Can’t see the audio player? Click here to listen on SoundCloud. For the first time in a long time, there is some good news about the coronavirus pandemic: Although cases continue to climb, fewer people seem to be dying. And there are fewer cases than expected… Read More »KHN’s ‘What the Health?’: A Little Good News and Some Bad on COVID-19
SACRAMENTO, Calif. — In an election year dominated by a chaotic presidential race and splashy statewide ballot initiative campaigns, Californians are being asked to weigh in on the value of stem cell research — again. Proposition 14 would authorize the state to borrow $5.5 billion… Read More »Californians Asked to Pony Up for Stem Cell Research — Again
In mid-March, Karla Monterroso flew home to Alameda, California, after a hiking trip in Utah’s Zion National Park. Four days later, she began to develop a bad, dry cough. Her lungs felt sticky. The fevers that persisted for the next nine weeks grew so high… Read More »‘All You Want Is to Be Believed’: The Impacts of Unconscious Bias in Health Care
SACRAMENTO — A November ballot initiative to raise property taxes on big-business owners in California is drawing unconventional political support from health care power players and public health leaders. They see Proposition 15 as a potential savior for chronically underfunded local health departments struggling to… Read More »Health Care Groups Dive Into Property Tax Ballot Fight, Eyeing Public Health Money
California Healthline correspondent Angela Hart discussed how the coronavirus pandemic has derailed California’s efforts to deal with homelessness on KPBS “Midday Edition” on Oct. 8. Click here to hear Hart on KPBS Read “Hard Lives Made Harder by COVID: Homeless Endure a ‘Slow-Moving Train Wreck,’”… Read More »KHN on the Air This Week
Los Angeles County officials attribute a dramatic decline in COVID-19 death and case rates among Blacks and Latinos over the past two months to aggressive workplace health enforcement and the opening of tip lines to report violations. Now, officials intend to cement those gains by… Read More »COVID Crackdowns at Work Have Saved Black and Latino Lives, LA Officials Say
The Silicon Valley startup plans to start its registration-directed study of Limbix Spark in the earlier part of next year and – if successful – would anticipate FDA clearance in early 2022.
The convergence of the coronavirus pandemic and election season has complicated this year’s voting for residents of nursing homes, assisted living facilities and other long-term care centers. Many seniors who need help to get or fill out their ballots may be stymied by shifting rules… Read More »Pandemic Erects Barriers for Prized Bloc of Voters in Nursing Homes, Senior Facilities
The prize went to Jennifer Doudna of the University of California Berkeley and Emmanuelle Charpentier of the Max Planck Institute. Charpentier published her research on the biology behind the technology in 2011 and collaborated with Doudna. The two discovered it was possible to control the… Read More »CRISPR gene-editing discoverers awarded Nobel Prize in chemistry
CALEXICO, Calif. — The message wasn’t lost on Daniel Gonzalez. Early in the pandemic, one of the first things Imperial County did to ward off the virus was close the public bathrooms and, later, public cooling centers. In this sprawling Southern California desert, where summer… Read More »Hard Lives Made Harder by COVID: Homeless Endure a ‘Slow-Moving Train Wreck’
As trust in the Food and Drug Administration wavers, several states have vowed to conduct independent reviews of any COVID-19 vaccine the federal agency authorizes. But top health experts say such vetting may be misguided, even if it reflects a well-founded lack of confidence in… Read More »Distrusting Trump, States Plan to Vet COVID Vaccines Themselves. Bad Idea, Say Experts.
Cozbi Mazariegos stays in shape these days by running room to room inside her Marin City apartment to answer questions from her kids, ages 7, 10 and 12. They’re all working at home on laptops issued by their school, Bayside Martin Luther King Jr. Academy.… Read More »One School, Two Choices: A Study in Classroom vs. Distance Learning
The company did not provide data, but said results for patients who received sotorasib at the 960mg dose were consistent with those seen in the Phase I portion of the Phase I/II study, which showed an overall response rate of 35.3%. ……
Breaking up parties, confiscating booze and answering noise complaints — being a resident adviser has always required a willingness to be the “bad guy” and uphold university policy despite the protests of friends and peers. Now there’s a new element to the job description: COVID… Read More »Campus Dorm Resident Assistants Adjust to a New Role: COVID Cop
As the coronavirus pandemic broke out across the country, health care providers and scientists relied on the standard method for detecting respiratory viruses: sticking a long swab deep into the nose to get a sample. The obstacles to implementing such testing on a mass scale… Read More »Easier-to-Use Coronavirus Saliva Tests Start to Catch On
The company said it was meeting real-time supply demands for Veklury (remdesivir) in the U.S. and anticipated meeting global demands for the drug worldwide. AmerisourceBergen will continue acting as sole U.S. distributor.
