped me like a weighted blanket. I chalked it up to my weekend of travel. Next, a headache clamped down on the back of my skull. Then my eyeballs started …

I Got a ‘Mild’ Breakthrough Case. Here’s What I Wish I’d Known. Read More »

Ask KHN-PolitiFact: Is My Cloth Mask Good Enough to Face the Delta Variant?

In recent months, some European airlines have banned the use of cloth face coverings to control the spread of the coronavirus during air travel, instead favoring surgical masks — sometimes referred to as medical or disposable — and N95 respirators. It’s another salvo in the debate over the effectiveness of the ubiquitous cloth mask, which …

Ask KHN-PolitiFact: Is My Cloth Mask Good Enough to Face the Delta Variant? Read More »

FDA panel backs booster shots in high-risk groups after rejecting broader proposal

An FDA advisory panel voted down a proposal for booster shots of the Pfizer/BioNTech Covid-19 in the general population, opting instead to support third shots in certain high-risk groups, such as the elderly. Panelists want to see more information supporting the need for a booster, as well as data about a heart safety risk the …

FDA panel backs booster shots in high-risk groups after rejecting broader proposal Read More »

Covid-Overwhelmed Hospitals Postpone Cancer Care and Other Treatment

It’s a bad time to get sick in Oregon. That’s the message from some doctors, as hospitals fill up with covid-19 patients and other medical conditions go untreated. Charlie Callagan looked perfectly healthy sitting outside recently on his deck in the smoky summer air in the small Rogue Valley town of Merlin, in southern Oregon. …

Covid-Overwhelmed Hospitals Postpone Cancer Care and Other Treatment Read More »

Scientists Examine Kids’ Unique Immune Systems as More Fall Victim to Covid

Eighteen months into the covid-19 pandemic, with the delta variant fueling a massive resurgence of disease, many hospitals are hitting a heartbreaking new low. They’re now losing babies to the coronavirus. The first reported covid-related death of a newborn occurred in Orange County, Florida, and an infant has died in Mississippi. Merced County in California …

Scientists Examine Kids’ Unique Immune Systems as More Fall Victim to Covid Read More »

KHN’s ‘What the Health?’: Much Ado About Drug Prices

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. Congressional Democrats are finding it harder to actually write legislation to lower drug prices than it is to make promises about it. But the drug price provisions of the $3.5 trillion social-spending bill …

KHN’s ‘What the Health?’: Much Ado About Drug Prices Read More »

Ahead of FDA adcomm, Pfizer, Moderna say COVID jab efficacy dips

Pfizer and Moderna have both reported data that they say backs up the need for booster shots of their COVID-19 vaccines ahead of an FDA advisory committee meeting tomorrow, although the regulator seems less convinced. Documents published ahead of the panel by the FDA reviewers suggest that there is some evidence from observational studies that …

Ahead of FDA adcomm, Pfizer, Moderna say COVID jab efficacy dips Read More »

When Covid Deaths Are Dismissed or Stigmatized, Grief Is Mixed With Shame and Anger

[Editor’s note: This story contains language references that some readers may find offensive.] Months after Kyle Dixon died, his old house in Lanse, Pennsylvania, is full of reminders of a life cut short. His tent and hiking boots sit on the porch where he last put them. The grass he used to mow has grown …

When Covid Deaths Are Dismissed or Stigmatized, Grief Is Mixed With Shame and Anger Read More »

How Fauci and the NIH Got Ahead of the FDA and CDC in Backing Boosters

In January — long before the first jabs of covid-19 vaccine were even available to most Americans — scientists working under Dr. Anthony Fauci at the National Institute of Allergy and Infectious Diseases were already thinking about potential booster shots. A month later, they organized an international group of epidemiologists, virologists and biostatisticians to track …

How Fauci and the NIH Got Ahead of the FDA and CDC in Backing Boosters Read More »

Complexities of COVID-19 manufacturing

Getting from a mRNA COVID-19 vaccine to scaling to manufacture these vaccines for billions of people is far from simple: Manufacturing mRNA vaccines for the first time in a very short timeframe required significant innovation and remains a technically challenging endeavor. The process proved to be technically challenging as Pfizer developed a 50,000 step process. …

Complexities of COVID-19 manufacturing Read More »

Analysis: Cost of care for unvaccinated Covid patients spikes to $5.7B

The cost of hospital care for unvaccinated Covid-19 patients has more than doubled, jumping from about $2 billion to $5.7 billion over the summer. And this figure may still be lower than the actual cost burden unvaccinated people represent to the healthcare system.

Opioid use for pain relief increased as a result of the Covid-19 pandemic

The use of opioids for pain relief in patients awaiting hip and knee replacement surgery increased dramatically during the pandemic according to new research from the University of Aberdeen. Published in the BMJ Quality & Safety, the study found that the numbers of patients using opioids while waiting for surgery increased by 40% compared to pre-pandemic levels.   Opioids such as morphine and tramadol are …

Opioid use for pain relief increased as a result of the Covid-19 pandemic Read More »

Más de la mitad de los estados han revertido poderes de salud pública durante la pandemia

Motivados por votantes enojados por los cierres y los mandatos sobre el uso de máscaras durante la pandemia, legisladores republicanos en más de la mitad de los estados de EE.UU. están quitando los poderes que los funcionarios estatales y locales usan para proteger al público contra las enfermedades infecciosas. Una revisión de KHN encontró que, …

Más de la mitad de los estados han revertido poderes de salud pública durante la pandemia Read More »

EU ‘negotiating with Valneva’ over COVID-19 vaccine contract

The European Commission is reportedly in advanced discussions with French biotech Valneva about picking up the contract to supply COVID-19 vaccines that was terminated by the UK government this week. A French government source told Reuters that the EU is considering using the VLA2001 vaccine as part of its booster campaign plans, along with a …

EU ‘negotiating with Valneva’ over COVID-19 vaccine contract Read More »

Biden Releases a New Plan to Combat Covid, but Experts Say There’s Still a Ways to Go

Promise: “I’m never going to raise the white flag and surrender. We’re going to beat this virus. We’re going to get it under control, I promise you. “ On the campaign trail last year, Joe Biden promised that, if elected president, he would get covid-19 under control. Since assuming office in January, Biden has continued …

Biden Releases a New Plan to Combat Covid, but Experts Say There’s Still a Ways to Go Read More »

Over Half of States Have Rolled Back Public Health Powers in Pandemic

Republican legislators in more than half of U.S. states, spurred on by voters angry about lockdowns and mask mandates, are taking away the powers state and local officials use to protect the public against infectious diseases. A KHN review of hundreds of pieces of legislation found that, in all 50 states, legislators have proposed bills …

Over Half of States Have Rolled Back Public Health Powers in Pandemic Read More »

RedHill’s Opaganib (ABC294640) Fails to Meet its Primary Endpoints in P-II/III Study for the Treatment of Severe COVID-19

Shots: The P-II/III study evaluates opaganib +SoC vs PBO + SoC in a ratio (1:1) in 475 patients with COVID-19 pneumonia requiring hospitalization & treatment with supplemental oxygen The preliminary data showed that the study did not meet its 1EPs while efficacy EPs showed consistent trends. The therapy demonstrated good tolerability with balanced AEs & …

RedHill’s Opaganib (ABC294640) Fails to Meet its Primary Endpoints in P-II/III Study for the Treatment of Severe COVID-19 Read More »

The tech revolution reshaping European healthcare

The European health tech industry has made a “quantum leap” into using digital health technology due to the pandemic with the help of a growing number of trailblazing entrepreneurs, according to AlbionVC. The London-based venture capital firm provides a useful overview of how healthcare has changed over the last decade, and where digital health is …

The tech revolution reshaping European healthcare Read More »

Everest Signs a License Agreement with Providence to Advance mRNA Vaccines

Shots: Providence to receive $100M up front for Providence’s PTX-COVID19-B, mRNA technology & other products, ~$300M upon achievement of milestones, $100M in profit-sharing along with royalties in Greater China & Singapore. Providence is also eligible to receive royalties based on vaccine sales in Everest Territories Everest gains rights to Providence’s PTX-COVID19-B in Greater China, Asia, …

Everest Signs a License Agreement with Providence to Advance mRNA Vaccines Read More »

UK poised to announce booster COVID jabs for over-50s

The UK government is due to announce a large-scale booster vaccine campaign against COVID-19 for all adults aged 50 and over later today, adding to its plan for third doses for people with weakened immune systems. The plan will see millions of doses of the Pfizer/BioNTech mRNA vaccine administered across the autumn and winter to …

UK poised to announce booster COVID jabs for over-50s Read More »

ICUs Are Filled With Covid — And Regret

It’s a struggle for Joe Gammon to talk. Lying in his bed in the intensive care unit at Ascension Saint Thomas Hospital in Nashville, Tennessee, this month, he described himself as “naive.”  “If I would have known six months ago that this could be possible, this would have been a no-brainer,” said the 45-year-old father of …

ICUs Are Filled With Covid — And Regret Read More »

How 24/7 self-scheduling can improve the post-pandemic patient experience

This is the second in a series of blog posts that will highlight how the patient journey has evolved since the onset of COVID-19. This series will take you through the changes that impacted every step of the patient journey and provide strategic recommendations to move forward. In this post, we explore how 24/7 self-scheduling can …

How 24/7 self-scheduling can improve the post-pandemic patient experience Read More »

Sepsis Opportunities: Lessons from the COVID-19 Pandemic

Sepsis is the body’s extreme response to an infection. It is a life-threatening medical emergency. Sepsis happens when an infection you already have triggers a chain reaction throughout your body. Infections that lead to sepsis most often start in the lung, urinary tract, skin, or gastrointestinal tract. Without timely treatment, sepsis can rapidly lead to …

Sepsis Opportunities: Lessons from the COVID-19 Pandemic Read More »

Valneva slumps as UK dumps €1.4bn order for COVID-19 jab

The UK has terminated its order for up to 190 million doses of a COVID-19 vaccine developed by French biotech company Valneva, accusing it of breaching their supply agreement. Valneva said it “strenuously denies” that allegation, but added that the €1.4 billion ($1.65 billion) contract does provide the UK government with the right to exit …

Valneva slumps as UK dumps €1.4bn order for COVID-19 jab Read More »

Why At-Home Rapid Covid Tests Cost So Much, Even After Biden’s Push for Lower Prices

Rapid at-home covid tests are flying off store shelves across the nation and are largely sold out online as the delta variant complicates a return to school, work and travel routines. But at $10 or $15 a test, the price is still far too high for regular use by anyone but the wealthy. A family …

Why At-Home Rapid Covid Tests Cost So Much, Even After Biden’s Push for Lower Prices Read More »

FDA sets expectations for pediatric Covid-19 vaccines; decision could come mid-fall

Acknowledging the demand for a Covid-19 vaccine for children, the FDA said it expects regulatory review could take weeks, not months, depending on the timing of a submission from vaccine developers. U.S. health officials told Reuters they expect the Pfizer/BioNTech vaccine will be the first one ready for an FDA submission.

