Antibiotics

Entasis antibiotic bests last-resort drug in Phase 3 trial; FDA filing planned for 2022

Entasis Therapeutics, the former anti-infectives unit of AstraZeneca, has positive Phase 3 data for its lead program, an antibiotic that could address drug-resistant strains of Acinetobacter baumannii that contribute to hospital-acquired infections. The biotech plans to seek FDA approval in 2022.

ViewPoints Article: Over Prescribed Medications and its Impact

Introduction: “Over-prescription” is defined as the action of prescribing a drug or treatment in greater amount or on more occasions than necessary. Overprescribing, in general in health care, has been a subject of frequent study. For instance, research published in 2018 found that 46% of a half-million outpatient antibiotic prescriptions were written by clinicians without diagnoses of …

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More research funding needed to avoid drug-resistant pandemic, warns report

Smaller firms are developing most antibiotics targeting superbugs but often at risk of bankruptcy Small drugmakers and biotech firms that are developing the bulk of new antibiotics need far more financial support, according to a new report, which warned that without these life-saving medicines there could be a pandemic of drug-resistant infections, worse than Covid-19. …

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Nutritional Yeast to Help Prevent Common Childhood Infections

The amount of beta-glucan fiber in just a dusting of nutritional yeast a day is put to the test in a randomized, double-blind, placebo-controlled trial for the prevention of common childhood illnesses. In 1989, the late Charles Janeway gave a presentation that was to revolutionize our understanding of the immune system. He proposed that we …

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Presumed Safety of Probiotics Questioned

In certain medical conditions, probiotic supplements may actually make things worse. If you’ve ever made sauerkraut at home, you know you don’t have to add any kind of starter bacteria to get it to ferment, because the lactic acid-producing bacteria are already present on the cabbage leaves themselves out in the field. This suggests that …

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Novo Holding launches latest call for antibiotic investment proposals

With the focus on COVID-19 over the last year it’s easy to forget another deadly pandemic caused by antimicrobial resistance (AMR), which could lead to the most innocuous of infections becoming life threatening. The Novo Holding REPAIR Impact Fund is hoping to change this with its latest call for investment proposals to fight AMR. While …

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How to Reduce Your TMAO Levels

Should we be concerned about high-choline plant foods such as broccoli producing the same toxic TMAO that results from eating high-choline animal foods such as eggs? Choline- and carnitine-rich foods—meat, eggs, and dairy—can be converted by our gut flora into trimethylamine, which in our livers is then turned into TMAO, a toxic compound that may …

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Where Does the Arsenic in Rice, Mushrooms, and Wine Come From?

What happens when our crops are grown in soil contaminated with arsenic-based pesticides and arsenic drug-laced chicken manure? When arsenic-containing drugs are fed to chickens, not only does the arsenic grow out into their feathers, which are then fed back to them as a slaughterhouse byproduct, but the arsenic can also get into their tissues …

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Why Was Chicken the Primary Source of Arsenic Exposure in Children?

What was the National Chicken Council’s response to public health authorities calling for the industry to stop feeding arsenic-based drugs to poultry? “Dietary practices influence our exposure to pesticides, toxic heavy metals, persistent organic pollutants, and industrial pollutants….A diet high in fish and other animal products, for example, results in greater exposure to persistent organic compounds …

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Kidney Toxins Created by Meat Consumption

As I discuss in my video How to Treat Heart Failure and Kidney Failure with Diet, one way a diet rich in animal-sourced foods like meat, eggs, and cheese may contribute to heart disease, stroke, and death is through the production of an atherosclerosis-inducing substance called TMAO. With the help of certain gut bacteria, the …

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Honey better treatment for coughs and colds than antibiotics, study claims

Research suggests honey also more effective than many over-the-counter medicines Honey may be better than conventional treatments for coughs, blocked noses and sore throats, researchers have said. The substance is cheap, readily available, and has virtually no side-effects. Doctors can recommend it as a suitable alternative to antibiotics, which are often prescribed for such infections, …

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$1 billion antibiotic venture fund launched

Antibiotic resistance is a problem. One study from Europe found that in 2015 there were 33,110 deaths attributable to antibiotic resistance; accounting for morbidity as well, antibiotic resistance lead to a a decrease of 874,541 disability-adjusted life years. CDC data show that antibiotic resistant bacteria and fungi caused 35,900 deaths in 2019, 12,800 deaths due …

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