Nils Hase, a retiree who lives in Tarpon Springs, Florida, is wearing a mask and loading his Home Depot haul into his car on a recent weekday afternoon. In the store, because Home Depot insists customers and staff across the country wear masks, most faces… Read More »Wear a Mask. If Only It Were That Simple.
As the smoke thickened near her home in Santa Cruz, California, last week, Amanda Smith kept asking herself the same questions: Should we leave? And where would we go? The wildfire evacuation zone, at the time, ended a few blocks from her house. But she… Read More »How to Weigh Evacuation Options With Both Wildfires and COVID at Your Door
It’s official, California: COVID-19 has left us sick with worry and increasingly despondent. And our youngest adults — ages 18 to 29 — are feeling it worst. Weekly surveys conducted by the U.S. Census Bureau from late April through late July offer a grim view… Read More »Feeling Anxious and Depressed? You’re Right at Home in California.
If you have declined to wear a face mask during the COVID-19 crisis, you might want to reconsider, as the smoke from over 300 wildfires chokes people across central and Northern California. But you are going to have to think a little more about what… Read More »Wildfires Provide Another Reason to Mask Up
Kronos Bio raises $155M in private financing to advance lead leukemia drug into registration study next year
The company has raised $148 million so far and plans to raise the remaining $7 million by next month. Its lead candidate is entospletinib, a SYK inhibitor acquired as part of a deal with Gilead Sciences last month, under development for patients with biomarker-defined acute… Read More »Kronos Bio raises $155M in private financing to advance lead leukemia drug into registration study next year
Yousuf El-Jayyousi, a junior engineering student at the University of Missouri, wanted guidance and reassurance that it would be safe to go back to school for the fall semester. He tuned into a pair of online town halls organized by the university hoping to find… Read More »Swab, Spit, Stay Home? College Coronavirus Testing Plans Are All Over the Map
The failure of California’s infectious disease monitoring system for a stretch of at least 20 days in July and August triggered potentially deadly fallout that continues to reverberate across the state. The fallout has been most severe in heavily populated counties, which rely primarily on… Read More »California’s Data Failures Stymie Efforts to Curb the Virus
While there had been some risks to filgotinib’s approval cited before, analysts expressed surprise at the decision, with one writing it would likely delay approval by at least a year. Shares of both companies fell sharply on the news.
In some ways, the nation’s COVID testing system is like a game of Jenga: When one piece falters, the entire tower collapses. Take Sacramento County, home to 1.5 million people and California’s capital. Coronavirus cases started surging in late June, and on July 15, 360… Read More »COVID Testing Choke Points
The update to the partnership includes opt-in rights for Gilead on 15 drug targets, up from five under the original 2018 deal. Gilead will pay $125 million upfront and make a $20 million equity investment in Tango, which focuses on synthetic lethality.
The French drugmaker will take full control of SAR442168, a BTK inhibitor developed for multiple sclerosis that it in-licensed from the California biotech company in 2017.
Shortages of personal protective equipment and medical supplies could persist for years without strategic government intervention, officials from health care and manufacturing industries have predicted. Officials said logistical challenges continue seven months after the coronavirus reached the United States, as the flu season approaches and… Read More »PPE Shortage Could Last Years Without Strategic Plan, Experts Warn
Earlier this month, Ohio Gov. Mike DeWine received a false-positive result from a rapid antigen test for Covid-19, raising concerns about the tests’ accuracy. The assay’s maker, Quidel, said it is investigating the case.