Journalists Explain Ramifications of Theranos Trial and Texas’ New Abortion Law

KHN Editor-in-Chief Elisabeth Rosenthal discussed health tech and the start of the fraud trial of Elizabeth Holmes, who founded the biological screening company Theranos, on WGN’s “The John Williams Show” on Wednesday. Click here to hear Rosenthal on “The John Williams Show” KHN senior correspondent Julie Appleby discussed abortion law in Texas, covid-19 and vaccination …

Journalists Explain Ramifications of Theranos Trial and Texas’ New Abortion Law Read More »

ECMO Life Support Is a Last Resort for Covid, and in Short Supply in South

Hospital discharge day for Phoua Yang was more like a pep rally. On her way rolling out of TriStar Centennial Medical Center in Nashville, Tennessee, she teared up as streamers and confetti rained down on her. Nurses chanted her name as they wheeled her out of the hospital for the first time since she arrived …

ECMO Life Support Is a Last Resort for Covid, and in Short Supply in South Read More »

It’s Not Just Covid: Recall Candidates Represent Markedly Different Choices on Health Care

SACRAMENTO, Calif. — Gov. Gavin Newsom’s covid-19 rules have been a lightning rod in California’s recall election. But there’s a lot more at stake for Californians’ health care than mask and vaccine mandates. Newsom, a first-term Democrat, argues that their fundamental ability to get health insurance and medical treatments is on the line. Republicans are …

It’s Not Just Covid: Recall Candidates Represent Markedly Different Choices on Health Care Read More »

MHRA clears third doses of AZ, Pfizer COVID jabs

The UK medicines regulator has cleared the use of a third dose of both the AstraZeneca and Pfizer COVID-19 vaccines, in readiness for a possible booster campaign ahead of the winter months. The decision means there is now no impediment to starting a booster drive – assuming the Joint Committee on Vaccination and Immunisation (JCVI) …

MHRA clears third doses of AZ, Pfizer COVID jabs Read More »

Las exenciones “religiosas” agregan más complicación a los mandatos de vacunación que se avecinan

En el norte de California, el pastor de una mega iglesia reparte formularios de exención religiosa a sus feligreses. Un senador estatal de Nuevo México ayudará con este documento, apuntando al uso de células fetales en el desarrollo de algunas vacunas, décadas atrás. Y un evangelista con sede en Texas ofrece cartas de exención a …

Las exenciones “religiosas” agregan más complicación a los mandatos de vacunación que se avecinan Read More »

KHN’s ‘What the Health?’: The Future of Public Health

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. Click here for a transcript of the episode. The covid-19 pandemic has shone a spotlight on public health, a key part of the health care system that …

KHN’s ‘What the Health?’: The Future of Public Health Read More »

‘Religious’ Exemptions Add Legal Thorns to Looming Vaccine Mandates

In Northern California, the pastor of a megachurch hands out religious exemption forms to the faithful. A New Mexico state senator will “help you articulate a religious exemption” by pointing to the decades-old use of aborted fetal cells in the development of some vaccines. And a Texas-based evangelist offers exemption letters to anyone — for …

‘Religious’ Exemptions Add Legal Thorns to Looming Vaccine Mandates Read More »

Even in Red States, Colleges Gravitate to Requiring Vaccines and Masks

As students head to college this fall, hundreds of schools are requiring employees and students to be vaccinated against covid, wear masks on campus or both. But at some schools, partisan politics have bolstered efforts to stymie public health protections. Events at the University of South Carolina, in a deeply conservative state, demonstrate the limits …

Even in Red States, Colleges Gravitate to Requiring Vaccines and Masks Read More »

Preparing for a post-pandemic world

Janssen’s Mark Hicken, VP of strategy, EMEA, looks at what COVID-19 has taught us and how we can become stronger as we emerge from the pandemic. There’s plenty of talk about a post-COVID world right now, which can seem strange when so many places are still feeling the impact or remain in the grip of …

Preparing for a post-pandemic world Read More »

Gates Foundation ramps up funding to Exscientia in COVID project

The Bill & Melinda Gates Foundation must have liked what it saw in an initial collaboration with Exscientia to find new antivirals for COVID-19 and related diseases. Two months after providing initial funding of $1.5 million to get the ball rolling, the philanthropic organisation has now pledged $35 million in funding to a four-year project …

Gates Foundation ramps up funding to Exscientia in COVID project Read More »

AZ CEO Soriot urges caution on COVID booster doses

The UK should think twice before backing widespread use of COVID-19 booster vaccinations, as to do so could place unnecessary burden on the NHS over the winter, according to AstraZeneca chief executive Pascal Soriot. In a letter to The Daily Telegraph newspaper with AZ’s head of biopharma R&D Mene Pangalos, Soriot write that the UK …

AZ CEO Soriot urges caution on COVID booster doses Read More »

Listen: Many Schools Are Buying High-Tech Air Purifiers. What Should Parents Know?

This is a collaboration between KHN and “Science Friday.” Listen to the conversation between KHN senior correspondent Christina Jewett and Science Friday’s host and executive producer, Ira Flatow. As students return to school, parents are getting a lot of mail about what schools are doing to better protect kids in the classroom — including details …

Listen: Many Schools Are Buying High-Tech Air Purifiers. What Should Parents Know? Read More »

As Delta surges, CMIOs’ focus on plans to provide vaccine booster shots, fight false information

Chief medical information officers are in a unique position to help their organizations fight the Covid-19 pandemic — from setting up IT systems to support Covid testing, care and vaccination to helping fight fast-spreading misinformation.

UK pledges £5.4bn to NHS to ease COVID-19 treatment backlog

NHS England will get an extra £5.4 billion ($7.5 billion) in funding over the next six months to respond to COVID-19 and address a backlog in care caused by the pandemic, according to the UK government. The total includes £1 billion to get delivery of routine surgeries and treatments to patients delayed by COVID-19 back …

UK pledges £5.4bn to NHS to ease COVID-19 treatment backlog Read More »

EMA looks at booster data for Pfizer/BioNTech COVID-19 jab

The EU regulator has started to review a marketing application filed by Pfizer and BioNTech for a third, booster dose of their Comirnaty COVID-19 vaccine given six months after the first course to people aged 16 and over. The EMA’s CHMP human medicines committee will carry out an accelerated review of the application, which comes …

EMA looks at booster data for Pfizer/BioNTech COVID-19 jab Read More »

V-Safe: How Everyday People Help the CDC Track Covid Vaccine Safety With Their Phones

Of the 203 million people who have received at least one dose of a covid-19 vaccine, more than 9 million have enrolled in a program to share information about their health since getting the shot. The initiative was created for the covid-19 vaccines to complement the Centers for Disease Control and Prevention’s vaccine safety monitoring …

V-Safe: How Everyday People Help the CDC Track Covid Vaccine Safety With Their Phones Read More »

The Pandemic Almost Killed Allie. Her Community’s Vaccination Rate Is 45%.

The Allie Henderson who stepped out of her mother’s car to a driveway full of cheering friends and family holding “Welcome Home” signs was a wisp of her former self. After 10 days in the hospital with a near-fatal case of covid inflammatory syndrome, the then-13-year-old softball phenom and beloved, straight-A student was lethargic and …

The Pandemic Almost Killed Allie. Her Community’s Vaccination Rate Is 45%. Read More »

Moderna’s Spikevax Receives TGA’s Provisional Approval to Treat COVID-19 in Patients Aged 12-17 Years

Shots: TGA has provisionally approved the use of Moderna’s Spikevax (elasomeran) in individuals aged ≥12yrs. The decision follows the provisional approval granted by the TGA to Spikevax on Aug 09, 2021 for use in individuals aged ≥18yrs. Provisional approval for this group follows the data supporting the efficacy & safety of the vaccine. The recommended …

Moderna’s Spikevax Receives TGA’s Provisional Approval to Treat COVID-19 in Patients Aged 12-17 Years Read More »

Does Our Healthcare System Work for the Most Vulnerable Americans?

By DEBORAH AFEZOLLI, CARL-PHILIPPE ROUSSEAU, HELEN FERNANDEZ, ELIZABETH LINDENBERGER “Why did you choose this field?” Most physicians are asked this question at some point in their early careers. We are geriatrics and palliative medicine physicians, so when that question is posed to us, it is invariably followed by another: “Isn’t your job depressing?” No, our …

Does Our Healthcare System Work for the Most Vulnerable Americans? Read More »

Covid, delta y tu deporte favorito, ¿es seguro ir a un estadio?

La temporada de fútbol americano universitario está precalentando, la de la Liga Nacional de Fútbol Americano comienza el 9 de septiembre. Béisbol, fútbol, basketball. Por primera vez desde 2019, casi todos los estadios y canchas estarán completamente abiertos para los fanáticos. Antes de la era COVID, sentarse hombro con hombro en un estadio con decenas …

Covid, delta y tu deporte favorito, ¿es seguro ir a un estadio? Read More »

Survey: 40% of health systems ramping up hiring efforts amid workforce shortage

A majority of organizations (93%) said they are focused on both attracting and retaining top talent, a new survey from Aon shows. They are offering various benefits to do so, including onsite or near-site health clinics for employees.

Targeting COVID-19 and cancer with immunotherapy advancements

Anna Biosciences’ Dr Anthony Rullo discusses the drug development company’s immunotherapy platform. Over the last 30 years, we have seen dramatic improvements in patient outcomes due to the emergence of biologics – particularly monoclonal antibodies – as therapies for a wide variety of diseases and infections. Monoclonal antibodies (mABs) are highly specific therapies associated with …

Targeting COVID-19 and cancer with immunotherapy advancements Read More »

FDA schedules adcomm for Pfizer’s COVID booster filing

The FDA has said it will hold an advisory committee meeting later this month to discuss Pfizer and BioNTech’s filing for approval of a third booster dose of their COVID-19 vaccine Comirnaty in people aged 16 and over. The adcomm is scheduled for 17 September and will discuss the Pfizer/BioNTech filing as well as booster …

FDA schedules adcomm for Pfizer’s COVID booster filing Read More »

Italian ‘chatbot’ predicted COVID-19 spikes, says study

An online tool used by people in Italy to manage their potential exposure to COVID-19 using a simple chat interface has shown that it can spot emerging trends days ahead of the national surveillance system. The decision support system (DSS) – developed by Italian digital health startup Paginemediche – provided a way for people to …

Italian ‘chatbot’ predicted COVID-19 spikes, says study Read More »

Minister for Seniors at Famed Church Confronts Ageism and the Shame It Brings

Later life is a time of reassessment and reflection. What sense do we make of the lives we have lived? How do we come to terms with illness and death? What do we want to give to others as we grow older? Lynn Casteel Harper, 41, has thought deeply about these and other spiritual questions. …

Minister for Seniors at Famed Church Confronts Ageism and the Shame It Brings Read More »

Voters in Tight Recall Race Sound Off on California Gov. Newsom’s Covid Leadership

Gov. Gavin Newsom’s first term in office has been defined by his response to the covid-19 pandemic, which has claimed the lives of more than 65,400 Californians. The Democratic governor issued the first statewide stay-at-home order in the nation, and his policies kept most public school students at home last year. But his own children …

Voters in Tight Recall Race Sound Off on California Gov. Newsom’s Covid Leadership Read More »

Merck and Ridgeback Initiate P-III MOVe-AHEAD Study of Molnupiravir for the Prevention of COVID-19 Infection

Shots: The company initiates a P-III MOVe-AHEAD trial to evaluate molnupiravir (800 mg, q12h for 5 days) vs PBO in ~1,332 participants aged 18yrs. who reside in the same household as someone with laboratory-confirmed SARS-CoV-2 infection with symptoms. The trial is being conducted globally The 1EPs of trial i.e., proportion of participants with COVID-19 (laboratory-confirmed) …

Merck and Ridgeback Initiate P-III MOVe-AHEAD Study of Molnupiravir for the Prevention of COVID-19 Infection Read More »

How pharma can help the post-COVID recovery of European cancer care

The new Cancer Care in Europe: Recovering from COVID-19 Disruption white paper assesses the disruption to patient care and the changes physicians implemented during the acute phase of the pandemic, with a focus on the way in which treatment strategies were altered. The publication, which has been supported by Accord Healthcare, also provides a series of …

How pharma can help the post-COVID recovery of European cancer care Read More »

To Quarantine or Not: The Hard Choices Schools Are Leaving to Parents and Staff

On the second day of high school in Texas, Natosha Daniels’ 14-year-old daughter went all day without eating because she did not want to remove her mask. The teen’s school has a couple of thousand students, and the cafeteria was crowded. Plus Round Rock Independent School District outside Austin didn’t require masks, so some students …

To Quarantine or Not: The Hard Choices Schools Are Leaving to Parents and Staff Read More »

NFL Rosters and COVID-19 Vaccination Status

Today teams in the National Football League (NFL) made their final roster cuts. In most years, your ability to make the final roster of an NFL team is dependent on one factor: how well can you play football. This year, however, some teams used additional criteria to determine whether a player made the team. ESPN …

NFL Rosters and COVID-19 Vaccination Status Read More »

Ascendis’s SKYTROFA; MicroTransponder’s VNS System (Vivistim); BioMarin’s Voxzogo; Zimmer-Canary’s Smart Knee Implant; COVID-19 impact on Solid Organ Transplants

FDA’s Green Flag to Ascendis’s Once-Weekly SKYTROFA for Treatment of Pediatric Growth Hormone Deficiency For the treatment of growth failure due to deficiency of growth hormones, the USFDA approved Ascendis Pharma’s Skytrofa (lonapegsomatropin-tcgd) for children of one year and older suffering from an improper secretion of endogenous growth hormone (GH). Growth Hormone Deficiency, commonly known …

Ascendis’s SKYTROFA; MicroTransponder’s VNS System (Vivistim); BioMarin’s Voxzogo; Zimmer-Canary’s Smart Knee Implant; COVID-19 impact on Solid Organ Transplants Read More »

GSK takes SK bio-partnered COVID jab into phase 3

As a top vaccine maker, GlaxoSmithKline has been a laggard in the COVID-19 vaccine race, but has put on a late burst of speed with a start of phase 3 trials of a second candidate that will be compared directly to the AstraZeneca shot. The move follows phase 1/2 results with SK bio’s GBP510, which …

GSK takes SK bio-partnered COVID jab into phase 3 Read More »

Delta Cutting ‘Like a Buzzsaw’ Through Oregon-California Border Counties

If you live in one of the rural communities tucked into the forested hillsides along the Oregon-California border and need serious medical care, you’ll probably wind up at Asante Rogue Regional Medical Center. It serves about nine counties on either side of the border.   It is one of three hospitals Asante owns in the region. …

Delta Cutting ‘Like a Buzzsaw’ Through Oregon-California Border Counties Read More »

Telehealth’s Limits: Battle Over State Lines and Licensing Threatens Patients’ Options

If you live in one state, does it matter that the doctor treating you online is in another? Surprisingly, the answer is yes, and the ability to conduct certain virtual appointments may be nearing an end. Televisits for medical care took off during the worst days of the pandemic, quickly becoming commonplace. Most states and …

Telehealth’s Limits: Battle Over State Lines and Licensing Threatens Patients’ Options Read More »

Lack of a Vaccine Mandate Becomes Competitive Advantage in Hospital Staffing Wars

In the rural northeastern corner of Missouri, Scotland County Hospital has been so low on staff that it sometimes had to turn away patients amid a surge in covid-19 cases. The national covid staffing crunch means CEO Dr. Randy Tobler has hired more travel nurses to fill the gaps. And the prices are steep — …

Lack of a Vaccine Mandate Becomes Competitive Advantage in Hospital Staffing Wars Read More »

Sleepless Nights For Evolutionary Biologists: A Greek Tragedy in The Making

By MIKE MAGEE In my Jesuit high school, we were offered only one science course – chemistry. I took it in my Senior year and did pretty well. In contrast, I took four years of Latin, and three years of Greek, as part of the school’s Greek Honors tract. Little did I know that Covid …

Sleepless Nights For Evolutionary Biologists: A Greek Tragedy in The Making Read More »

Concert Venues Are Banking on Proof of Vaccines or Negative Tests to Woo Back Fans

MARYLAND HEIGHTS, Mo. — Fans of the band Wilco could have reasonably interpreted frontman Jeff Tweedy singing “I Am Trying to Break Your Heart” at an Aug. 13 concert at St. Louis Music Park as the universe explaining the past year or so. For example, 30-year-old fan Lazarus Pittman had planned to see Wilco and …

Concert Venues Are Banking on Proof of Vaccines or Negative Tests to Woo Back Fans Read More »

How COVID-19 changed the patient journey: A call for digital transformation

COVID-19 changed every aspect of the patient journey – placing unprecedented demands on the healthcare system and accelerating the need for digital transformation industry-wide. Telehealth, touchless engagement, and self-service scheduling became the new normal; however, this created new stress on operations, administration, and finance. While this new normal comes with many challenges, data and digital …

How COVID-19 changed the patient journey: A call for digital transformation Read More »

Journalists Give Rundown on Vaccine Mandates and FDA’s Official Approval of the Pfizer Shot

KHN correspondent Rachana Pradhan discussed covid vaccine mandates and the Food and Drug Administration’s recent approval of the Pfizer-BioNTech vaccine on Newsy’s “Morning Rush” on Tuesday. Click here to watch Pradhan on “Morning Rush” KHN Midwest correspondent Cara Anthony talked about covid vaccines on Illinois Public Media’s “The 21st Show” on Monday. Click here to …

Journalists Give Rundown on Vaccine Mandates and FDA’s Official Approval of the Pfizer Shot Read More »

Beneficiarios de Medicaid se vacunan mucho menos contra covid

Los beneficiarios de Medicaid se están vacunando contra covid-19 a tasas mucho más bajas que la población general, mientras los estados buscan las mejores estrategias para mejorar el acceso a las vacunas, y persuadir a quienes siguen indecisos. Los esfuerzos de las agencias estatales de Medicaid y los planes de salud privados que la mayoría …

Beneficiarios de Medicaid se vacunan mucho menos contra covid Read More »

States Pull Back on Covid Data Even Amid Delta Surge

Two state government websites in Georgia recently stopped posting updates on covid-19 cases in prisons and long-term care facilities, just as the dangerous delta variant was taking hold. Data has been disappearing recently in other states as well. Florida, for example, now reports covid cases, deaths and hospitalizations once a week, instead of daily, as …

States Pull Back on Covid Data Even Amid Delta Surge Read More »

Medicaid Vaccination Rates Founder as States Struggle to Immunize Their Poorest Residents

Medicaid enrollees are getting vaccinated against covid-19 at far lower rates than the general population as states search for the best strategies to improve access to the shots and persuade those who remain hesitant. Efforts by state Medicaid agencies and the private health plans that most states pay to cover their low-income residents has been …

Medicaid Vaccination Rates Founder as States Struggle to Immunize Their Poorest Residents Read More »

KHN’s ‘What the Health?’: Vaccine Approval Moves the Needle on Covid

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The Food and Drug Administration gave full approval this week to the covid-19 vaccine from Pfizer and BioNTech, which will henceforth be known as “Comirnaty.” It is …

KHN’s ‘What the Health?’: Vaccine Approval Moves the Needle on Covid Read More »

New Montana Law Sows Confusion, Defiance Over School Quarantines

As classes get underway this week and next, Montana school and county health officials are grappling with how a new state law that bans vaccine discrimination should apply to quarantine orders for students and staffers exposed to covid-19. It’s the latest fallout from the law that says businesses and governmental entities can’t treat people differently …

New Montana Law Sows Confusion, Defiance Over School Quarantines Read More »

What Missouri Learned the Hard Way About Rapid Covid Testing in Schools

Early in the tumultuous 2020-21 school year, Missouri officials made a big gamble: set aside roughly 1 million rapid covid tests for the state’s K-12 schools in hopes of quickly identifying sick students or staff members. The Trump administration had spent $760 million to procure 150 million rapid-response antigen tests from Abbott Laboratories, including 1.75 …

What Missouri Learned the Hard Way About Rapid Covid Testing in Schools Read More »

Trinity Health Mid-Atlantic to deploy NeuroFlow’s mental health tools across 3 hospitals

Through a program funded by Independence Blue Cross Foundation, 1,800 frontline healthcare workers across the three Pennsylvania-based hospitals will gain access to NeuroFlow’s technology, which will measure and track their mental health symptoms and provide support via educational resources and a clinical care team.

Scant on details, J&J claims it has data supporting Covid-19 booster shots

As U.S. plans for Covid-19 booster shots unfold, Johnson & Johnson is angling to join the mix, reporting data that it says support a second shot of its vaccine. But the data the company points to are sparse and it’s not entirely clear they support booster shots.

Pandemia revela una creciente crisis de suicidios en comunidades de color

Rafiah Maxie ha sido trabajadora social clínica en el área de Chicago durante una década. En todo ese tiempo, vio al suicidio como un problema más frecuente entre los hombres caucásicos de mediana edad. Hasta el 27 de mayo de 2020. Ese día, su hijo de 19 años, Jamal Clay, a quien le encantaba tocar …

Pandemia revela una creciente crisis de suicidios en comunidades de color Read More »

UK real-world study finds COVID-19 jab protection wanes

A study has found evidence that protection from the AstraZeneca and Pfizer/BioNTech COVID-19 vaccines starts fall off after a few months, but a UK government advisor says there’s no need to rush into a large-scale booster campaign. The results of the ZOE COVID study found that initial protection against infection a month after the second …

UK real-world study finds COVID-19 jab protection wanes Read More »

Hot Spots Where Covid Vaccination Lags Push Experimental Antibody Treatment

For months, Joelle Ruppert was among the millions of Americans who are covid vaccine holdouts. Her reluctance, she said, was not so much that she opposed the new vaccines but that she never felt “compelled” by the evidence supporting their experimental use. Nonetheless, after she fell ill with covid last month, Ruppert, a Florida preschool …

Hot Spots Where Covid Vaccination Lags Push Experimental Antibody Treatment Read More »

Delta Double-Down: A Universal Health Plan Is Long Overdue.

By MIKE MAGEE On March 25, 1966, during the Poor People’s March that the Rev. Martin Luther King Jr. said, “Of all the forms of inequality, injustice in health care is the most shocking and inhumane.” This week, my niece in Orlando, Florida, sent her 8-year old son, masked, back to public school. He has …

Delta Double-Down: A Universal Health Plan Is Long Overdue. Read More »

Pfizer and BioNTech’s Comirnaty Receive the US FDA’s Approval to Prevent COVID-19 in Individuals Aged 16 Years and Older

Shots: The approval is based on the longer-term follow-up data from the P-III trial that showed high efficacy and favorable safety profile through 6mos. after the second dose The vaccine will now be marketed as Comirnaty and is fully approved for the prevention of COVID-19 in individuals aged ≥16 yrs. The companies also plan to …

Pfizer and BioNTech’s Comirnaty Receive the US FDA’s Approval to Prevent COVID-19 in Individuals Aged 16 Years and Older Read More »

Analysis: Care for the unvaccinated may be costing U.S. healthcare system $2.3B

The report, released by Kaiser Family Foundation and the Peterson Center on Healthcare, details the high cost of Covid care for the unvaccinated. In fact, the analysis indicates the figure could be even higher than $2.3 billion, as the authors did not take into account the cost of outpatient treatment for Covid-19.

Pfizer, BioNTech Covid-19 vaccine is awarded full FDA approval

Full FDA approval makes the Pfizer/BioNTech Covid-19 vaccine the first to reach that milestone. But the regulatory decision also flagged a potential risk of heart inflammation, particularly in young males, and the agency has asked the companies to conduct additional clinical research.