After terrorists slammed a plane into the Pentagon on 9/11, ambulances rushed scores of the injured to community hospitals, but only three of the patients were taken to specialized trauma wards. The reason: The hospitals and ambulances had no real-time information-sharing system. Nineteen years later,… Read More »COVID Data Failures Create Pressure for Public Health System Overhaul
UnitedHealthcare sent a notice to plan members stating that it would no longer cover Descovy to prevent HIV, while Truvada – after it goes generic next month – will be covered for free. Gilead reported that Descovy for PrEP had offset a second-quarter fall in… Read More »Gilead got a boost from a newly approved PrEP drug. Now, a major insurer is dropping coverage
As the coronavirus swept into Detroit this spring, Wayne State University junior Skye Taylor noticed something striking. On social media, many of her fellow Black classmates who live or grew up in the city were “posting about death, like, ‘Oh, I lost this family member… Read More »Turning Anger Into Action: Minority Students Analyze COVID Data on Racial Disparities
En una cálida tarde de finales de junio, la gente acudió en masa a las mesas al aire libre de la calle principal de esta ciudad para tomar sauvignon blanc, comer pizza cocinada en horno de leña y celebrar “Dining Under the Lights”, uno de… Read More »El coronavirus prolifera entre trabajadores latinos en un condado rico de California
SAN RAFAEL, Calif. — On a warm evening in late June, people flocked to alfresco tables set up along this town’s main drag to sip sauvignon blanc and eat wood-oven pizza for Dining Under the Lights, an event to welcome Marin County residents back to… Read More »In Health-Conscious Marin County, Virus Runs Rampant Among ‘Essential’ Latino Workers
Vilified, threatened with violence or in some cases suffering from burnout, dozens of state and local public health officials around the U.S. have resigned or have been fired amid the coronavirus outbreak, a testament to how politically combustible masks, lockdowns and infection data have become.… Read More »Public Health Officials Are Quitting or Getting Fired in Throes of Pandemic
California lawmakers are barreling toward an end-of-month deadline to pass or kill bills amid the biggest public health crisis the state has faced in a century. Yet even in a year consumed by sickness, they’re considering significant — sometimes controversial — health policy measures that… Read More »Amid COVID Chaos, California Legislators Fight for Major Health Care Bills
In a phone interview, Guardant Health CEO Helmy Eltoukhy said he expected the approval to encourage coverage by those payers still on the sidelines.
Gilead Sciences had said in its second-quarter earnings that it would partner with companies in North America, Europe and Asia to manufacture the antiviral drug, which received an emergency use authorization from the FDA in May.
Sabrina Lira Garcia is proud to work as a clinical assistant in the COVID-19 ward of a Los Angeles hospital, but sometimes she wishes she could just stay home with her infant son until the pandemic is over. Pulling her child from day care has… Read More »With Caveats, Hopeful News for Preschools Planning Young Kids’ Return
Premiums for health plans sold through Covered California, the state’s Affordable Care Act insurance exchange, will rise an average of 0.6% next year — the smallest hike since the exchange started providing coverage in 2014, the agency announced Tuesday. The modest increase follows an average… Read More »Covered California Announces Record-Low Rate Hike for 2021
Three of the companies making drugs used in the Phase II I-SPY COVID-19 study – Amgen, AbbVie and Takeda – announced the patient enrollments Monday. The study, which will enroll up to 1,500 critically ill patients, could test around 10 drugs.
SACRAMENTO — The tweet Richard Costigan posted July 23 was bluntly honest: “We tried our best to limit exposure to #COVID19 but we slipped up somewhere.” Costigan tweeted while waiting anxiously in the parking lot of a hospital outside Sacramento. The veteran Republican political consultant… Read More »California GOP Consultant Rues ‘Big Mistake’ That Led to Family’s COVID Infections
The company is hoping to close its seed funding round in the next six months and aims to be in a position to seek regulatory approval for its lead asset, PLX888, in acute alcoholic hepatitis in 2023.
These days, Los Angeles acting teacher Deryn Warren balances her pain with her fear. She’s a bladder cancer patient who broke her wrist in November. She still needs physical therapy for her wrist, and she’s months late for a cancer follow-up. But Warren won’t go… Read More »Avoiding Care During the Pandemic Could Mean Life or Death
When COVID-19 smacked the United States in March and April, health plans feared medical costs could skyrocket, jacking up premiums drastically in 2021, when millions of the newly unemployed might still be out of work. But something else happened: Non-COVID care collapsed as hospitals emptied… Read More »Don’t Count on Lower Premiums Despite Pandemic-Driven Boon for Insurers
When Will Lightbourne looked at the statistics behind California’s coronavirus cases, the disparities were “blindingly clear”: Blacks and Latinos are dying at higher rates than most other Californians. As of Monday, Latinos account for 45.6% of coronavirus deaths in a state where they make up… Read More »Medi-Cal Agency’s New Head Wants to Tackle Disparities and Racism
California’s outpatient health care practices largely shrugged off two recessions, adding more than 400,000 jobs during a two-decade climb from the start of 2000 to early 2020. It was an enviable growth rate of 85% and a trend largely mirrored on the national level. Then… Read More »Dental and Doctors’ Offices Still Struggling with COVID Job Loss
After spending a May day preparing her classroom to reopen for preschoolers, Ana Aguilar was informed that the tots would not have to wear face masks when they came back. What’s more, she had to sign a form agreeing not to sue the school if… Read More »Employers Require COVID Liability Waivers as Conflict Mounts Over Workplace Safety
Hiya! I’m Lauren Olsen, your new Newsletter Editor. That’s right — the totally official, no more fill-ins, always-here-for-you Newsletter Editor. As the replacement for editor extraordinaire Brianna Labuskes, I’m here to tackle all your health news needs. Why yes, you’re right — a pandemic is… Read More »Must-Reads of the Week From Lauren Olsen
The agency approved Tecartus, previously developed under the name KTE-X19, as the first CAR-T therapy for mantle cell lymphoma. The company had previously won approval for another CAR-T, Yescarta, in 2017, for diffuse large B-cell lymphoma.