FDA grants full approval to Pfizer/BioNTech COVID jab

Pfizer and BioNTech’s COVID-19 vaccine was the first to get emergency use authorisation (EUA) from the FDA, and has also become the first to get full regulatory approval in the US. The regulator has cleared the vaccine – now officially given the trade name Comirnaty – to prevent COVID-19 in people aged 16 or more, …

FDA grants full approval to Pfizer/BioNTech COVID jab Read More »

Zydus’ ZyCoV-D Receives the DCGI’s EUA for the Treatment of COVID-19

Shots: The DCGI has granted a EUA for ZyCoV-D which is the world’s first plasmid DNA vaccine for COVID-19. The company is planning to seek approval for the two-dose regimen of the vaccine ZyCoV-D will become India’s first vaccine for adolescents aged 12-18 yrs. The vaccine is safe and well-tolerated ZyCoV-D is a three-dose, needle-free, …

Zydus’ ZyCoV-D Receives the DCGI’s EUA for the Treatment of COVID-19 Read More »

COVID prompts another milestone, as India clears first DNA vaccine

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. This is the first DNA vaccine to ever receive regulatory authorisation anywhere in the world, the first COVID-19 jab approved in India to treat children …

COVID prompts another milestone, as India clears first DNA vaccine Read More »

Readers and Tweeters Ponder Vaccines and Points of Fairness

Letters to the Editor is a periodic feature. We welcome all comments and will publish a selection. We edit for length and clarity and require full names. Higher Insurance Rates for the Unvaccinated? Snuff Out That Idea This is about Dr. Elisabeth Rosenthal’s comments on “All In With Chris Hayes” (“Analysis: Don’t Want a Vaccine? Be Prepared to …

Readers and Tweeters Ponder Vaccines and Points of Fairness Read More »

Pandemic Unveils Growing Suicide Crisis for Communities of Color

This story is a collaboration between KHN and “Science Friday.” Listen to the conversation between KHN national correspondent Aneri Pattani and John Dankosky, Science Friday’s director of news and radio projects. Rafiah Maxie has been a licensed clinical social worker in the Chicago area for a decade. Throughout that time, she’d viewed suicide as a problem …

Pandemic Unveils Growing Suicide Crisis for Communities of Color Read More »

Lessons learned from the Covid vaccine development process

As the world’s focus has turned to getting the COVID-19 vaccines out as widely and rapidly as possible, it’s easy to almost forget about the incredible global effort that developed them in record time. But it is important to take some time to reflect on the process that got us here, so that we can …

Lessons learned from the Covid vaccine development process Read More »

The State of Patient Access 2.0: 4 opportunities to strengthen the digital experience

“93% of providers say creating a better patient experience remains a top priority, up 3% from last year.” – Experian Health’s State of Patient Access, June 2021 Download now In November 2020, we surveyed patients and providers for their sentiments on how patient access changed because of the pandemic. During this time, patients welcomed the …

The State of Patient Access 2.0: 4 opportunities to strengthen the digital experience Read More »

Journalists Investigate Vaccine Mandates and Health Worker Burnout

KHN Midwest correspondent Lauren Weber discussed how public health workers are struggling to deal with the pandemic on the “Healthy You: Surviving a Pandemic” podcast on Aug. 12. She also spoke about covid-19 news on WAMU’s “1A” on Aug. 13. Click here to hear Weber on “Health You: Surviving a Pandemic” Click here to hear …

Journalists Investigate Vaccine Mandates and Health Worker Burnout Read More »

AstraZeneca drug succeeds in Covid-19 prevention; regulatory filings on the way

An AstraZeneca antibody drug for Covid-19 has clinical data showing the drug reduced the risk of infection by 77%. With the results, the pharmaceutical giant pulls ahead of other companies developing injectable versions of antibody drugs for Covid-19 prevention.

PROVENT trial puts AZ COVID antibody combo back on track

AstraZeneca’s AZD7442 has shown that it can prevent COVID-19 infection when given to healthy patients – the first time this has been demonstrated by a long-acting antibody-based drug. The results of the almost 5,200-patient PROVENT study show that pre-exposure prophylaxis using the antibody combination reduced the risk of developing symptomatic COVID-19 by 77% compared to …

PROVENT trial puts AZ COVID antibody combo back on track Read More »

AstraZeneca’s AZD7442 Meets its Primary Endpoint in P-III PROVENT Study for the Prevention of COVID-19

Shots: The P-III PROVENT, pre-exposure prophylaxis trial evaluates safety & efficacy of AZD7442 (300mg, IM) vs PBO in 5197 patients in a ratio (2:1) with COVID-19 across 87 sites in the US, UK, Spain, France & Belgium Results: AZD7442 (1st LAAB combination) showed a 77% reduction in risk of developing symptomatic COVID-19, 75% of patients …

AstraZeneca’s AZD7442 Meets its Primary Endpoint in P-III PROVENT Study for the Prevention of COVID-19 Read More »

After Pandemic Ravaged Nursing Homes, New State Laws Protect Residents

When the coronavirus hit Martha Leland’s Connecticut nursing home last year, she and dozens of other residents contracted the disease while the facility was on lockdown. Twenty-eight residents died, including her roommate. “The impact of not having friends and family come in and see us for a year was totally devastating,” she said. “And then, …

After Pandemic Ravaged Nursing Homes, New State Laws Protect Residents Read More »

Biden’s No-Jab-No-Job Order Creates Quandary for Nursing Homes

President Joe Biden’s edict that nursing homes must ensure their workers are vaccinated against covid-19 presents a challenge for an industry struggling to entice its lowest-paid workers to get shots without driving them to seek employment elsewhere. Although 83% of residents in the average nursing facility are vaccinated, only 61% of a home’s workers are …

Biden’s No-Jab-No-Job Order Creates Quandary for Nursing Homes Read More »

‘We Sent a Terrible Message’: Scientists Say Biden Jumped the Gun With Vaccine Booster Plan

The Biden administration’s plans to make covid-19 booster shots available next month has drawn a collective scream of protest from the scientific community. As some scientists see it, the announcement is rash and based on weak evidence, and they worry it could undercut confidence in vaccines with no clear benefit of controlling the pandemic. Meanwhile, …

‘We Sent a Terrible Message’: Scientists Say Biden Jumped the Gun With Vaccine Booster Plan Read More »

School or ‘Russian Roulette’? Amid Delta Variant and Lax Mask Rules, Some Parents See No Difference

The child had just started kindergarten. Or, as her mother called it, “Russian roulette.” That’s because her school district in Grand Junction, Colorado, experienced one of the nation’s first delta-variant outbreaks last spring, and now school officials have loosened the rules meant to protect against covid-19. The mother, Venessa, who asked not to be named …

School or ‘Russian Roulette’? Amid Delta Variant and Lax Mask Rules, Some Parents See No Difference Read More »

It takes a pandemic: Mental Health parity may finally have its day!

By EMILY EVANS Emily Evans is the health policy guru at equity research company HedgeEye. She sends out these reports in emails to her clients regularly but (since I asked nicely) she allowed me to publish this one from late last week on THCB. You can catch Emily in person on the “How Much Are These …

It takes a pandemic: Mental Health parity may finally have its day! Read More »

KHN’s ‘What the Health?’: Booster Time

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. As covid-19 cases in the U.S. continue to rise, the Biden administration is countering with new strategies. The latest efforts include preparing for vaccine boosters starting this …

KHN’s ‘What the Health?’: Booster Time Read More »

To Stoke Rural Vaccination Rates, Trusted Farmers Are Asked to Spread Word

When he became eligible for the coronavirus vaccine in Illinois, Tom Arnold, 68, said he didn’t need any convincing. He raises cattle, hogs and chickens in Elizabeth, a small town in the state’s northwestern corner. After all, who better to understand why herd immunity matters than a herdsman? “Being a livestock producer, I’m well aware …

To Stoke Rural Vaccination Rates, Trusted Farmers Are Asked to Spread Word Read More »

If the Unvaccinated Want to Work, They Face a Series of Hurdles

With the delta variant surging, a growing number of employers are tiring of merely cajoling workers to get vaccinated against covid-19 and are following President Joe Biden’s protocol for federal workers: Either show proof of vaccination, or mask up and get regular testing if you want to work on-site. The federal government — the nation’s …

If the Unvaccinated Want to Work, They Face a Series of Hurdles Read More »

Covid Politics and Fatigue Work Against Contact-Tracing Foot Soldiers

Health departments nationwide scaled back their contact tracing in late spring or early summer when covid-19 cases started to decrease as vaccination efforts took center stage. Then delta hit. Now state and local health departments are trying to build back operations with depleted resources, as covid fatigue among their workers and the public alike complicate …

Covid Politics and Fatigue Work Against Contact-Tracing Foot Soldiers Read More »

HHS cites real-world data for Covid-19 boosters; WHO says the science is still out

In announcing plans to offer Covid-19 booster shots, federal health officials cited declining vaccine efficacy shown by real-world studies. But the World Health Organization said the science is less than clear about booster shots, adding that it’s ethically wrong to give third shots when so many around the world are waiting for their first one.

Reports: 1 in 10 adults delayed care in spring amid trailing healthcare utilization levels

According to two new reports, hospital admissions were about 85% of what was expected based on historic patterns at the beginning of April, and in the same month, 11% of adults reported delaying care because of Covid, including 16% of Hispanic and 13% of Black adults.

Lo que debes saber sobre el refuerzo de la vacuna contra covid

La administración de Biden anunció el miércoles 18 de agosto planes para ofrecer refuerzos de la vacuna contra covid-19 a todos los adultos estadounidenses a partir del próximo mes, y dijo que los datos recientes, incluidos algunos disponibles solo en los últimos días, jugaron un papel en esa decisión. “Si esperan a que suceda algo …

Lo que debes saber sobre el refuerzo de la vacuna contra covid Read More »

Amid Actemra shortage, WHO asks Roche to ensure equitable access

Roche’s arthritis drug Actemra has become a key treatment for people with severe COVID-19, leading to shortages, and the World Health Organisation (WHO) wants the company to ensure that supplies don’t just go to wealthy countries. Earlier this week Roche’s Genentech unit said it was facing unprecedented demand for Actemra (tocilizumab) – known as RoActemra …

Amid Actemra shortage, WHO asks Roche to ensure equitable access Read More »

Welcome to the COVIDome, a new tool for COVID-19 R&D

Take a cohort of people hospitalised with COVID-19 and a group of negative controls, carry out extensive biological profiling of both groups and place all the information in a database. What do you get? A new R&D toolkit called the COVIDome, which has been shared by its developers in the hope that it could accelerate …

Welcome to the COVIDome, a new tool for COVID-19 R&D Read More »

Rush to Boosters Sparks Confusion, Differing Recommendations

When the Food and Drug Administration announced last week that a third dose of Moderna or Pfizer-BioNTech covid-19 vaccine may boost the immunity of some people who are immunocompromised, officials repeated their stance that fully vaccinated, healthy people do not need another dose. With this caveat: “The FDA is actively engaged in a science-based, rigorous …

Rush to Boosters Sparks Confusion, Differing Recommendations Read More »

Federal Vaccine Program Hasn’t Helped Those Whose Lives Were Altered by Covid Shot

Angela Marie Wulbrecht jumped at the first chance to get a covid-19 vaccine, driving three hours from her Santa Rosa, California, home to a mass-vaccination site on Jan. 19. Twelve minutes after her Moderna shot, she stumbled into the paramedic tent with soaring blood pressure and a racing heartbeat. And so began a calvary of …

Federal Vaccine Program Hasn’t Helped Those Whose Lives Were Altered by Covid Shot Read More »

Science Shows Mask-Wearing Is Largely Safe for Children

Florida Gov. Ron DeSantis is one of a handful of Republican governors trying to block school districts from requiring masks in the classroom.  Under DeSantis’ direction, the state health department adopted a rule that lets families opt out of locally ordered school mask mandates. The State Board of Education approved another rule that allows parents to secure vouchers for their …

Science Shows Mask-Wearing Is Largely Safe for Children Read More »

Gritstone secures CEPI funding to test Covid vaccine; first focus is South Africa

Gritstone bio is developing Covid-19 vaccines that use self-amplifying messenger RNA, which is intended to further boost the immune response compared to mRNA alone. The company also says its vaccine candidates may be able to protect against variants of the novel coronavirus.

MHRA clears Moderna COVID vaccine for 12 to 17 year olds

The Moderna COVID-19 vaccine has become the second jab to be authorised for use in England, Scotland and Wales in children aged 12 to 17 after getting the nod from the Medicines and healthcare products Regulatory Agency (MHRA). It joins the Pfizer/BioNTech vaccine in being an option for that age group, having been approved in …

MHRA clears Moderna COVID vaccine for 12 to 17 year olds Read More »

Have Vaccines, Will Travel: On the Road With a Covid Entrepreneur

VIRGINIA CITY, Mont. — While many businesses in this southwestern Montana “ghost town” reel in tourists with its mining and Wild West vigilante past, one businessman arrived offering a modern product: covid-19 vaccines. Kyle Austin, a traveling pharmacist, set up his mobile clinic in Virginia City on a recent Saturday, the latest stop on his …

Have Vaccines, Will Travel: On the Road With a Covid Entrepreneur Read More »

‘Tainted’ Blood: Covid Skeptics Request Blood Transfusions From Unvaccinated Donors

The nation’s roiling tensions over vaccination against covid-19 have spilled into an unexpected arena: lifesaving blood transfusions. With nearly 60% of the eligible U.S. population fully vaccinated, most of the nation’s blood supply is now coming from donors who have been inoculated, experts said. That’s led some patients who are skeptical of the shots to …

‘Tainted’ Blood: Covid Skeptics Request Blood Transfusions From Unvaccinated Donors Read More »

Pfizer, BioNTech file for FDA approval of COVID booster shot

Pfizer and BioNTech have formally asked for FDA approval of a third dose of their COVID-19 vaccine BNT162b2 in people aged over 16, as the US prepares to get its booster campaign underway. The two companies have submitted data from a phase 1 trial in support of the booster dose to the US regulator, and …

Pfizer, BioNTech file for FDA approval of COVID booster shot Read More »

Heces: la nueva herramienta de detección de covid y otras enfermedades

Desde la reapertura del campus de la Universidad de California-San Diego, el pasado verano, la institución ha recurrido a estrategias de salud pública de probada eficacia, como las pruebas y el rastreo de contactos. Pero también ha añadido una herramienta a su arsenal: excrementos. Esta herramienta alertó a los investigadores de un 85% de los …

Heces: la nueva herramienta de detección de covid y otras enfermedades Read More »

A New Antibody-Dependent Enhancement Hypothesis

Here’s another post that I will regret writing, but a great many people have asked me about a new preprint that brings up the possibility of antibody-dependent enhancement with the current vaccines and the Delta variant. To be frank, some of the people promoting this seem to be rooting for the virus, just so long …

A New Antibody-Dependent Enhancement Hypothesis Read More »

Merck Reports the Initiation of Rolling Submission to Health Canada for Molnupiravir to Treat COVID-19

Shots: The initiation of a rolling submission to Health Canada for molnupiravir (bid, for 5 days) to treat COVID-19 is based on the P-II interim results from the P-II/III MOVe-OUT clinical trials. The therapy is being developed in collaboration with Ridgeback The submission was accepted under the Minister of Health’s interim order and enables the …

Merck Reports the Initiation of Rolling Submission to Health Canada for Molnupiravir to Treat COVID-19 Read More »

Merck kicks off oral COVID-19 antiviral filing in Canada

Health Canada has started a rolling review of Merck & Co’s molnupiravir, an oral antiviral therapy treatment for COVID-19 partnered with Ridgeback Biotherapeutics. The Canadian regulator will start reviewing early safety, quality and efficacy data for the drug while late-stage clinical trials are still underway, in the hope of approving the drug quickly of results …

Merck kicks off oral COVID-19 antiviral filing in Canada Read More »

The Newest Disease Detection Tool for Covid and Beyond: Poop

Since reopening campus at the University of California-San Diego last summer, university officials have relied on the tried-and-true public health strategies of testing and contact tracing. But they have also added a new tool to their arsenal: excrement. That tool alerted researchers to about 85% of cases in dorms before they were diagnosed, according to …

The Newest Disease Detection Tool for Covid and Beyond: Poop Read More »

In Rural America, Twisting Arms to Take a Covid Vaccine First Takes Trust

CAIRO, Ill. — Lee Wright was hard at work, constructing a nail salon near the city’s abandoned hospital, when Jody Johnson stopped by to introduce himself on a recent afternoon. Johnson, who works for the University of Illinois Extension program, chatted with Wright casually in the summertime heat. For Johnson, it was the first step …

In Rural America, Twisting Arms to Take a Covid Vaccine First Takes Trust Read More »

UK adults asked to record coughs to improve COVID detection

Researchers in the UK are asking adults who have taken a COVID-19 test in the last 72 hours to record themselves coughing, breathing and speaking to help develop new ways to detect infection. The aim is to develop algorithms that could be used to detect COVID-19 remotely – for example before a PCR or lateral …

UK adults asked to record coughs to improve COVID detection Read More »

Organicell on regenerative medicine: the pharmaphorum podcast

In the latest episode of the podcast Dominic Tyer speaks with Dr Maria Ines ‘Mari’ Mitrani, chief science officer at the clinical-stage biopharmaceutical company Organicell Regenerative Medicine. They looked at the development of regenerative medicine and where Organicell hopes to add to that field. Then, with the company pivoting to try and help tackle Covid, they …

Organicell on regenerative medicine: the pharmaphorum podcast Read More »

Mensaje del CEO de Pfizer al público: confíen en nosotros con el refuerzo de la vacuna contra covid

El CEO de Pfizer, Albert Bourla, confiaba en junio en la capacidad de la vacuna de su empresa para proteger contra la variante delta, altamente contagiosa, mientras se diseminaba por el mundo y llenaba de pacientes los hospitales estadounidenses. Apenas unas semanas después, Pfizer comunicó que solicitaría autorización para una vacuna de refuerzo, después que …

Mensaje del CEO de Pfizer al público: confíen en nosotros con el refuerzo de la vacuna contra covid Read More »

‘I Don’t Want to Risk My Life for a Paycheck’: Immunosuppressed People Grapple With Returning to Work

Elizabeth Groenweghe got a kidney transplant 14 years ago. She now takes several medications to prevent her body from rejecting her transplant organ. But these medications also weaken her immune system, putting her at higher risk of becoming seriously ill if she catches covid-19. When the pandemic began last year, Groenweghe, 29, worked from home …

‘I Don’t Want to Risk My Life for a Paycheck’: Immunosuppressed People Grapple With Returning to Work Read More »

FDA authorizes Covid-19 booster shots, but only for the immunocompromised

Covid-19 vaccine booster shots are now authorized for organ transplant patients and others who have weakened immune systems. The FDA based its update on the results of two small studies that tested third shots of the mRNA Covid vaccines from Moderna and Pfizer/BioNTech.

Celltrion’s Regdanvimab (CT-P59) Receives the ANVISA’s EUA for the Treatment of COVID-19 in Brazil

Shots: The EUA is based on P-III study evaluating regdanvimab vs PBO in adults with COVID-19 who do not require supplemental oxygen & are at high risk of progression to severe COVID-19 The results demonstrated a 72% reduction in risk of COVID-19 related hospitalization or death in high-risk patients & 70% for all patients, shortened …

Celltrion’s Regdanvimab (CT-P59) Receives the ANVISA’s EUA for the Treatment of COVID-19 in Brazil Read More »

Pfizer CEO to Public: Just Trust Us on the Covid Booster

Pfizer CEO Albert Bourla was confident in June about the ability of his company’s vaccine to protect against the highly contagious delta variant, as it marched across the globe and filled U.S. hospitals with patients. “I feel quite comfortable that we cover it,” Bourla said. Just weeks later, Pfizer said it would seek authorization for …

Pfizer CEO to Public: Just Trust Us on the Covid Booster Read More »

FDA authorises COVID booster jabs for at-risk people

The FDA has cleared the use of third dose of either the Pfizer/BioNTech or Moderna COVID-19 vaccines for people with weakened immune systems, but stopped short of a broader booster campaign. The emergency use authorisation (EUA) for the two mRNA-based vaccines has been amended so they can be used for solid organ transplant recipients or …

FDA authorises COVID booster jabs for at-risk people Read More »

KHN’s ‘What the Health?’: The Senate Acts

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The Senate has set the stage for a busy fall that will include debate on a broad array of health issues, such as prescription drug prices, Medicare …

KHN’s ‘What the Health?’: The Senate Acts Read More »

Más embarazadas con covid en cuidados intensivos, expertos enfatizan que deben vacunarse

Los Centros para el Control y Prevención de Enfermedades (CDC) están duplicando su recomendación de que las mujeres embarazadas reciban la vacuna contra covid-19, a la luz de nuevos datos que subrayan su seguridad y eficacia durante el embarazo. Esta recomendación llega en un momento en que los médicos de todo el país informan de …

Más embarazadas con covid en cuidados intensivos, expertos enfatizan que deben vacunarse Read More »

UK cues up more Pfizer/BioNTech vaccines as price row looms

The UK government has started ordering COVID-19 vaccines for a 2022 booster campaign, including a 32 million-dose order for the Pfizer/BioNTech shot, even before third doses for 2021 have been given the go-ahead. A report in The Times claims that the government is paying £22 a dose – up from an earlier price of £18 …

UK cues up more Pfizer/BioNTech vaccines as price row looms Read More »

Reading, ’Rithmetic and Resisting Covid: The New 3 R’s as Kids Head Back to School

When kids head back to school this fall, for some it will be the first time they’ve been in a real classroom with other students since the pandemic began. Even if they attended classes in person last year, the spread of the highly transmissible delta variant of covid-19 will require a new safety calculation, particularly …

Reading, ’Rithmetic and Resisting Covid: The New 3 R’s as Kids Head Back to School Read More »

Getting a Covid Vaccine During Pregnancy Even More Urgent as ICU Beds Fill Up

The Centers for Disease Control and Prevention is doubling down on its recommendation that people who are pregnant get the covid-19 vaccine, in light of new data underscoring its safety and effectiveness throughout pregnancy. This recommendation comes at a time when doctors across the country are reporting an uptick in the number of unvaccinated pregnant …

Getting a Covid Vaccine During Pregnancy Even More Urgent as ICU Beds Fill Up Read More »

SK Bio’s COVID vaccine will start phase 3 study versus AZ jab

South Korea’s SK Bioscience has been given the all-clear to start a phase 3 trial of its COVID-19 vaccine GBP510 that will compare the shot directly with AstraZeneca’s Vaxzevria. It is the first COVID-19 vaccine developed in South Korea to reach the pivotal trial stage, and from the earliest stages of its development has been …

SK Bio’s COVID vaccine will start phase 3 study versus AZ jab Read More »

Public Favors Masks in Classrooms but Balks at Mandating Vaccinations for Students

As the spread of the delta variant threatens the safety of classrooms, a poll released Wednesday found nearly two-thirds of parents support schools’ requiring unvaccinated students age 5 or older and teachers to wear masks. A majority of parents, however, oppose requiring students now eligible for a covid vaccine to get one, with one Black …

Public Favors Masks in Classrooms but Balks at Mandating Vaccinations for Students Read More »

DeSantis’ Executive Order Is Misleading About Lack of Scientific Support for Masking in Schools

The Centers for Disease Control and Prevention’s recent guidance on students and masking “lacks a well-grounded scientific justification.” Florida Gov. Ron DeSantis in a July 30 executive order On July 30, Florida Gov. Ron DeSantis issued an executive order stating that schools couldn’t mandate that their students wear masks, and that it should be up …

DeSantis’ Executive Order Is Misleading About Lack of Scientific Support for Masking in Schools Read More »

BioNTech says repeat doses may be better than modified COVID-19 jab

BioNTech has suggested that giving booster doses of its current Comirnaty (BNT162b2) COVID-19 vaccine may be a preferable strategy to modifying the Pfizer-partnered shot. The comments came on the German biotech’s second-quarter results call, during which BioNTech raised its forecasts for revenues it will book from sales of the vaccine to €15.9 billion (almost $19 …

BioNTech says repeat doses may be better than modified COVID-19 jab Read More »

A Quarter of US Hospitals, and Counting, Demand Workers Get Vaccinated. But Not Here.

Hospitals coast to coast are demanding their employees get vaccinated against covid as the highly contagious delta variant tears through populations with low vaccination rates. Nearly 1,500 hospitals — roughly a quarter of all hospitals in the U.S. —now require staffers to get a covid vaccine, said Colin Milligan, a spokesperson for the American Hospital …

A Quarter of US Hospitals, and Counting, Demand Workers Get Vaccinated. But Not Here. Read More »

‘The Vaccination Queen’: Nurse Practitioner Takes Covid Shots House to House in Puerto Rico

MAYAGÜEZ, PUERTO RICO — Abigail Matos-Pagán entered a bright-blue house in Mayagüez earlier this summer and was met by Beatriz Gastón, who quietly led the way to her mother’s small room. Matos-Pagán had come to provide a covid-19 vaccine for Wildelma Gastón, 88, whose arthritis and other health concerns confine her to bed. Wildelma Gastón …

‘The Vaccination Queen’: Nurse Practitioner Takes Covid Shots House to House in Puerto Rico Read More »

A California Bill Would Limit Protests at Vaccination Sites. Does It Violate the First Amendment?