MedCity spoke with Evidation and BrightInsight, two startups that have recently announced funding rounds, amid a Covid-19 pandemic worsening in the U.S.
HELENA, Montana — States frustrated by private laboratories’ increasingly long turnarounds for COVID-19 test results are scrambling to find ways to salvage their testing programs. Montana said Wednesday that it is dropping Quest Diagnostics, one of the nation’s largest diagnostic testing companies. The Secaucus, New… Read More »States Search for Ways to Deal With COVID-19 Testing Backlogs
The predictions were dire: Coronavirus lockdowns would put millions of Americans out of work, stripping them of their health insurance and pushing them into Medicaid, the health insurance program for low-income people. In California, Gov. Gavin Newsom’s administration projected that the pandemic would force about… Read More »Medicaid Mystery: Millions of Enrollees Haven’t Materialized in California
https://khn.org/wp-content/uploads/sites/2/2020/07/Anna-A-BTB-w-copyedit.mp4 Behind The Byline Watch More Videos Although the coronavirus pandemic shut down many organizations and businesses across the nation, KHN has never been busier — and health coverage has never been more vital. We’ve revamped our Behind The Byline YouTube series and brought it… Read More »Behind The Byline: ‘Reporting From a Distance’
While the disproportionate impact of COVID-19 on Black and Hispanic Americans is no secret, federal officials have launched studies of the disparity that they hope will better prepare the country for the next great epidemic. The National Institutes of Health began the ambitious “All of… Read More »NIH Project Homes In on COVID Racial Disparities
Use Our Content This story can be republished for free (details). Younger people are less likely to be hospitalized or die of COVID-19 than their elders, but they circulate more freely while carrying the disease, and their cases are harder to trace. Together, these facts… Read More »As Coronavirus Patients Skew Younger, Tracing Task Seems All But Impossible
The companies will use a combination of more than seven years of medical record data with five years of prospective data on 5,000 MS patients, including real-world outcomes data and MRI images. Other disease areas to be explored include hematology and rare diseases.
School leaders in Elk Grove, California, wanted to leave as little to chance as possible. So they brought nearly 150 voices into their decision-making process, and canvassed the parents of the estimated 63,000 students in the district to ask how they wanted their children taught.… Read More »California School Districts Grope for Sensible Reopening Plans
Use Nuestro Contenido Este contenido puede usarse de manera gratuita (detalles). Después de un encierro prolongado, anhelando un día en la playa o una noche en la ciudad —y atraídos por el alivio de las restricciones justo cuando llegan las cálidas temperaturas— muchas personas han… Read More »Puedes ver a amigos y familiares durante la pandemia, pero sigue estas reglas
Cooped up too long, yearning for a day at the beach or a night on the town — and enticed by the easing of restrictions just as the warm weather arrived — many people have bolted from the confines of home. And who can blame… Read More »You Can See Friends and Relatives During the Pandemic Surge — But Do It Carefully
The study is enrolling 60 healthy volunteers aged 18-45, but the company hopes it will form the basis of trials of the drug as an outpatient treatment for patients who do not require hospitalization. Remdesivir is currently administered via IV.
Research on the drug’s molecular target dates back to the 1950s. A spokesperson for Gilead noted that the company anticipates potentially investing more than $1 billion on the drug this year alone.
Three months ago, the nation watched as COVID-19 patients overwhelmed New York City’s intensive care units, forcing some of its hospitals to convert cafeterias into wards and pitch tents in parking lots. Hospitals elsewhere prepped for a similar surge: They cleared beds, stockpiled scarce protective… Read More »Amid Surge, Hospitals Hesitate To Cancel Nonemergency Surgeries
The company is currently running a Phase I study of its lead candidate, the antibody-drug conjugate VLS-101, in patients with lymphomas and leukemias. It has two additional antibody-drug conjugates and a bispecific antibody in preclinical development.
As I discuss in my video Which Intestines for Food and Cosmetics?, the Food and Drug Administration (FDA) recently reopened comments about its policy of allowing some intestines, but not others, into the U.S. food supply. When the first few cases of mad cow disease… Read More »Mad Cow Disease and Cosmetics