SACRAMENTO, Calif. — A proposal sailing through the California legislature that aims to stop people from getting harassed outside of vaccination sites is raising alarms among some First Amendment experts. If it becomes law, SB 742 would make it punishable by up to six months in jail and/or a maximum fine of $1,000 to intimidate, …

A California Bill Would Limit Protests at Vaccination Sites. Does It Violate the First Amendment? Read More »

“La reina de la vacunación”: enfermera lleva las dosis contra covid de casa en casa en Puerto Rico

MAYAGÜEZ, PUERTO RICO – Abigail Matos-Pagán llegó a una casa de color azul brillante en Mayagüez, en donde la recibió Beatriz Gastón, quien en silencio la condujo a la pequeña habitación de su madre. Matos-Pagán llevaba una vacuna contra covid-19 para Wildelma Gastón, de 88 años, quien está confinada en una cama por su artritis …

“La reina de la vacunación”: enfermera lleva las dosis contra covid de casa en casa en Puerto Rico Read More »

Journalists Assess the Latest Covid Surge and the Nation’s Vaccination Effort

KHN freelancer Mark Kreidler discussed why professional athletes are not taking a more affirmative role in pushing covid vaccines on Newsy on Tuesday. Click here to watch Kreidler on Newsy Read Kreidler’s “Big Leagues Balk at Endorsing Vaccination“ KHN Midwest correspondent Cara Anthony discussed masking mandates, vaccine efficacy and breakthrough covid cases on Illinois Public …

Journalists Assess the Latest Covid Surge and the Nation’s Vaccination Effort Read More »

Déjà Vu? Consumers Scramble for Covid Tests in Hard-Hit Areas

Andrea Mosterman, an associate professor of history at the University of New Orleans, was already dismayed that she had to wait three days to secure a covid-19 test at a Walgreens near her home after being in contact with someone who had tested positive. But on Sunday, when she showed up at the pharmacy drive-thru, …

Déjà Vu? Consumers Scramble for Covid Tests in Hard-Hit Areas Read More »

Moderna COVID-19 jab sales rocket to $4.2 billion in second quarter

Moderna made a massive $4.2 billion from sales of just under 200 million doses of its COVID-19 vaccine, taking its tally since approval to around $6 billion from 302 million shots. The tally makes the SpikeVax (mRNA-1273) vaccine the second biggest seller behind Pfizer/BioNTech’s Comirnaty, which pulled in $7.8 billion in the second quarter and …

Moderna COVID-19 jab sales rocket to $4.2 billion in second quarter Read More »

Clarity on Covid Count: Pandemic’s Toll on Seniors Extended Well Beyond Nursing Homes

As covid-19 resurges across the country, driven by the highly infectious delta variant, experts are extending our understanding of the pandemic’s toll on older adults — the age group hit hardest by the pandemic. New research offers unexpected insights. Older adults living in their own homes and apartments had a significantly heightened risk of dying …

Clarity on Covid Count: Pandemic’s Toll on Seniors Extended Well Beyond Nursing Homes Read More »

KHN’s ‘What the Health?’: Delta Blues

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The U.S. is experiencing another surge of covid-19, particularly in Southern states where vaccination rates are generally lower than in other regions. But partisan fights rage on …

KHN’s ‘What the Health?’: Delta Blues Read More »

Análisis: ¿No quieres una vacuna? Prepárate para pagar más por tu seguro de salud

La tasa de vacunación contra covid-19 en Estados Unidos es de alrededor del 60% desde los 12 años en adelante. Esto no es suficiente para alcanzar la llamada inmunidad colectiva, y en estados como Missouri, donde varios condados tienen tasas de vacunación inferiores al 25%, los hospitales están abrumados por brotes graves de la variante …

Análisis: ¿No quieres una vacuna? Prepárate para pagar más por tu seguro de salud Read More »

Providers will likely face more lawsuits against vaccine mandates. But they are also more likely to win.

Providers’ legal defense against lawsuits aiming to tear down vaccine mandates is wide-ranging, from making the argument that allowing an unvaccinated worker into their facilities could pose a direct threat to the worker to invoking a 1905 precedent set by the Supreme Court.

UK extends COVID vaccination to 16 and 17-year-olds

The UK government has confirmed that the national COVID-19 vaccination campaign will be extended to include 16 and 17-year-old children, to tackle an increase in spread of the virus in younger age groups. The moves comes on the back of new advice from the Joint Committee on Vaccine and Immunisation (JCVI), which has concluded that …

UK extends COVID vaccination to 16 and 17-year-olds Read More »

“Sabiduría y miedo” llevan al 90% de los adultos mayores de EE.UU. a vacunarse contra covid

En medio del último aumento de casos de covid-19 y hospitalizaciones, Estados Unidos alcanzó el martes 3 de agosto un hito que algunos pensaban que era inalcanzable: el 90% de las personas de 65 años o más están al menos parcialmente vacunadas contra la enfermedad. Esto es más de 49 millones de adultos mayores vacunados. …

“Sabiduría y miedo” llevan al 90% de los adultos mayores de EE.UU. a vacunarse contra covid Read More »

‘Wisdom and Fear’ Lead 90% of U.S. Seniors to Covid Vaccines

Amid the latest surge in covid-19 cases and hospitalizations, the United States on Tuesday hit a milestone that some thought was unattainable: 90% of people 65 and older are at least partly vaccinated against the disease. That’s more than 49 million seniors vaccinated. Overall, 70% of adults have been inoculated, at least partly, and nearly …

‘Wisdom and Fear’ Lead 90% of U.S. Seniors to Covid Vaccines Read More »

Analysis: Don’t Want a Vaccine? Be Prepared to Pay More for Insurance.

America’s covid-19 vaccination rate is around 60% for ages 12 and up. That’s not enough to reach so-called herd immunity, and in states like Missouri — where a number of counties have vaccination rates under 25% — hospitals are overwhelmed by serious outbreaks of the more contagious delta variant. The vaccine resisters offer all kinds of reasons for refusing the free …

Analysis: Don’t Want a Vaccine? Be Prepared to Pay More for Insurance. Read More »

Boost vaccination rates with frictionless self-scheduling

As the country strives to ramp up the pace of COVID-19 vaccinations, providers need to take new approaches to drive registration volume. Healthcare experts are increasingly concerned about the rapid spread of the highly contagious delta variant, which now makes up over 83% of COVID-19 cases. This variant is estimated to be 60% more transmissible …

Boost vaccination rates with frictionless self-scheduling Read More »

Boost vaccination rates with frictionless self-scheduling

It’s time to accelerate the pace of COVID-19 vaccinations. Healthcare experts are increasingly concerned about the rapid spread of the highly contagious delta variant, which now makes up over 83% of COVID-19 cases. This variant is estimated to be 60% more transmissible than previous strains, and while vaccination doesn’t eliminate the risk, it does reduce …

Boost vaccination rates with frictionless self-scheduling Read More »

CMS repeals MA rate disclosure requirement, boosts hospital payments by $2.3B

CMS has finalized its 2022 inpatient payment rule, which will not only repeal part of the price transparency requirements related to Medicare Advantage rates and increase payments to hospitals but will also require facilities to report Covid-19 vaccination uptake among its employees.

PharmaShots Interview: Xencor’s Bassil I. Dahiyat Shares Insight on the US FDA’s Approval of COVID-19 Antibody Treatment Leveraging its Technology

In an interview with PharmaShots, Dr. Bassil I. Dahiyat, President and CEO of Xencor shared his views on the company’s collaborations with BMS and its Xtend XmAb technology. He also shed light on the EUA of Sotrovimab for COVID-19. Shots: The FDA has granted EUA to Vir and GSK’s sotrovimab, which was engineered with Xencor’s …

PharmaShots Interview: Xencor’s Bassil I. Dahiyat Shares Insight on the US FDA’s Approval of COVID-19 Antibody Treatment Leveraging its Technology Read More »

Germany confirms booster COVID jabs will start in September

Germany’s health ministry has said it will start offering booster COVID-19 vaccines to vulnerable people from next month, amid concerns about rising cases of the delta variant of the coronavirus. Health Minster Jens Spahn said the decision was also taken because of concerns that the immune response stimulated by COVID-19 vaccines may start to diminish …

Germany confirms booster COVID jabs will start in September Read More »

Regeneron Reports the EUA Expansion for REGEN-COV (casirivimab and imdevimab) to Treat COVID 19

Shots: The EUA is based on data from several clinical trials, including P-III trial evaluating REGEN-COV (SC injection or IV infusion) vs PBO in high-risk patients with COVID-19 for post-exposure prophylaxis. The trial is jointly run with the NIAID The results showed 81% reduction in the risk of symptomatic infections while 62% reduction in asymptomatic …

Regeneron Reports the EUA Expansion for REGEN-COV (casirivimab and imdevimab) to Treat COVID 19 Read More »

Restoring a Sense of Belonging: The Unsung Importance of Casual Relationships for Older Adults

In May, Vincent Keenan traveled from Chicago to Charlottesville, Virginia, for a wedding — his first trip out of town since the start of the pandemic. “Hi there!” he called out to customers at a gas station where he’d stopped on his way to the airport. “How’s your day going?” he said he asked the …

Restoring a Sense of Belonging: The Unsung Importance of Casual Relationships for Older Adults Read More »

Self-service patient registration isn’t just for the pandemic

Consumer-led care hit its stride during the pandemic. COVID-19 unlocked healthcare’s digital front door, giving patients more control over how and when they schedule and manage appointments. Unfortunately, while digital patient access has made navigating the healthcare system more convenient and flexible in many ways, consumers are discovering that one of the more frustrating aspects …

Self-service patient registration isn’t just for the pandemic Read More »

Claims That CDC’s PCR Test Can’t Tell Covid From Flu Are Wrong

Claim: “CDC has just announced they will revoke the emergency use authorization of the RT-PCR tests first introduced in 2/20. … Translation: They’ve been adding flu cases to Covid cases when using that test.” Facebook post, July 25, 2021 Posts circulating on Facebook and Instagram claim the Centers for Disease Control and Prevention will stop …

Claims That CDC’s PCR Test Can’t Tell Covid From Flu Are Wrong Read More »

Facing Recall, Newsom Draws Support from Health Care Allies

SACRAMENTO, Calif. — Californians upset with Gov. Gavin Newsom’s pandemic rules — which shuttered businesses, kept schoolkids at home and mandated masks — helped fuel the September recall election that could spell the end of his political career. But among the allies rushing to Newsom’s defense are doctors, nurses, dentists and other health care interests …

Facing Recall, Newsom Draws Support from Health Care Allies Read More »

Health literacy in the time of COVID-19

In a time when much of the media’s focus is on the ongoing COVID-19 pandemic and the differences in vaccination rates between various regions, countries, and socioeconomic groups, improving health literacy has never been more important. Impetus Digital’s Natalie Yeadon explores why. Health literacy is a complex phenomenon that involves both individuals and their local …

Health literacy in the time of COVID-19 Read More »

Bus Stop by Bus Stop, Denver-Area Officials Microtarget Vaccine Hesitancy

AURORA, Colo. — John Letson had seen too many apocalyptic movies to feel comfortable getting a covid-19 vaccine initially. “I was completely against it,” the 40-year-old movie buff said, referencing “I Am Legend” and “Children of Men,” in which humanity is in jeopardy, as examples of what could go wrong. “I think an untested thing …

Bus Stop by Bus Stop, Denver-Area Officials Microtarget Vaccine Hesitancy Read More »

KHN’s ‘What the Health?’: Hot Covid Summer

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. Predictions of a “hot vax summer” that would let Americans who had their covid immunizations celebrate the waning of the pandemic are turning out to have been …

KHN’s ‘What the Health?’: Hot Covid Summer Read More »

AZ’s COVID-19 jab sales top $1.2bn, but come at a loss

AstraZeneca said this morning that it has made $1.2 billion in sales from its COVID-19 vaccine Vaxzevria in the first half of this year, but making it available at no profit had weighed on its profit margins. R&D expenses leaped 28% in the period, an increase that AZ said was “primarily” a result of its …

AZ’s COVID-19 jab sales top $1.2bn, but come at a loss Read More »

Covid Renews Interest in Radiation, but Docs Caution Against Pilgrimages to Radon-Filled Mines

BOULDER, Mont. — Twice a year, Brian Tichenor makes the 1,200-mile drive each way from his home in Kansas to a defunct uranium mine in Montana, where he takes an elevator 85 feet below the surface to sit amid radioactive radon gas to ease the pain from his chronic eye condition. “I found it like …

Covid Renews Interest in Radiation, but Docs Caution Against Pilgrimages to Radon-Filled Mines Read More »

Technology and empathy help make remote working a success for Elsevier

We at Elsevier were pleased to be one of five companies recognized for their ability to keep remote workers rooted in company culture in this recent Comparably article. Like many organizations during the pandemic, we had to quickly adapt to remote working on a large scale for our international workforce. As the article notes, “Elsevier …

Technology and empathy help make remote working a success for Elsevier Read More »

Unraveling the Mysterious Mutations That Make Delta the Most Transmissible Covid Virus Yet

Upon first inspection, the mutations in the highly contagious delta covid variant don’t look that worrisome. For starters, delta has fewer genetic changes than earlier versions of the coronavirus. “When people saw that the epidemic in India was driven by delta, they did not suspect it would be so bad or overtake other variants,” said …

Unraveling the Mysterious Mutations That Make Delta the Most Transmissible Covid Virus Yet Read More »

AZ says second COVID jab dose isn’t linked to rare clot reaction

A new analysis has suggested that the rare blood clot side effects linked to AstraZeneca’s COVID-19 vaccine Vaxzevria don’t occur after a second dose. The study in The Lancet examined cases of thrombosis with thrombocytopenia syndrome (TTS) from an AZ database encompassing around 5.62 million people who had received two doses of Vaxzevria in the …

AZ says second COVID jab dose isn’t linked to rare clot reaction Read More »

Sign-Up Window for Free COBRA Coverage for Many Laid-Off Workers Closes This Week

After being laid off from her job as a systems analyst for a specialty chemicals company in December, Gabriela de Pompignan opted to hang on to her former employer’s insurance coverage under the federal law known as COBRA. Typically, laid-off workers pick up the total cost of premiums under COBRA, but her company paid roughly …

Sign-Up Window for Free COBRA Coverage for Many Laid-Off Workers Closes This Week Read More »

COVID-19: We don’t need another hero

We’ve all got used to hailing healthcare staff as heroes over the past year. Of course they deserve every ounce of admiration, even though many are uncomfortable with the adulation. But the bigger question is whether this heroic status really represents a healthy situation? Someone once advised me that, when conducting due diligence on a …

COVID-19: We don’t need another hero Read More »

First published data backs CanSino’s inhaled COVID vaccine

Early-stage clinical data with CanSino Biologics’ inhaled COVID-19 vaccine show that it was able to stimulate neutralising antibodies against SARS-CoV-2 at a dose well below that required with intramuscular administration. Published in The Lancet, a phase 1 study conducted in China showed that a two-dose regimen of aerosolised Ad5-nCoV was similar to that achieved with …

First published data backs CanSino’s inhaled COVID vaccine Read More »

Adagio Collaborates with Biocon to Provide COVID-19 Ab Treatment to Patients in India and Other Emerging Markets

Shots: The companies collaborated for Adagio’s ADG20 for both the treatment & prevention of COVID-19 as monothx. or combination regimen Biocon will gain rights to manufacture & commercialize ADG20 for COVID-19 in India and select emerging markets based on the commercial process developed for ADG20. The company will have the access to Adagio’s ongoing P-II/III …

Adagio Collaborates with Biocon to Provide COVID-19 Ab Treatment to Patients in India and Other Emerging Markets Read More »

Boehringer takes alteplase to phase 3 for COVID, but drops antibody

Boehringer Ingelheim’s latecomer antibody therapy for COVID-19 has been side-lined, as the company focuses its attention on its thrombolytic drug alteplase, heading into a phase 3 programme later this year. The decision to discontinue development of BI 767551, an inhaled antibody, has been taken because of the “evolving landscape” in managing the pandemic including the …

Boehringer takes alteplase to phase 3 for COVID, but drops antibody Read More »

Want Fries With That Vaccine? Even at a Fast-Food Restaurant, Pop-Up Clinics See Slow Traffic

SAN BERNARDINO, Calif. — A few months ago, the boxy, teal truck parked outside a McDonald’s in this Inland Empire city might have drawn hundreds of people willing to stand in line for hours under the scorching sun. The truck is San Bernardino County’s mobile vaccine unit, which brings covid-19 vaccines directly to people. But …

Want Fries With That Vaccine? Even at a Fast-Food Restaurant, Pop-Up Clinics See Slow Traffic Read More »

BCBS of Kansas City sues Covid-19 testing provider over alleged price gouging

GS Labs, a Covid-19 testing provider, has submitted over $9.2 million in claims to the insurer as a result of its grossly inflated prices, the lawsuit states. The testing company rejected the claims, saying its “prices accurately reflect the level of service” it provides.

Rapid COVID immune status test launched in UK, Ireland

You’ve had your two COVID-19 jabs, but are you actually protected against infection? That’s a question that a fingerprick test launched today in the UK and Ireland could help to answer. The test – originally developed by US manufacturer Chembio Diagnostics – has been introduced into the UK and Irish markets by Guilford-based Luas Diagnostics …

Rapid COVID immune status test launched in UK, Ireland Read More »

Watch: More Long Covid Cases Seen in Kids

The vast majority of the pandemic’s 4.1 million covid infections in children have been mild. However, doctors are concerned about a growing number of long-haul covid cases and a rare but dangerous inflammatory disease, particularly among Black and Latino children. KHN correspondent Sarah Varney, in collaboration with PBS NewsHour, reports on the phenomena. This story …

Watch: More Long Covid Cases Seen in Kids Read More »

Journalists Dig in on Delta Variant Risks and Opioid Overdose Deaths

KHN Midwest correspondent Lauren Weber discussed outbreaks caused by the covid-19 delta variant in Missouri and elsewhere on Newsy on Thursday. Click here to watch Weber on Newsy Read Weber’s “The Delta Variant Thrives in a State of Political and Public Health Discord“ KHN correspondent Aneri Pattani discussed opioids and the rise in overdose deaths …

Journalists Dig in on Delta Variant Risks and Opioid Overdose Deaths Read More »

Study finds jabs cut severe variant COVID disease after one shot

A real-world study carried out in Canada had found that COVID-19 vaccines from AstraZeneca, Pfizer/BioNTech and Moderna reduce the chances of being hospitalised or dying from variants of concern dramatically, even after a single dose. AstraZeneca’s Vaxzevria was found to 87% effective after against the delta variant, which is now thought to be one of …

Study finds jabs cut severe variant COVID disease after one shot Read More »

Readers and Tweeters Connect the Dots on Topics From Vaccine Development to Long Covid

Letters to the Editor is a periodic feature. We welcome all comments and will publish a selection. We edit for length and clarity and require full names. A Concerned Taxpayer Takes Stock of Vaccine Efforts Your recent article “Novavax’s Effort to Vaccinate the World, From Zero to Not Quite Warp Speed” (July 19) seems to reveal Maryland-based Novavax …

Readers and Tweeters Connect the Dots on Topics From Vaccine Development to Long Covid Read More »

Celltrion Collaborates with Inhalon to Develop Regdanvimab (CT-P59) for the Treatment of COVID-19 at Home

Shots: The companies collaborate to develop IN-006 (an inhaled form of regdanvimab) to treat patients with COVID-19. The results are expected in 2022 Inhalon will start a P-I study of nebulized regdanvimab in the next few mos. & plans to complete at the end of 2021 while the study is funded by $7M from the …

Celltrion Collaborates with Inhalon to Develop Regdanvimab (CT-P59) for the Treatment of COVID-19 at Home Read More »

KHN’s ‘What the Health?’: Delta Changes the Covid Conversation

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The resurgence of covid cases in the U.S. — largely attributable to the much more contagious delta variant — has given policymakers the jitters. The Biden administration …

KHN’s ‘What the Health?’: Delta Changes the Covid Conversation Read More »

ViewPoints Article: Ethno-Pharma- An Emerging Sector

The Healthcare sector in 2021 is evolving to a greater extent owing to the initiatives and advancements taking place to futureproof the healthcare facilities from uncertain, unwanted, and deadly events like Covid-19. These advancements are happening while keeping the patients at the center with more focus on preventive and immune health.  Now while talking about …

ViewPoints Article: Ethno-Pharma- An Emerging Sector Read More »

COVID-19: Celltrion’s therapeutic option

In just over a year, Celltrion Healthcare says it has identified and delivered a potential treatment for COVID-19. pharmaphorum spoke to Kwon Ki-sung, Head of Celltrion’s R&D unit, to learn more. Celltrion’s COVID-19 therapeutic, CT-P59, is a monoclonal antibody (mAb) with activity against COVID-19. It was identified as a potential treatment through the screening of …

COVID-19: Celltrion’s therapeutic option Read More »

Big Leagues Balk at Endorsing Vaccination

Santa Clara County, where the San Francisco 49ers train and play their NFL home games, has one of the highest covid vaccination rates in California. As of July 11, more than 76% of its vaccine-eligible residents were fully vaccinated, partly because the county and the 49ers franchise turned Levi’s Stadium into a mass inoculation site …

Big Leagues Balk at Endorsing Vaccination Read More »

Wildfire Smoke Drives People in Low-Vaccinated Areas Indoors, Raising Outbreak Fears

MISSOULA, Mont. — Missoula’s new downtown library was teeming with people who might typically spend a Saturday afternoon hiking, biking or otherwise making the most of Montana’s abundant outdoor recreation. One look at the soupy haze blanketing the city and it was clear why. “We’re definitely trying to stay out of the smoke,” Charlie Booher …

Wildfire Smoke Drives People in Low-Vaccinated Areas Indoors, Raising Outbreak Fears Read More »

How Well Does the J&J Vaccine Work Against the Delta Variant?

That’s a question that’s on a lot of people’s minds, because frankly, we have answers that seem to disagree with each other. Let’s have a look: For one, there’s this letter in the NEJM from researchers at Beth Israel Deaconess hospital and from Janssen (J&J’s pharma branch). That’s a look at immunity in 20 patients …

How Well Does the J&J Vaccine Work Against the Delta Variant? Read More »

ViewPoints Interview: BD’s Tony Ezell Shares Insights on the Collaboration with USATF to Provide COVID – 19 Testing for US Athletes

In an interview with PharmaShots, Tony Ezell, President, North America and Chief Marketing Officer, BD shares its agreement with the USA Track and Field team for COVID-19 testing for the Olympic Trials. Shots: BD’s partnership with USATF is part of the company’s commitment to helping get people back to their normal lives The BD Veritor …

ViewPoints Interview: BD’s Tony Ezell Shares Insights on the Collaboration with USATF to Provide COVID – 19 Testing for US Athletes Read More »

Analysis: Necessary or Not, Covid Booster Shots Are Probably on the Horizon

The drugmaker Pfizer recently announced that vaccinated people are likely to need a booster shot to be effectively protected against new variants of covid-19 and that the company would apply for Food and Drug Administration emergency use authorization for the shot. Top government health officials immediately and emphatically announced that the booster isn’t needed right …

Analysis: Necessary or Not, Covid Booster Shots Are Probably on the Horizon Read More »

The Delta Variant Thrives in a State of Political and Public Health Discord

ST. LOUIS — The day after Missouri Gov. Mike Parson finished his bicentennial bus tour to drum up tourism to the state in mid-July, Chicago issued a travel advisory warning about visiting Missouri. Earlier this summer, as covid-19 case counts began to tick up when the highly transmissible delta variant took hold in the state, …

The Delta Variant Thrives in a State of Political and Public Health Discord Read More »

EMA starts review of latecomer GSK/Sanofi COVID-19 vaccine

The EMA has kicked off a rolling review of a COVID-19 vaccine from Sanofi and GlaxoSmithKline, which started a 35,000-patient phase 3 trial in May. The vaccine – now dubbed Vidprevtyn – is based on a recombinant protein antigen developed by Sanofi’s vaccines unit Sanofi Pasteur, and also includes an immune-boosting adjuvant developed by GSK …

EMA starts review of latecomer GSK/Sanofi COVID-19 vaccine Read More »

Medical meetings post-COVID – key lessons for pharma

EPG Health’s Allen Wellings assesses future symposia and congress models, outlining some learnings about content and reach. COVID-19 had a huge, and very obvious, initial impact on medical congresses and symposia when 2020’s lockdowns took effect, with many events struggling to move quickly enough to a purely digital format. While many did succeed in creating …

Medical meetings post-COVID – key lessons for pharma Read More »

Regeneron’s Ronapreve Antibody Cocktail (casirivimab and imdevimab) Receives MHLW’s Approval for the Treatment of Mild to Moderate COVID-19

Shots: The approval is based on the results from a P-III trial evaluating Ronapreve (casirivimab and imdevimab) in high-risk non-hospitalized patients with COVID-19 The results showed a reduction in the risk of hospitalization or death by 70% in addition to the results from a P-I trial that demonstrated the safety, tolerability & PK in Japanese …

Regeneron’s Ronapreve Antibody Cocktail (casirivimab and imdevimab) Receives MHLW’s Approval for the Treatment of Mild to Moderate COVID-19 Read More »

Build back better: US pharma and the future of healthcare

America’s biopharmaceutical industry says it is “ready to do its part” in building a stronger, more resilient, affordable, and equitable health care system for all. COVID-19 highlighted both the challenges of the US healthcare system and the huge change potential of the country’s pharmaceutical industry. Now, as vaccination continues at pace, the sector has pledged …

Build back better: US pharma and the future of healthcare Read More »

Build back better: US pharma and the future of healthcare

America’s biopharmaceutical industry says it is “ready to do its part” in building a stronger, more resilient, affordable, and equitable health care system for all. COVID-19 highlighted both the challenges of the US healthcare system and the huge change potential of the country’s pharmaceutical industry. Now, as vaccination continues at pace, the sector has pledged …

Build back better: US pharma and the future of healthcare Read More »

UK funds ‘long COVID’ research drive as restrictions ease

The UK government has provided almost £20 million ($27 million) in funding for 15 research projects aiming to look into the causes of long COVID, improve diagnosis and find new treatments for the condition. Long COVID is the term used to described people who still suffer from fatigue and other symptoms like breathlessness and muscle …

UK funds ‘long COVID’ research drive as restrictions ease Read More »

UK funds ‘long COVID’ research drive as restrictions ease

The UK government has provided almost £20 million ($27 million) in funding for 15 research projects aiming to look into the causes of long COVID, improve diagnosis and find new treatments for the condition. Long COVID is the term used to described people who still suffer from fatigue and other symptoms like breathlessness and muscle …

UK funds ‘long COVID’ research drive as restrictions ease Read More »

Grab Your Mask and Notepad, We’re Headed Back to California’s State Capitol

SACRAMENTO, Calif. — The best part about returning to the pandemic-besieged state Capitol is that the elected officials are so unused to seeing us reporters after more than a year that some are occasionally extra chatty. The bad part is that the masks make it harder to eavesdrop on the rest of them. Much like …

Grab Your Mask and Notepad, We’re Headed Back to California’s State Capitol Read More »

Novavax’s Effort to Vaccinate the World, From Zero to Not Quite Warp Speed

On a sweltering June morning, Novavax CEO and covid vaccine maker Stanley Erck stood on a stage unmasked and did something that would have been unthinkable six months ago: He shook hands with Maryland’s governor. Erck was with Gov. Larry Hogan to announce Novavax’s global vaccine headquarters ― a campus expected to house laboratories and …

Novavax’s Effort to Vaccinate the World, From Zero to Not Quite Warp Speed Read More »

Fútbol, banderas y diversión: estrategias creativas para vacunar a los latinos en Colorado

Los tambores se escuchaban sin parar mientras los fanáticos de la selección mexicana de fútbol se reunían en Empower Field, en Mile High, para un partido de fútbol internacional. Pero dentro de una casa rodante médica móvil estacionada cerca del estadio, había silencio y el tono era profesional. Durante el medio tiempo del partido de …

Fútbol, banderas y diversión: estrategias creativas para vacunar a los latinos en Colorado Read More »

Fútbol, Flags and Fun: Getting Creative to Reach Unvaccinated Latinos in Colorado

Horns blared and drums pounded a constant beat as fans of the Mexican national soccer team gathered recently at Empower Field at Mile High in Denver for a high-profile international tournament. But the sounds were muted inside a mobile medical RV parked near the stadium, and the tone was professional. During halftime of Mexico’s game …

Fútbol, Flags and Fun: Getting Creative to Reach Unvaccinated Latinos in Colorado Read More »

KHN’s ‘What the Health?’: Here Comes Reconciliation

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The expansion of health benefits is a major piece of the tentative budget deal reached this week by Democrats in Congress. They plan to press ahead — …

KHN’s ‘What the Health?’: Here Comes Reconciliation Read More »

AZ, J&J tweaking COVID shots to reduce clotting risks; report

AstraZeneca and Johnson & Johnson are both exploring ways to modify their COVID-19 vaccines to minimise the risk of severe blood clotting reactions that are seen – albeit rarely – in some people receiving the jabs. At the same time, the UK’s National Institute for Health and Care excellence (NICE) is developing guidance to help …

AZ, J&J tweaking COVID shots to reduce clotting risks; report Read More »

Red State, Blue State, Twin Outbreak: Behind Wyoming and Colorado’s Anomalous Covid Spikes

WHEATLAND, Wyo. — Brandon Graves said covid-19 arrived in Wheatland the way new movies do in this High Plains farming town: months after hitting the big cities and without much fanfare. “It kind of trickled in and it never really exploded here,” said Graves, a lifelong resident and mayor of the town of about 3,500, …

Red State, Blue State, Twin Outbreak: Behind Wyoming and Colorado’s Anomalous Covid Spikes Read More »

Hologic Receives CE Mark to Use Saliva Samples with Aptima SARS-CoV-2 Test in EU

Shots: The company has received a CE Mark for the use of saliva samples with the Aptima SARS-CoV-2 assay in the EU. The test runs on the fully automated Panther system The Aptima SARS-CoV-2 assay also received a CE Mark for nasopharyngeal and nasal swabs along with additional specimen types The company has broadened the …

Hologic Receives CE Mark to Use Saliva Samples with Aptima SARS-CoV-2 Test in EU Read More »

KHN’s ‘What the Health?’: Becerra Urges Congress to Expand Medicare, Address Rx Prices

Can’t see the audio player? Click here to listen on SoundCloud. You can also listen on Spotify, Apple Podcasts, Stitcher, Pocket Casts or wherever you listen to podcasts. The Biden administration stands ready to work with Congress to address drug prices and expand Medicare, Health and Human Services Secretary Xavier Becerra said in a wide-ranging …

KHN’s ‘What the Health?’: Becerra Urges Congress to Expand Medicare, Address Rx Prices Read More »

Simulation tech played key role in staff training at this academic medical center during Covid-19

Amid the Covid-19 pandemic, the University of Nebraska Medical Center turned to patient simulation and visualization technologies to help train its staff on coronavirus-specific clinical protocols. Developed along with Gaumard Scientific, the provider’s medical simulation facility was able to train thousands of healthcare professionals over the course of the public health crisis.

A Hamiltonian View of Post-Pandemic America

By MIKE MAGEE “In countries where there is great private wealth much may be effected by the voluntary contributions of patriotic individuals, but in a community situated like that of the United States, the public purse must supply the deficiency of private resource. In what can it be so useful as in prompting and improving …

A Hamiltonian View of Post-Pandemic America Read More »

UK study raises hopes of long COVID test within months

A diagnostic test to detect long COVID could be available within six to 12 months, following the discovery that patients with the chronic condition have distinctive antibodies in their blood.  Researchers at Imperial College London (ICL) led by Professor Danny Altmann told the BBC’s Panorama programme that they have identified a pattern of antibodies in …

UK study raises hopes of long COVID test within months Read More »

Government Oversight of Covid Air Cleaners Leaves Gaping Holes

Stephen Matthew Shumaker counted on in-home, in-person demonstrations to drive his water filtration business, which serves the Atlanta area. So when covid-19 hit and no one was inviting people indoors, he turned to the air-cleaning part of his operation. He sent cards in the mail advertising air purifiers using ActivePure technology to new homeowners: “KILL …

Government Oversight of Covid Air Cleaners Leaves Gaping Holes Read More »

Journalists Tackle Delta Variant, Hospital Prices and Public Health Spending

Midwest correspondent Lauren Weber discussed the covid-19 delta variant on NPR’s “The 1A” on July 2. Click here to hear Weber on NPR Senior correspondent Julie Appleby discussed hospital price transparency on WGN’s “NewsNation Now” on July 2. Click here to watch Appleby on WGN Read Appleby’s “Hospital Prices Must Now Be Transparent. For Many …

Journalists Tackle Delta Variant, Hospital Prices and Public Health Spending Read More »

EMA finds possible link between mRNA COVID jabs and myocarditis

The EU medicines regulator has said that there is some evidence to suggest a possible link between mRNA-based vaccines for COVID-19 and rare cases of heart inflammation.  According to the EMA’s pharmacovigilance risk assessment committee (PRAC), labelling for Pfizer/BioNTech’s Comirnaty and Moderna’s Spikevax should be updated to reflect “very rare cases” of myocarditis and pericarditis …

EMA finds possible link between mRNA COVID jabs and myocarditis Read More »

Eyeing delta surge, Pfizer will file COVID-19 booster next month

With the COVID-19 delta variant has become the dominant strain circulating in the US, Pfizer and BioNTech have said they will ask the FDA and other regulators to approve a third dose of their Comirnaty vaccine to guard against a winter surge in cases.  The two companies have revealed data from an ongoing trial of …

Eyeing delta surge, Pfizer will file COVID-19 booster next month Read More »

An Update on Anti-Androgen Therapy for the Coronavirus

I blogged earlier this year about some interesting androgen antagonist results in coronavirus therapy. The idea is that the TMPRSS serine protease needs to be present at the cell membrane for the entire cell-entry pathway of the virus to work, and that androgen antagonists decrease its expression sharply. As the references in that earlier post …

An Update on Anti-Androgen Therapy for the Coronavirus Read More »

Gates Foundation backs COVID R&D at AI firm Exscientia

Artificial intelligence-based drug discovery company Exscientia is stepping up its search for new COVID-19 medicines, thanks to an award by the Bill & Melinda Gates Foundation.  The $1.5 million grant will be used to develop a new class of small-molecule inhibitors of Mpro , a protease enzyme essential for the replication of the SARS-CoV-2 virus. …

Gates Foundation backs COVID R&D at AI firm Exscientia Read More »

Delta Variant Surges in Colorado as the Bands Play On

GRAND JUNCTION, Colo. — Dr. Rachel LaCount grasped a metal hoop at a playground and spun in circles with her 7-year-old son, turning the distant mesas of the Colorado National Monument into a red-tinged blur. LaCount has lived in this western Colorado city of 64,000 nearly her whole life. As a hospital pathologist, she knows …

Delta Variant Surges in Colorado as the Bands Play On Read More »

Most Inmates Have Had Their Covid Shots — But Their Guards Likely Haven’t

When the number of covid-19 cases among inmates in Pennsylvania state prisons last fall topped 1,000 and staff cases hovered in the hundreds, the union representing 11,000 corrections officers began lobbying to get prison staffers to the front of the line for vaccinations. John Eckenrode, president of the Pennsylvania State Corrections Officers Association, pressed state …

Most Inmates Have Had Their Covid Shots — But Their Guards Likely Haven’t Read More »

Moderna plans triple vaccine targeting flu, COVID and RSV

Buoyed by the success of its COVID-19 vaccine, Moderna has started a phase 1/2 trials of its mRNA-based shot for seasonal influenza, targeting four different flu strains.  The first patents have now been enrolled into the study of the shot – codenamed mRNA-1010 – which is designed to generate antibodies against influenza A H1N1, H3N2 …

Moderna plans triple vaccine targeting flu, COVID and RSV Read More »

A life sciences vision to deliver health, wealth and resilience for the UK

The ABPI’s chief executive Dr Richard Torbett outlines a new ‘vision’ and 10-year strategy for UK life sciences, launched by the government today. After an extraordinary year of science versus disease, the UK has cemented itself at the forefront of the global response to COVID-19. What has been achieved in just 18 months is nothing …

A life sciences vision to deliver health, wealth and resilience for the UK Read More »